| mTOR-and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity SC Cheng, J Quintin, RA Cramer, KM Shepardson, S Saeed, V Kumar, ... science 345 (6204), 1250684, 2014 | 1823 | 2014 |
| Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity S Saeed, J Quintin, HHD Kerstens, NA Rao, A Aghajanirefah, F Matarese, ... science 345 (6204), 1251086, 2014 | 1507 | 2014 |
| Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity RJW Arts, B Novakovic, R Ter Horst, A Carvalho, S Bekkering, ... Cell metabolism 24 (6), 807-819, 2016 | 689 | 2016 |
| Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ... Nature immunology 17 (4), 406-413, 2016 | 509 | 2016 |
| CLEC5A is critical for dengue-virus-induced lethal disease ST Chen, YL Lin, MT Huang, MF Wu, SC Cheng, HY Lei, CK Lee, ... Nature 453 (7195), 672-676, 2008 | 464 | 2008 |
| The macrophage mannose receptor induces IL-17 in response to Candida albicans FL van de Veerdonk, RJ Marijnissen, BJ Kullberg, HJPM Koenen, ... Cell host & microbe 5 (4), 329-340, 2009 | 412 | 2009 |
| The macrophage mannose receptor induces IL-17 in response to Candida albicans FL van de Veerdonk, RJ Marijnissen, BJ Kullberg, HJPM Koenen, ... Cell host & microbe 5 (4), 329-340, 2009 | 412 | 2009 |
| Human TLR10 is an anti-inflammatory pattern-recognition receptor M Oosting, SC Cheng, JM Bolscher, R Vestering-Stenger, TS Plantinga, ... Proceedings of the National Academy of Sciences 111 (42), E4478-E4484, 2014 | 333 | 2014 |
| Interplay between Candida albicans and the mammalian innate host defense SC Cheng, LAB Joosten, BJ Kullberg, MG Netea Infection and immunity 80 (4), 1304-1313, 2012 | 323 | 2012 |
| Innate immune memory: towards a better understanding of host defense mechanisms J Quintin, SC Cheng, JWM van Der Meer, MG Netea Current opinion in immunology 29, 1-7, 2014 | 281 | 2014 |
| The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans SC Cheng, FL van de Veerdonk, M Lenardon, M Stoffels, T Plantinga, ... Journal of leukocyte biology 90 (2), 357-366, 2011 | 214 | 2011 |
| Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans SP Smeekens, A Ng, V Kumar, MD Johnson, TS Plantinga, C Van Diemen, ... Nature communications 4 (1), 1342, 2013 | 195 | 2013 |
| Growth of Candida albicans cells on the physiologically relevant carbon source lactate affects their recognition and phagocytosis by immune cells IV Ene, SC Cheng, MG Netea, AJP Brown Infection and immunity 81 (1), 238-248, 2013 | 153 | 2013 |
| Anti‐Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity LYA Chai, F Van De Veerdonk, RJ Marijnissen, SC Cheng, AL Khoo, ... Immunology 130 (1), 46-54, 2010 | 148 | 2010 |
| Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast DW Lowman, RR Greene, DW Bearden, MD Kruppa, M Pottier, ... Journal of Biological Chemistry 289 (6), 3432-3443, 2014 | 139 | 2014 |
| Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells E Lachmandas, M Beigier‐Bompadre, SC Cheng, V Kumar, ... European journal of immunology 46 (11), 2574-2586, 2016 | 135 | 2016 |
| Ubiquitin ligase TRIM62 regulates CARD9-mediated anti-fungal immunity and intestinal inflammation Z Cao, KL Conway, RJ Heath, JS Rush, ES Leshchiner, ZG Ramirez-Ortiz, ... Immunity 43 (4), 715-726, 2015 | 119 | 2015 |
| Fungal chitin induces trained immunity in human monocytes during cross-talk of the host with Saccharomyces cerevisiae L Rizzetto, DC Ifrim, S Moretti, N Tocci, SC Cheng, J Quintin, G Renga, ... Journal of Biological Chemistry 291 (15), 7961-7972, 2016 | 111 | 2016 |
| Candida albicans dampens host defense by downregulating IL-17 production SC Cheng, F van de Veerdonk, S Smeekens, LAB Joosten, ... The Journal of Immunology 185 (4), 2450-2457, 2010 | 108 | 2010 |
| Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors H Laayouni, M Oosting, P Luisi, M Ioana, S Alonso, I Ricaño-Ponce, ... Proceedings of the National Academy of Sciences 111 (7), 2668-2673, 2014 | 107 | 2014 |
Leo JoostenRadboud UMC Nijmegen, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-NapocaVerified email at radboudumc.nl
