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Debapratim Dutta
Debapratim Dutta
Senior Research Scientist, Vertex Pharmaceuticals
Verified email at vrtx.com
Title
Cited by
Cited by
Year
Metalloriboswitches: RNA-based inorganic ion sensors that regulate genes
JE Wedekind, D Dutta, IA Belashov, JL Jenkins
Journal of Biological Chemistry 292 (23), 9441-9450, 2017
422017
Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation
GM Schroeder, D Dutta, CE Cavender, JL Jenkins, EM Pritchett, CD Baker, ...
Nucleic Acids Research 48 (14), 8146-8164, 2020
262020
Nucleobase mutants of a bacterial preQ1-II riboswitch that uncouple metabolite sensing from gene regulation
D Dutta, JE Wedekind
Journal of Biological Chemistry 295 (9), 2555-2567, 2020
162020
Chemically Accurate Relative Folding Stability of RNA Hairpins from Molecular Simulations
LG Smith, Z Tan, A Spasic, D Dutta, LA Salas-Estrada, A Grossfield, ...
Journal of chemical theory and computation 14 (12), 6598-6612, 2018
152018
Coupling Green Fluorescent Protein Expression with Chemical Modification to Probe Functionally Relevant Riboswitch Conformations in Live Bacteria
D Dutta, IA Belashov, JE Wedekind
Biochemistry, 2018
132018
Tails of Three Knotty Switches: How PreQ1 Riboswitch Structures Control Protein Translation
IA Belashov, D Dutta, M Salim, JE Wedekind
eLS, 1-11, 2015
42015
Gene Regulation Gets In Tune: how riboswitch tertiary-structure networks adapt to meet the needs of their transcription units
D Dutta, JE Wedekind
Journal of molecular biology 427 (22), 3469, 2015
32015
Relating Riboswitch Structure to Gene Regulation in Live Cells
D Dutta
University of Rochester, 2019
2019
Exploring Low-Energy Pathways that Interconvert the Apo and Bound States of a Metabolite-Sensing Gene-Regulatory RNA Switch
JE Wedekind, D Dutta, CE Cavender, AM DiCola, GM Schroeder, ...
Acta Crystallographica Section A: Foundations and Advances 75, a18-a18, 2019
2019
Elucidating Signal Transduction Pathways in RNA Mediated Gene Regulation
D Dutta, IA Belashov, JE Wedekind
Acta Crystallographica Section A: Foundations and Advances 74, a204-a204, 2018
2018
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