Terence Herbert
Terence Herbert
Professor of Pharmaceutical Science, University of Lincoln
Verified email at
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Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: a specific vascular action of insulin
K Kuboki, ZY Jiang, N Takahara, SW Ha, M Igarashi, T Yamauchi, ...
Circulation 101 (6), 676-681, 2000
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites
TP Herbert, AR Tee, CG Proud
Journal of Biological Chemistry 277 (13), 11591-11596, 2002
Identification of a protein linked to the genomic and subgenomic mRNAs of feline calicivirus and its role in translation.
TP Herbert, I Brierley, TDK Brown
Journal of General Virology 78 (5), 1033-1040, 1997
cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to …
E Gomez, C Pritchard, TP Herbert
Journal of Biological Chemistry 277 (50), 48146-48151, 2002
Evidence for rapamycin toxicity in pancreatic β-cells and a review of the underlying molecular mechanisms
AD Barlow, ML Nicholson, TP Herbert
Diabetes 62 (8), 2674-2682, 2013
Rapid induction of apoptosis mediated by peptides that bind initiation factor eIF4E
TP Herbert, R Fåhraeus, A Prescott, DP Lane, CG Proud
Current Biology 10 (13), 793-796, 2000
Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation
B Wicksteed, TP Herbert, C Alarcon, MK Lingohr, LG Moss, CJ Rhodes
Journal of Biological Chemistry 276 (25), 22553-22558, 2001
Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells
TP Herbert, GR Kilhams, IH Batty, CG Proud
Journal of Biological Chemistry 275 (15), 11249-11256, 2000
Acidosis-sensing glutamine pump SNAT2 determines amino acid levels and mammalian target of rapamycin signalling to protein synthesis in L6 muscle cells
K Evans, Z Nasim, J Brown, H Butler, S Kauser, H Varoqui, JD Erickson, ...
Journal of the American Society of Nephrology 18 (5), 1426-1436, 2007
Detection of the ORF3 polypeptide of feline calicivirus in infected cells and evidence for its expression from a single, functionally bicistronic, subgenomic mRNA
TP Herbert, I Brierley, TDK Brown
Journal of General Virology 77 (1), 123-127, 1996
Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2)
AD Barlow, J Xie, CE Moore, SC Campbell, JAM Shaw, ML Nicholson, ...
Diabetologia 55 (5), 1355-1365, 2012
A decrease in cellular energy status stimulates PERK-dependent eIF2α phosphorylation and regulates protein synthesis in pancreatic β-cells
E Gomez, ML Powell, A Bevington, TP Herbert
Biochemical Journal 410 (3), 485-493, 2008
A reevaluation of the role of the unfolded protein response in islet dysfunction: maladaptation or a failure to adapt?
TP Herbert, DR Laybutt
Diabetes 65 (6), 1472-1480, 2016
The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β-cell mass: implications in the development of type-2 diabetes
J Xie, TP Herbert
Cellular and Molecular Life Sciences 69 (8), 1289-1304, 2012
Inhibition of SNAT2 by metabolic acidosis enhances proteolysis in skeletal muscle
K Evans, Z Nasim, J Brown, E Clapp, A Amin, B Yang, TP Herbert, ...
Journal of the American Society of Nephrology 19 (11), 2119-2129, 2008
Glucose-stimulated Protein Synthesis in Pancreatic β-Cells Parallels an Increase in the Availability of the Translational Ternary Complex (eIF2-GTP· Met-tRNAi) and the …
E Gomez, ML Powell, IC Greenman, TP Herbert
Journal of Biological Chemistry 279 (52), 53937-53946, 2004
cAMP inhibits mammalian target of rapamycin complex-1 and-2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity
J Xie, GA Ponuwei, CE Moore, GB Willars, AR Tee, TP Herbert
Cellular signalling 23 (12), 1927-1935, 2011
PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells
CE Moore, O Omikorede, E Gomez, GB Willars, TP Herbert
Molecular Endocrinology 25 (2), 315-326, 2011
Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic β-cells
CEJ Moore, J Xie, E Gomez, TP Herbert
Journal of molecular biology 389 (3), 480-494, 2009
Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells
C Chen, M Cano, JJ Wang, J Li, C Huang, Q Yu, TP Herbert, JT Handa, ...
Antioxidants & Redox Signaling 20 (14), 2091-2106, 2014
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