Florian Bock
Florian Bock
Department of Radiotherapy, Maastricht University
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Cited by
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Mitochondria as multifaceted regulators of cell death
FJ Bock, SWG Tait
Nature reviews Molecular cell biology 21 (2), 85-100, 2020
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency
E Giampazolias, B Zunino, S Dhayade, F Bock, C Cloix, K Cao, A Roca, ...
Nature cell biology 19 (9), 1116-1129, 2017
Caspase-2 activation in the absence of PIDDosome formation
C Manzl, G Krumschnabel, F Bock, B Sohm, V Labi, F Baumgartner, ...
Journal of Cell Biology 185 (2), 291-303, 2009
The enigma of caspase-2: the laymen's view
G Krumschnabel, B Sohm, F Bock, C Manzl, A Villunger
Cell Death & Differentiation 16 (2), 195-207, 2009
RNA regulation by poly (ADP-ribose) polymerases
FJ Bock, TT Todorova, P Chang
Molecular cell 58 (6), 959-969, 2015
Caspase-2 at a glance
LL Fava, FJ Bock, S Geley, A Villunger
Journal of cell science 125 (24), 5911-5915, 2012
RETRACTED: DNA-PKcs-PIDDosome: A Nuclear Caspase-2-Activating Complex with Role in G2/M Checkpoint Maintenance
M Shi, CJ Vivian, KJ Lee, C Ge, K Morotomi-Yano, C Manzl, F Bock, ...
Cell 136 (3), 508-520, 2009
PARP13 regulates cellular mRNA post-transcriptionally and functions as a pro-apoptotic factor by destabilizing TRAILR4 transcript
T Todorova, FJ Bock, P Chang
Nature communications 5 (1), 5362, 2014
New directions in poly (ADP‐ribose) polymerase biology
FJ Bock, P Chang
The FEBS journal 283 (22), 4017-4031, 2016
BAX/BAK-induced apoptosis results in caspase-8-dependent IL-1β maturation in macrophages
D Chauhan, E Bartok, MM Gaidt, FJ Bock, J Herrmann, JM Seeger, P Broz, ...
Cell reports 25 (9), 2354-2368. e5, 2018
Poly (ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer
T Todorova, FJ Bock, P Chang
Trends in molecular medicine 21 (6), 373-384, 2015
PIDDosome-independent tumor suppression by Caspase-2
C Manzl, L Peintner, G Krumschnabel, F Bock, V Labi, M Drach, ...
Cell Death & Differentiation 19 (10), 1722-1732, 2012
Tight sequestration of BH3 proteins by BCL-xL at subcellular membranes contributes to apoptotic resistance
J Pécot, L Maillet, J Le Pen, C Vuillier, S de Carné Trécesson, A Fétiveau, ...
Cell reports 17 (12), 3347-3358, 2016
Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome
C Manzl, LL Fava, G Krumschnabel, L Peintner, MC Tanzer, C Soratroi, ...
Cell death & disease 4 (12), e942-e942, 2013
P53-induced protein with a death domain (PIDD): master of puppets?
FJ Bock, L Peintner, M Tanzer, C Manzl, A Villunger
Oncogene 31 (45), 4733-4739, 2012
Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3‐only proteins Bim and Bmf
V Labi, D Bertele, C Woess, D Tischner, FJ Bock, S Schwemmers, ...
EMBO molecular medicine 5 (1), 122-136, 2013
Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death
FJ Bock, E Sedov, E Koren, AL Koessinger, C Cloix, D Zerbst, D Athineos, ...
Nature communications 12 (1), 6572, 2021
Loss of PIDD limits NF-κB activation and cytokine production but not cell survival or transformation after DNA damage
FJ Bock, G Krumschnabel, C Manzl, L Peintner, MC Tanzer, ...
Cell Death & Differentiation 20 (4), 546-557, 2013
When cell death goes wrong: inflammatory outcomes of failed apoptosis and mitotic cell death
FJ Bock, JS Riley
Cell Death & Differentiation 30 (2), 293-303, 2023
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics
AL Koessinger, C Cloix, D Koessinger, DH Heiland, FJ Bock, K Strathdee, ...
Cell Death & Differentiation 29 (10), 2089-2104, 2022
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