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John Wharton
John Wharton
Verified email at imperial.ac.uk
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Year
The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.
NC Newnham M, South K, Bleda M, Auger W, Barberà JA, Bogaard H, Bunclar K ...
European Respiratory Journal 53 (3), 2019
1394*2019
Bombesin-like immunoreactivity in the lung
J Wharton, JM Polak, SR Bloom, MA Ghatei, E Solcia, MR Brown, ...
Nature 273 (5665), 769-770, 1978
5131978
Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells
J Wharton, JW Strange, GMO Møller, EJ Growcott, X Ren, AP Franklyn, ...
American journal of respiratory and critical care medicine 172 (1), 105-113, 2005
4762005
ETA and ETB receptors modulate the proliferation of human pulmonary artery smooth muscle cells
N Davie, SJ Haleen, PD Upton, JM Polak, MH Yacoub, NW Morrell, ...
American journal of respiratory and critical care medicine 165 (3), 398-405, 2002
4452002
Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease
KJ Carss, G Arno, M Erwood, J Stephens, A Sanchis-Juan, S Hull, K Megy, ...
The American Journal of Human Genetics 100 (1), 75-90, 2017
4052017
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
S Gräf, M Haimel, M Bleda, C Hadinnapola, L Southgate, W Li, J Hodgson, ...
Nature communications 9 (1), 1416, 2018
3382018
The visualisation of cardiovascular innervation in the guinea pig using antiserum to protein gene product 9.5 (PGP 9.5)
S Gulbenkian, J Wharton, JM Polak
Journal of the autonomic nervous system 18 (3), 235-247, 1987
3231987
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration
YY Zhao, YD Zhao, MK Mirza, JH Huang, HHSK Potula, SM Vogel, ...
The Journal of clinical investigation 119 (7), 2009
3092009
Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension
A Sebkhi, JW Strange, SC Phillips, J Wharton, MR Wilkins
Circulation 107 (25), 3230-3235, 2003
3082003
Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights
CJ Rhodes, LS Howard, M Busbridge, D Ashby, E Kondili, JSR Gibbs, ...
Journal of the American College of Cardiology 58 (3), 300-309, 2011
2822011
Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension
GP Diller, S van Eijl, DO Okonko, LS Howard, O Ali, T Thum, SJ Wort, ...
Circulation 117 (23), 3020-3030, 2008
2792008
Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits
I Tachmazidou, D Süveges, JL Min, GRS Ritchie, J Steinberg, K Walter, ...
The American Journal of Human Genetics 100 (6), 865-884, 2017
276*2017
Ultrastructural evidence for the coexistence of calcitonin gene-related peptide and substance P in secretory vesicles of peripheral nerves in the guinea pig
S Gulbenkian, A Merighi, J Wharton, IM Varndell, JM Polak
Journal of neurocytology 15, 535-542, 1986
2711986
Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid
L Zhao, CN Chen, N Hajji, E Oliver, E Cotroneo, J Wharton, D Wang, M Li, ...
Circulation 126 (4), 455-467, 2012
2672012
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients
ED Michelakis, V Gurtu, L Webster, G Barnes, G Watson, L Howard, ...
Science translational medicine 9 (413), eaao4583, 2017
2492017
Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension
CJ Rhodes, J Wharton, LS Howard, JSR Gibbs, MR Wilkins
Heart 97 (13), 1054-1060, 2011
2302011
Machine learning of three-dimensional right ventricular motion enables outcome prediction in pulmonary hypertension: a cardiac MR imaging study
TJW Dawes, A de Marvao, W Shi, T Fletcher, GMJ Watson, J Wharton, ...
Radiology 283 (2), 381-390, 2017
2272017
Calcitonin gene-related peptide immunoreactivity in afferent neurons supplying the urinary tract: combined retrograde tracing and immunohistochemistry
HC Su, J Wharton, JM Polak, PK Mulderry, MA Ghatei, SJ Gibson, ...
Neuroscience 18 (3), 727-747, 1986
2241986
Differential distribution of angiotensin AT2receptors in the normal and failing human heart
J Wharton, K Morgan, RAD Rutherford, JD Catravas, A Chester, ...
Journal of Pharmacology and Experimental Therapeutics 284 (1), 323-336, 1998
2141998
Capsaicin induces a depletion of calcitonin gene-related peptide (CGRP)-immunoreactive nerves in the cardiovascular system of the guinea pig and rat
J Wharton, S Gulbenkian, PK Mulderry, MA Ghatei, GP McGregor, ...
Journal of the autonomic nervous system 16 (4), 289-309, 1986
2141986
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