Mitochondria as multifaceted regulators of cell death FJ Bock, SWG Tait Nature reviews Molecular cell biology 21 (2), 85-100, 2020 | 1783 | 2020 |
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency E Giampazolias, B Zunino, S Dhayade, F Bock, C Cloix, K Cao, A Roca, ... Nature cell biology 19 (9), 1116-1129, 2017 | 235 | 2017 |
Caspase-2 activation in the absence of PIDDosome formation C Manzl, G Krumschnabel, F Bock, B Sohm, V Labi, F Baumgartner, ... Journal of Cell Biology 185 (2), 291-303, 2009 | 185 | 2009 |
The enigma of caspase-2: the laymen's view G Krumschnabel, B Sohm, F Bock, C Manzl, A Villunger Cell Death & Differentiation 16 (2), 195-207, 2009 | 150 | 2009 |
RNA regulation by poly (ADP-ribose) polymerases FJ Bock, TT Todorova, P Chang Molecular cell 58 (6), 959-969, 2015 | 112 | 2015 |
Caspase-2 at a glance LL Fava, FJ Bock, S Geley, A Villunger Journal of cell science 125 (24), 5911-5915, 2012 | 111 | 2012 |
PARP13 regulates cellular mRNA post-transcriptionally and functions as a pro-apoptotic factor by destabilizing TRAILR4 transcript T Todorova, FJ Bock, P Chang Nature communications 5 (1), 5362, 2014 | 107 | 2014 |
RETRACTED: DNA-PKcs-PIDDosome: A Nuclear Caspase-2-Activating Complex with Role in G2/M Checkpoint Maintenance M Shi, CJ Vivian, KJ Lee, C Ge, K Morotomi-Yano, C Manzl, F Bock, ... Cell 136 (3), 508-520, 2009 | 104 | 2009 |
New directions in poly (ADP‐ribose) polymerase biology FJ Bock, P Chang The FEBS journal 283 (22), 4017-4031, 2016 | 97 | 2016 |
BAX/BAK-induced apoptosis results in caspase-8-dependent IL-1β maturation in macrophages D Chauhan, E Bartok, MM Gaidt, FJ Bock, J Herrmann, JM Seeger, P Broz, ... Cell reports 25 (9), 2354-2368. e5, 2018 | 94 | 2018 |
Poly (ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer T Todorova, FJ Bock, P Chang Trends in molecular medicine 21 (6), 373-384, 2015 | 80 | 2015 |
PIDDosome-independent tumor suppression by Caspase-2 C Manzl, L Peintner, G Krumschnabel, F Bock, V Labi, M Drach, ... Cell Death & Differentiation 19 (10), 1722-1732, 2012 | 68 | 2012 |
Tight sequestration of BH3 proteins by BCL-xL at subcellular membranes contributes to apoptotic resistance J Pécot, L Maillet, J Le Pen, C Vuillier, S de Carné Trécesson, A Fétiveau, ... Cell reports 17 (12), 3347-3358, 2016 | 65 | 2016 |
Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome C Manzl, LL Fava, G Krumschnabel, L Peintner, MC Tanzer, C Soratroi, ... Cell death & disease 4 (12), e942-e942, 2013 | 40 | 2013 |
When cell death goes wrong: inflammatory outcomes of failed apoptosis and mitotic cell death FJ Bock, JS Riley Cell Death & Differentiation 30 (2), 293-303, 2023 | 37 | 2023 |
P53-induced protein with a death domain (PIDD): master of puppets? FJ Bock, L Peintner, M Tanzer, C Manzl, A Villunger Oncogene 31 (45), 4733-4739, 2012 | 36 | 2012 |
Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3‐only proteins Bim and Bmf V Labi, D Bertele, C Woess, D Tischner, FJ Bock, S Schwemmers, ... EMBO molecular medicine 5 (1), 122-136, 2013 | 34 | 2013 |
Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death FJ Bock, E Sedov, E Koren, AL Koessinger, C Cloix, D Zerbst, D Athineos, ... Nature communications 12 (1), 6572, 2021 | 33 | 2021 |
Loss of PIDD limits NF-κB activation and cytokine production but not cell survival or transformation after DNA damage FJ Bock, G Krumschnabel, C Manzl, L Peintner, MC Tanzer, ... Cell Death & Differentiation 20 (4), 546-557, 2013 | 32 | 2013 |
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics AL Koessinger, C Cloix, D Koessinger, DH Heiland, FJ Bock, K Strathdee, ... Cell Death & Differentiation 29 (10), 2089-2104, 2022 | 14 | 2022 |