The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension. NC Newnham M, South K, Bleda M, Auger W, Barberà JA, Bogaard H, Bunclar K ... European Respiratory Journal 53 (3), 2019 | 867* | 2019 |
Bombesin-like immunoreactivity in the lung J Wharton, JM Polak, SR Bloom, MA Ghatei, E Solcia, MR Brown, ... Nature 273 (5665), 769-770, 1978 | 516 | 1978 |
Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells J Wharton, JW Strange, GMO Møller, EJ Growcott, X Ren, AP Franklyn, ... American journal of respiratory and critical care medicine 172 (1), 105-113, 2005 | 489 | 2005 |
ETA and ETB receptors modulate the proliferation of human pulmonary artery smooth muscle cells N Davie, SJ Haleen, PD Upton, JM Polak, MH Yacoub, NW Morrell, ... American journal of respiratory and critical care medicine 165 (3), 398-405, 2002 | 452 | 2002 |
Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease KJ Carss, G Arno, M Erwood, J Stephens, A Sanchis-Juan, S Hull, K Megy, ... The American Journal of Human Genetics 100 (1), 75-90, 2017 | 439 | 2017 |
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension S Gräf, M Haimel, M Bleda, C Hadinnapola, L Southgate, W Li, J Hodgson, ... Nature communications 9 (1), 1416, 2018 | 363 | 2018 |
The visualisation of cardiovascular innervation in the guinea pig using antiserum to protein gene product 9.5 (PGP 9.5) S Gulbenkian, J Wharton, JM Polak Journal of the autonomic nervous system 18 (3), 235-247, 1987 | 322 | 1987 |
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration YY Zhao, YD Zhao, MK Mirza, JH Huang, HHSK Potula, SM Vogel, ... The Journal of clinical investigation 119 (7), 2009 | 316 | 2009 |
Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension A Sebkhi, JW Strange, SC Phillips, J Wharton, MR Wilkins Circulation 107 (25), 3230-3235, 2003 | 312 | 2003 |
Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits I Tachmazidou, D Süveges, JL Min, GRS Ritchie, J Steinberg, K Walter, ... The American Journal of Human Genetics 100 (6), 865-884, 2017 | 302* | 2017 |
Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights CJ Rhodes, LS Howard, M Busbridge, D Ashby, E Kondili, JSR Gibbs, ... Journal of the American College of Cardiology 58 (3), 300-309, 2011 | 301 | 2011 |
Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension GP Diller, S van Eijl, DO Okonko, LS Howard, O Ali, T Thum, SJ Wort, ... Circulation 117 (23), 3020-3030, 2008 | 283 | 2008 |
Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid L Zhao, CN Chen, N Hajji, E Oliver, E Cotroneo, J Wharton, D Wang, M Li, ... Circulation 126 (4), 455-467, 2012 | 279 | 2012 |
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients ED Michelakis, V Gurtu, L Webster, G Barnes, G Watson, L Howard, ... Science translational medicine 9 (413), eaao4583, 2017 | 270 | 2017 |
Ultrastructural evidence for the coexistence of calcitonin gene-related peptide and substance P in secretory vesicles of peripheral nerves in the guinea pig S Gulbenkian, A Merighi, J Wharton, IM Varndell, JM Polak Journal of neurocytology 15, 535-542, 1986 | 269 | 1986 |
Machine learning of three-dimensional right ventricular motion enables outcome prediction in pulmonary hypertension: a cardiac MR imaging study TJW Dawes, A de Marvao, W Shi, T Fletcher, GMJ Watson, J Wharton, ... Radiology 283 (2), 381-390, 2017 | 245 | 2017 |
Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension CJ Rhodes, J Wharton, LS Howard, JSR Gibbs, MR Wilkins Heart 97 (13), 1054-1060, 2011 | 243 | 2011 |
Calcitonin gene-related peptide immunoreactivity in afferent neurons supplying the urinary tract: combined retrograde tracing and immunohistochemistry HC Su, J Wharton, JM Polak, PK Mulderry, MA Ghatei, SJ Gibson, ... Neuroscience 18 (3), 727-747, 1986 | 224 | 1986 |
Differential distribution of angiotensin AT2receptors in the normal and failing human heart J Wharton, K Morgan, RAD Rutherford, JD Catravas, A Chester, ... Journal of Pharmacology and Experimental Therapeutics 284 (1), 323-336, 1998 | 216 | 1998 |
Prolyl-4 hydroxylase 2 (PHD2) deficiency in endothelial cells and hematopoietic cells induces obliterative vascular remodeling and severe pulmonary arterial hypertension in … Z Dai, M Li, J Wharton, MM Zhu, YY Zhao Circulation 133 (24), 2447-2458, 2016 | 215 | 2016 |