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Huixian Wu
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Structure of the human κ-opioid receptor in complex with JDTic
H Wu, D Wacker, M Mileni, V Katritch, GW Han, E Vardy, W Liu, ...
Nature 485 (7398), 327-332, 2012
10762012
Structure of an agonist-bound human A2A adenosine receptor
F Xu, H Wu, V Katritch, GW Han, KA Jacobson, ZG Gao, V Cherezov, ...
Science 332 (6027), 322-327, 2011
9342011
Structural basis for molecular recognition at serotonin receptors
C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ...
Science 340 (6132), 610-614, 2013
5972013
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic
AA Thompson, W Liu, E Chun, V Katritch, H Wu, E Vardy, XP Huang, ...
Nature 485 (7398), 395-399, 2012
5902012
Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
H Wu, C Wang, KJ Gregory, GW Han, HP Cho, Y Xia, CM Niswender, ...
Science 344 (6179), 58-64, 2014
5862014
Structure of the human smoothened receptor bound to an antitumour agent
C Wang, H Wu, V Katritch, GW Han, XP Huang, W Liu, FY Siu, BL Roth, ...
Nature 497 (7449), 338-343, 2013
5442013
Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine
L Qin, I Kufareva, LG Holden, C Wang, Y Zheng, C Zhao, G Fenalti, H Wu, ...
Science 347 (6226), 1117-1122, 2015
4122015
Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs
C Wang, H Wu, T Evron, E Vardy, GW Han, XP Huang, SJ Hufeisen, ...
Nature communications 5 (1), 4355, 2014
2772014
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles
AA Thompson, JJ Liu, E Chun, D Wacker, H Wu, V Cherezov, RC Stevens
Methods 55 (4), 310-317, 2011
1052011
Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20
DJ Wasilko, ZL Johnson, M Ammirati, Y Che, MC Griffor, S Han, H Wu
Nature communications 11 (1), 3031, 2020
802020
Chemotype-selective modes of action of κ-opioid receptor agonists
E Vardy, PD Mosier, KJ Frankowski, H Wu, V Katritch, RB Westkaemper, ...
Journal of Biological Chemistry 288 (48), 34470-34483, 2013
682013
Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo
TB Sundberg, Y Liang, H Wu, HG Choi, ND Kim, T Sim, L Johannessen, ...
ACS chemical biology 11 (8), 2105-2111, 2016
662016
Copper-free cycloaddition of azide and alkyne in crystalline state facilitated by arene–perfluoroarene interactions
BB Ni, C Wang, H Wu, J Pei, Y Ma
Chemical communications 46 (5), 782-784, 2010
582010
Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease
ES Leshchiner, JS Rush, MA Durney, Z Cao, V Dančík, B Chittick, H Wu, ...
Proceedings of the National Academy of Sciences 114 (43), 11392-11397, 2017
502017
Evaluation of Molecular Modeling of Agonist Binding in Light of the Crystallographic Structure of an Agonist-Bound A2A Adenosine Receptor
F Deflorian, TS Kumar, K Phan, ZG Gao, F Xu, H Wu, V Katritch, ...
Journal of medicinal chemistry 55 (1), 538-552, 2012
422012
Acid-responsive organogel mediated by arene–perfluoroarene and hydrogen bonding interactions
H Wu, BB Ni, C Wang, F Zhai, Y Ma
Soft Matter 8 (20), 5486-5492, 2012
262012
Preclinical characterization of the Omicron XBB. 1.5-adapted BNT162b2 COVID-19 vaccine
K Modjarrad, Y Che, W Chen, H Wu, CI Cadima, A Muik, MS Maddur, ...
bioRxiv, 2023.11. 17.567633, 2023
52023
Structural basis of the acyl-transfer mechanism of human GPAT1
ZL Johnson, M Ammirati, DJ Wasilko, JS Chang, S Noell, TL Foley, ...
Nature Structural & Molecular Biology 30 (1), 22-30, 2023
22023
N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as CCR6 inhibitors
BS Gerstenberger, AC Flick, DWS Kung, VM Lombardo, JJ Mousseau, ...
US Patent 11,708,360, 2023
12023
N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as CCR6 inhibitors
BS Gerstenberger, AC Flick, VM Lombardo, JJ Mousseau, PM Nuhant, ...
US Patent 10,975,065, 2021
12021
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