Steven Watterson
Steven Watterson
Lecturer in Computational Biology, University of Ulster
Verified email at
TitleCited byYear
The Systems Biology Graphical Notation (vol 27, pg 735, 2009)
N Le Novere, M Hucka, H Mi, S Moodie, F Schreiber, A Sorokin, E Demir, ...
NATURE BIOTECHNOLOGY 27 (9), 864-864, 2009
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response
M Blanc, WY Hsieh, KA Robertson, KA Kropp, T Forster, G Shui, P Lacaze, ...
Immunity 38 (1), 106-118, 2013
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis
M Blanc, WY Hsieh, KA Robertson, S Watterson, G Shui, P Lacaze, ...
PLoS-Biology 9 (3), 455, 2011
Logic models of pathway biology
S Watterson, S Marshall, P Ghazal
Drug discovery today 13 (9-10), 447-456, 2008
The genetics and screening of familial hypercholesterolaemia
R Henderson, M O’Kane, V McGilligan, S Watterson
Journal of Biomedical Science 23 (1), 39, 2016
A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway
A Mazein, S Watterson, WY Hsieh, WJ Griffiths, P Ghazal
Biochemical Pharmacology 86 (1), 56-66, 2013
Digital clocks: simple Boolean models can quantitatively describe circadian systems
OE Akman, S Watterson, A Parton, N Binns, AJ Millar, P Ghazal
Journal of The Royal Society Interface 9 (74), 2365-2382, 2012
Construction of a large scale integrated map of macrophage pathogen recognition and effector systems
S Raza, N McDerment, P Lacaze, K Robertson, S Watterson, Y Chen, ...
BMC systems biology 4 (1), 63, 2010
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway
KA Robertson, WY Hsieh, T Forster, M Blanc, H Lu, PJ Crick, E Yutuc, ...
PLoS Biol 14 (3), e1002364, 2016
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction
S Watterson, ML Guerriero, M Blanc, A Mazein, L Loewe, KA Robertson, ...
Biochimie 95 (3), 613-621, 2013
Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis
H Lu, S Talbot, KA Robertson, S Watterson, T Forster, D Roy, P Ghazal
Steroids 99, 219-229, 2015
Computational modelling of atherosclerosis
A Parton, V McGilligan, M O’Kane, FR Baldrick, S Watterson
Briefings in Bioinformatics 17 (4), 562-575, 2016
Use of logic theory in understanding regulatory pathway signaling in response to infection
S Watterson, P Ghazal
Future Microbiology 5 (2), 163-176, 2010
Regulation and feedback of cholesterol metabolism
A Mazein, S Watterson, HC Gibbs, W Hsieh, MB Abdullah, M Blanc, ...
Nature Precedings, 2011
Inferring Boolean networks with perturbation from sparse gene expression data: a general model applied to the interferon regulatory network
L Yu, S Watterson, S Marshall, P Ghazal
Molecular BioSystems 4 (10), 1024-1030, 2008
Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway
HE Benson, S Watterson, JL Sharman, CP Mpamhanga, A Parton, ...
British journal of pharmacology 174 (23), 4362-4382, 2017
The in silico macrophage: toward a better understanding of inflammatory disease
P Ghazal, S Watterson, K Robertson, DC Kluth
Genome Med 3 (1), 4, 2011
Translation from the quantified implicit process flow abstraction in SBGN-PD diagrams to Bio-PEPA illustrated on the cholesterol pathway
L Loewe, M Guerriero, S Watterson, S Moodie, P Ghazal, J Hillston
Transactions on computational systems biology XIII, 13-38, 2011
Inference of transition probabilities between the attractors in boolean networks with perturbation
L Yu, S Watterson, S Marshall, P Ghazal
2009 IEEE International Workshop on Genomic Signal Processing and Statistics …, 2009
The chiral and flavour projection of Dirac-Kahler fermions in the geometric discretization
S Watterson
International Journal of Geometric Methods in Modern Physics 5 (3), 1-18, 2007
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