Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes U Ozcan, Q Cao, E Yilmaz, AH Lee, NN Iwakoshi, E Ozdelen, G Tuncman, ... Science 306 (5695), 457-461, 2004 | 4544 | 2004 |
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response AH Lee, NN Iwakoshi, LH Glimcher Molecular and cellular biology 23 (21), 7448-7459, 2003 | 2461 | 2003 |
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease A Kaser, AH Lee, A Franke, JN Glickman, S Zeissig, H Tilg, ... Cell 134 (5), 743-756, 2008 | 1573 | 2008 |
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation AL Shaffer, M Shapiro-Shelef, NN Iwakoshi, AH Lee, SB Qian, H Zhao, ... Immunity 21 (1), 81-93, 2004 | 1195 | 2004 |
Regulation of hepatic lipogenesis by the transcription factor XBP1 AH Lee, EF Scapa, DE Cohen, LH Glimcher Science 320 (5882), 1492-1496, 2008 | 1109 | 2008 |
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 NN Iwakoshi, AH Lee, P Vallabhajosyula, KL Otipoby, K Rajewsky, ... Nature immunology 4 (4), 321-329, 2003 | 1055 | 2003 |
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages F Martinon, X Chen, AH Lee, LH Glimcher Nature immunology 11 (5), 411-418, 2010 | 1019 | 2010 |
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1α C Hetz, P Bernasconi, J Fisher, AH Lee, MC Bassik, B Antonsson, ... Science 312 (5773), 572-576, 2006 | 810 | 2006 |
ER stress sensor XBP1 controls anti-tumor immunity by disrupting dendritic cell homeostasis JR Cubillos-Ruiz, PC Silberman, MR Rutkowski, S Chopra, ... Cell 161 (7), 1527-1538, 2015 | 758 | 2015 |
The endoplasmic reticulum stress response in immunity and autoimmunity DJ Todd, AH Lee, LH Glimcher Nature reviews immunology 8 (9), 663-674, 2008 | 726 | 2008 |
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells AH Lee, NN Iwakoshi, KC Anderson, LH Glimcher Proceedings of the National Academy of Sciences 100 (17), 9946-9951, 2003 | 724 | 2003 |
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth L Romero-Ramirez, H Cao, D Nelson, E Hammond, AH Lee, H Yoshida, ... Cancer research 64 (17), 5943-5947, 2004 | 683 | 2004 |
XBP‐1 is required for biogenesis of cellular secretory machinery of exocrine glands AH Lee, GC Chu, NN Iwakoshi, LH Glimcher The EMBO journal 24 (24), 4368-4380, 2005 | 503 | 2005 |
Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway ZV Wang, Y Deng, N Gao, Z Pedrozo, DL Li, CR Morales, A Criollo, X Luo, ... Cell 156 (6), 1179-1192, 2014 | 370 | 2014 |
The X‐box binding protein‐1 transcription factor is required for plasma cell differentiation and the unfolded protein response NN Iwakoshi, AH Lee, LH Glimcher Immunological reviews 194 (1), 29-38, 2003 | 339 | 2003 |
Dual and opposing roles of the unfolded protein response regulated by IRE1α and XBP1 in proinsulin processing and insulin secretion AH Lee, K Heidtman, GS Hotamisligil, LH Glimcher Proceedings of the National Academy of Sciences 108 (21), 8885-8890, 2011 | 315 | 2011 |
Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP X Xu, JS So, JG Park, AH Lee Seminars in liver disease 33 (04), 301-311, 2013 | 292 | 2013 |
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice JS So, KY Hur, M Tarrio, V Ruda, M Frank-Kamenetsky, K Fitzgerald, ... Cell metabolism 16 (4), 487-499, 2012 | 286 | 2012 |
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development DJ Todd, LJ McHeyzer-Williams, C Kowal, AH Lee, BT Volpe, B Diamond, ... Journal of Experimental Medicine 206 (10), 2151-2159, 2009 | 252 | 2009 |
The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism JH Lee, P Giannikopoulos, SA Duncan, J Wang, CT Johansen, JD Brown, ... Nature medicine 17 (7), 812-815, 2011 | 227 | 2011 |