A next generation connectivity map: L1000 platform and the first 1,000,000 profiles A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ... Cell 171 (6), 1437-1452. e17, 2017 | 2731 | 2017 |
The Drug Repurposing Hub: a next-generation drug library and information resource SM Corsello, JA Bittker, Z Liu, J Gould, P McCarren, JE Hirschman, ... Nature medicine 23 (4), 405-408, 2017 | 857 | 2017 |
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ... Nature Cancer, 1-14, 2020 | 578 | 2020 |
A melanocyte lineage program confers resistance to MAP kinase pathway inhibition CM Johannessen, LA Johnson, F Piccioni, A Townes, DT Frederick, ... Nature 504 (7478), 138, 2013 | 485 | 2013 |
Gene expression inference with deep learning Y Chen, Y Li, R Narayan, A Subramanian, X Xie Bioinformatics 32 (12), 1832-1839, 2016 | 465 | 2016 |
Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state S Santagata, ML Mendillo, Y Tang, A Subramanian, CC Perley, SP Roche, ... Science 341 (6143), 2013 | 306 | 2013 |
Assessment of network module identification across complex diseases S Choobdar, ME Ahsen, J Crawford, M Tomasoni, T Fang, D Lamparter, ... Nature methods 16 (9), 843-852, 2019 | 268 | 2019 |
High-throughput phenotyping of lung cancer somatic mutations AH Berger, AN Brooks, X Wu, Y Shrestha, C Chouinard, F Piccioni, ... Cancer Cell 30 (2), 214-228, 2016 | 221 | 2016 |
Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map I Smith, PG Greenside, T Natoli, DL Lahr, D Wadden, I Tirosh, R Narayan, ... PLoS biology 15 (11), e2003213, 2017 | 213 | 2017 |
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling MJ Wawer, K Li, SM Gustafsdottir, V Ljosa, NE Bodycombe, MA Marton, ... Proceedings of the National Academy of Sciences 111 (30), 10911-10916, 2014 | 196 | 2014 |
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells KA Hartwell, PG Miller, S Mukherjee, AR Kahn, AL Stewart, DJ Logan, ... Nature chemical biology 9 (12), 840-848, 2013 | 139 | 2013 |
Distinct time scales in cortical discrimination of natural sounds in songbirds R Narayan, G Graņa, K Sen Journal of Neurophysiology 96 (1), 252-258, 2006 | 139 | 2006 |
Cortical discrimination of complex natural stimuli: can single neurons match behavior? L Wang, R Narayan, G Graņa, M Shamir, K Sen Journal of Neuroscience 27 (3), 582-589, 2007 | 136 | 2007 |
Cortical interference effects in the cocktail party problem R Narayan, V Best, E Ozmeral, E McClaine, M Dent, ... Nature neuroscience 10 (12), 1601, 2007 | 113 | 2007 |
Invariance and sensitivity to intensity in neural discrimination of natural sounds CP Billimoria, BJ Kraus, R Narayan, RK Maddox, K Sen Journal of Neuroscience 28 (25), 6304-6308, 2008 | 78 | 2008 |
The GCTx format and cmap {Py, R, M, J} packages: resources for optimized storage and integrated traversal of annotated dense matrices OM Enache, DL Lahr, TE Natoli, L Litichevskiy, D Wadden, C Flynn, ... Bioinformatics 35 (8), 1427-1429, 2018 | 65 | 2018 |
GeNets: a unified web platform for network-based genomic analyses T Li, A Kim, J Rosenbluh, H Horn, L Greenfeld, D An, A Zimmer, ... Nature methods, 1, 2018 | 53 | 2018 |
Spatial unmasking of birdsong in zebra finches (Taeniopygia guttata) and budgerigars (Melopsittacus undulatus). ML Dent, EM McClaine, V Best, E Ozmeral, R Narayan, FJ Gallun, K Sen, ... Journal of Comparative Psychology 123 (4), 357, 2009 | 40 | 2009 |
Non-oncology drugs are a source of previously unappreciated anti-cancer activity SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ... bioRxiv, 730119, 2019 | 38 | 2019 |
Delayed inhibition in cortical receptive fields and the discrimination of complex stimuli R Narayan, A Ergun, K Sen Journal of neurophysiology 94 (4), 2970-2975, 2005 | 37 | 2005 |