Manu O. Platt, Ph.D.
Manu O. Platt, Ph.D.
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Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1 …
GP Sorescu, H Song, SL Tressel, J Hwang, S Dikalov, DA Smith, NL Boyd, ...
Circulation research 95 (8), 773-779, 2004
Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response
GP Sorescu, M Sykes, D Weiss, MO Platt, A Saha, J Hwang, N Boyd, ...
Journal of Biological Chemistry 278 (33), 31128-31135, 2003
Sickle cell biomechanics
GA Barabino, MO Platt, DK Kaul
Annual review of biomedical engineering 12, 345-367, 2010
Identification of therapeutic covariant microRNA clusters in hypoxia-treated cardiac progenitor cell exosomes using systems biology
WD Gray, KM French, S Ghosh-Choudhary, JT Maxwell, ME Brown, ...
Circulation research 116 (2), 255-263, 2015
Magnesium as a biodegradable and bioabsorbable material for medical implants
HS Brar, MO Platt, M Sarntinoranont, PI Martin, MV Manuel
Jom 61 (9), 31-34, 2009
Simulated microgravity using the Random Positioning Machine inhibits differentiation and alters gene expression profiles of 2T3 preosteoblasts
SJ Pardo, MJ Patel, MC Sykes, MO Platt, NL Boyd, GP Sorescu, M Xu, ...
American Journal of Physiology-Cell Physiology 288 (6), C1211-C1221, 2005
Experimental, systems, and computational approaches to understanding the microRNA-mediated reparative potential of cardiac progenitor cell–derived exosomes from pediatric patients
U Agarwal, A George, S Bhutani, S Ghosh-Choudhary, JT Maxwell, ...
Circulation research 120 (4), 701-712, 2017
Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis
MO Platt, RF Ankeny, GP Shi, D Weiss, JD Vega, WR Taylor, H Jo
American Journal of Physiology-Heart and Circulatory Physiology 292 (3 …, 2007
Sustained epidermal growth factor receptor levels and activation by tethered ligand binding enhances osteogenic differentiation of multi‐potent marrow stromal cells
MO Platt, AJ Roman, A Wells, DA Lauffenburger, LG Griffith
Journal of cellular physiology 221 (2), 306-317, 2009
Laminar shear stress inhibits cathepsin L activity in endothelial cells
MO Platt, RF Ankeny, H Jo
Arteriosclerosis, thrombosis, and vascular biology 26 (8), 1784-1790, 2006
Crohn’s disease: a review of treatment options and current research
S Bandzar, S Gupta, MO Platt
Cellular immunology 286 (1-2), 45-52, 2013
Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues
CL Wilder, KY Park, PM Keegan, MO Platt
Archives of biochemistry and biophysics 516 (1), 52-57, 2011
VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF
SM Anderson, B Shergill, ZT Barry, E Manousiouthakis, TT Chen, ...
Integrative biology 3 (9), 887-896, 2011
Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD
AO Awojoodu, PM Keegan, AR Lane, Y Zhang, KR Lynch, MO Platt, ...
Blood, The Journal of the American Society of Hematology 124 (12), 1941-1950, 2014
Cyclic pressure and shear stress regulate matrix metalloproteinases and cathepsin activity in porcine aortic valves
MO Platt, Y Xing, H Jo, AP Yoganathan
Journal of Heart Valve Disease 15 (5), 622, 2006
Muscadine grape skin extract can antagonize Snail-cathepsin L-mediated invasion, migration and osteoclastogenesis in prostate and breast cancer cells
LJ Burton, BA Smith, BN Smith, Q Loyd, P Nagappan, D McKeithen, ...
Carcinogenesis 36 (9), 1019-1027, 2015
Detection of femtomole quantities of mature cathepsin K with zymography
WA Li, ZT Barry, JD Cohen, CL Wilder, RJ Deeds, PM Keegan, MO Platt
Analytical biochemistry 401 (1), 91-98, 2010
Multipathway kinase signatures of multipotent stromal cells are predictive for osteogenic differentiation: Tissue‐specific stem cells
MO Platt, CL Wilder, A Wells, LG Griffith, DA Lauffenburger
Stem Cells 27 (11), 2804-2814, 2009
Age‐dependent effect of pediatric cardiac progenitor cells after juvenile heart failure
U Agarwal, AW Smith, KM French, AV Boopathy, A George, D Trac, ...
Stem cells translational medicine 5 (7), 883-892, 2016
Multiplex zymography captures stage-specific activity profiles of cathepsins K, L, and S in human breast, lung, and cervical cancer
B Chen, MO Platt
Journal of translational medicine 9 (1), 1-13, 2011
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