Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7380 | 2014 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1367 | 2018 |
Modeling linkage disequilibrium increases accuracy of polygenic risk scores BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ... The american journal of human genetics 97 (4), 576-592, 2015 | 1306 | 2015 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1138 | 2022 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1035 | 2019 |
Assessing the impact of population stratification on genetic association studies ML Freedman, D Reich, KL Penney, GJ McDonald, AA Mignault, ... Nature genetics 36 (4), 388-393, 2004 | 970 | 2004 |
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects CR Marshall, DP Howrigan, D Merico, B Thiruvahindrapuram, W Wu, ... Nature genetics 49 (1), 27-35, 2017 | 913 | 2017 |
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3β/β-catenin signaling Y Mao, X Ge, CL Frank, JM Madison, AN Koehler, MK Doud, C Tassa, ... Cell 136 (6), 1017-1031, 2009 | 900 | 2009 |
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ... The American Journal of Human Genetics 95 (5), 535-552, 2014 | 644 | 2014 |
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ... Cell 173 (7), 1705-1715. e16, 2018 | 507 | 2018 |
Excessive extracellular volume reveals a neurodegenerative pattern in schizophrenia onset O Pasternak, CF Westin, S Bouix, LJ Seidman, JM Goldstein, TUW Woo, ... Journal of Neuroscience 32 (48), 17365-17372, 2012 | 312 | 2012 |
Population genetic study of the brain-derived neurotrophic factor (BDNF) gene TL Petryshen, PC Sabeti, KA Aldinger, B Fry, JB Fan, SF Schaffner, ... Molecular psychiatry 15 (8), 810-815, 2010 | 294 | 2010 |
Support for involvement of neuregulin 1 in schizophrenia pathophysiology TL Petryshen, FA Middleton, A Kirby, KA Aldinger, S Purcell, AR Tahl, ... Molecular psychiatry 10 (4), 366-374, 2005 | 239 | 2005 |
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept B Franke, JL Stein, S Ripke, V Anttila, DP Hibar, KJE Van Hulzen, ... Nature neuroscience 19 (3), 420-431, 2016 | 237 | 2016 |
Genomewide linkage analysis of bipolar disorder by use of a high-density single-nucleotide–polymorphism (SNP) genotyping assay: a comparison with microsatellite marker assays … FA Middleton, MT Pato, KL Gentile, CP Morley, X Zhao, AF Eisener, ... The American Journal of Human Genetics 74 (5), 886-897, 2004 | 211 | 2004 |
Complement genes contribute sex-biased vulnerability in diverse disorders N Kamitaki, A Sekar, RE Handsaker, H De Rivera, K Tooley, DL Morris, ... Nature 582 (7813), 577-581, 2020 | 178 | 2020 |
Genetic investigation of chromosome 5q GABAA receptor subunit genes in schizophrenia TL Petryshen, FA Middleton, AR Tahl, GN Rockwell, S Purcell, ... Molecular psychiatry 10 (12), 1074-1088, 2005 | 155 | 2005 |
A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests FA Schroeder, MC Lewis, DM Fass, FF Wagner, YL Zhang, KM Hennig, ... PloS one 8 (8), e71323, 2013 | 154 | 2013 |
Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood G Ni, G Moser, S Ripke, BM Neale, A Corvin, JTR Walters, KH Farh, ... The American Journal of Human Genetics 102 (6), 1185-1194, 2018 | 141 | 2018 |
Genome-wide association studies of schizophrenia: does bigger lead to better results? SE Bergen, TL Petryshen Current opinion in psychiatry 25 (2), 76-82, 2012 | 137 | 2012 |