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John Wharton
John Wharton
Verified email at imperial.ac.uk
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Cited by
Year
The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.
NC Newnham M, South K, Bleda M, Auger W, Barberà JA, Bogaard H, Bunclar K ...
European Respiratory Journal 53 (3), 2019
867*2019
Bombesin-like immunoreactivity in the lung
J Wharton, JM Polak, SR Bloom, MA Ghatei, E Solcia, MR Brown, ...
Nature 273 (5665), 769-770, 1978
5161978
Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells
J Wharton, JW Strange, GMO Møller, EJ Growcott, X Ren, AP Franklyn, ...
American journal of respiratory and critical care medicine 172 (1), 105-113, 2005
4892005
ETA and ETB receptors modulate the proliferation of human pulmonary artery smooth muscle cells
N Davie, SJ Haleen, PD Upton, JM Polak, MH Yacoub, NW Morrell, ...
American journal of respiratory and critical care medicine 165 (3), 398-405, 2002
4522002
Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease
KJ Carss, G Arno, M Erwood, J Stephens, A Sanchis-Juan, S Hull, K Megy, ...
The American Journal of Human Genetics 100 (1), 75-90, 2017
4392017
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
S Gräf, M Haimel, M Bleda, C Hadinnapola, L Southgate, W Li, J Hodgson, ...
Nature communications 9 (1), 1416, 2018
3632018
The visualisation of cardiovascular innervation in the guinea pig using antiserum to protein gene product 9.5 (PGP 9.5)
S Gulbenkian, J Wharton, JM Polak
Journal of the autonomic nervous system 18 (3), 235-247, 1987
3221987
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration
YY Zhao, YD Zhao, MK Mirza, JH Huang, HHSK Potula, SM Vogel, ...
The Journal of clinical investigation 119 (7), 2009
3162009
Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension
A Sebkhi, JW Strange, SC Phillips, J Wharton, MR Wilkins
Circulation 107 (25), 3230-3235, 2003
3122003
Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits
I Tachmazidou, D Süveges, JL Min, GRS Ritchie, J Steinberg, K Walter, ...
The American Journal of Human Genetics 100 (6), 865-884, 2017
302*2017
Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights
CJ Rhodes, LS Howard, M Busbridge, D Ashby, E Kondili, JSR Gibbs, ...
Journal of the American College of Cardiology 58 (3), 300-309, 2011
3012011
Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension
GP Diller, S van Eijl, DO Okonko, LS Howard, O Ali, T Thum, SJ Wort, ...
Circulation 117 (23), 3020-3030, 2008
2832008
Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid
L Zhao, CN Chen, N Hajji, E Oliver, E Cotroneo, J Wharton, D Wang, M Li, ...
Circulation 126 (4), 455-467, 2012
2792012
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients
ED Michelakis, V Gurtu, L Webster, G Barnes, G Watson, L Howard, ...
Science translational medicine 9 (413), eaao4583, 2017
2702017
Ultrastructural evidence for the coexistence of calcitonin gene-related peptide and substance P in secretory vesicles of peripheral nerves in the guinea pig
S Gulbenkian, A Merighi, J Wharton, IM Varndell, JM Polak
Journal of neurocytology 15, 535-542, 1986
2691986
Machine learning of three-dimensional right ventricular motion enables outcome prediction in pulmonary hypertension: a cardiac MR imaging study
TJW Dawes, A de Marvao, W Shi, T Fletcher, GMJ Watson, J Wharton, ...
Radiology 283 (2), 381-390, 2017
2452017
Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension
CJ Rhodes, J Wharton, LS Howard, JSR Gibbs, MR Wilkins
Heart 97 (13), 1054-1060, 2011
2432011
Calcitonin gene-related peptide immunoreactivity in afferent neurons supplying the urinary tract: combined retrograde tracing and immunohistochemistry
HC Su, J Wharton, JM Polak, PK Mulderry, MA Ghatei, SJ Gibson, ...
Neuroscience 18 (3), 727-747, 1986
2241986
Differential distribution of angiotensin AT2receptors in the normal and failing human heart
J Wharton, K Morgan, RAD Rutherford, JD Catravas, A Chester, ...
Journal of Pharmacology and Experimental Therapeutics 284 (1), 323-336, 1998
2161998
Prolyl-4 hydroxylase 2 (PHD2) deficiency in endothelial cells and hematopoietic cells induces obliterative vascular remodeling and severe pulmonary arterial hypertension in …
Z Dai, M Li, J Wharton, MM Zhu, YY Zhao
Circulation 133 (24), 2447-2458, 2016
2152016
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