Javed Khan
Javed Khan
Deputy Branch Chief Genetics Branch, Senior Investigator, Center for Cancer Research, NCI, NIH
Verified email at - Homepage
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Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks
J Khan, JS Wei, M Ringner, LH Saal, M Ladanyi, F Westermann, ...
Nature medicine 7 (6), 673-679, 2001
The genetic landscape of high-risk neuroblastoma
TJ Pugh, O Morozova, EF Attiyeh, S Asgharzadeh, JS Wei, D Auclair, ...
Nature genetics 45 (3), 279-284, 2013
Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
Y Yu, J Khan, C Khanna, L Helman, PS Meltzer, G Merlino
Nature medicine 10 (2), 175-181, 2004
Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors
JF Shern, L Chen, J Chmielecki, JS Wei, R Patidar, M Rosenberg, ...
Cancer discovery 4 (2), 216-231, 2014
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
AP Hsu, EP Sampaio, J Khan, KR Calvo, JE Lemieux, SY Patel, ...
Blood, The Journal of the American Society of Hematology 118 (10), 2653-2655, 2011
Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays
J Khan, R Simon, M Bittner, Y Chen, SB Leighton, T Pohida, PD Smith, ...
Cancer Research 58 (22), 5009-5013, 1998
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
TF Eleveld, DA Oldridge, V Bernard, J Koster, LC Daage, SJ Diskin, ...
Nature genetics 47 (8), 864-871, 2015
The pediatric preclinical testing program: description of models and early testing results
PJ Houghton, CL Morton, C Tucker, D Payne, E Favours, C Cole, ...
Pediatric blood & cancer 49 (7), 928-940, 2007
International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee
PF Ambros, IM Ambros, GM Brodeur, M Haber, J Khan, A Nakagawara, ...
British journal of cancer 100 (9), 1471-1482, 2009
The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation
AS Brohl, DA Solomon, W Chang, J Wang, Y Song, S Sindiri, R Patidar, ...
PLoS genetics 10 (7), e1004475, 2014
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity
E Jacoby, SM Nguyen, TJ Fountaine, K Welp, B Gryder, H Qin, Y Yang, ...
Nature communications 7 (1), 12320, 2016
cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene
J Khan, ML Bittner, LH Saal, U Teichmann, DO Azorsa, GC Gooden, ...
Proceedings of the National Academy of Sciences 96 (23), 13264-13269, 1999
A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency
Q Zhou, GS Lee, J Brady, S Datta, M Katan, A Sheikh, MS Martins, ...
The American Journal of Human Genetics 91 (4), 713-720, 2012
Metastasis-associated differences in gene expression in a murine model of osteosarcoma
C Khanna, J Khan, P Nguyen, J Prehn, J Caylor, C Yeung, J Trepel, ...
Cancer research 61 (9), 3750-3759, 2001
Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models
JGT Vi, AT Cheuk, PS Tsang, JY Chung, YK Song, K Desai, Y Yu, ...
The Journal of clinical investigation 119 (11), 3395-3407, 2009
The MYCN oncogene is a direct target of miR-34a
JS Wei, YK Song, S Durinck, QR Chen, ATC Cheuk, P Tsang, Q Zhang, ...
Oncogene 27 (39), 5204-5213, 2008
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism
DA Oldridge, AC Wood, N Weichert-Leahey, I Crimmins, R Sussman, ...
Nature 528 (7582), 418-421, 2015
DNA microarray technology: the anticipated impact on the study of human disease
J Khan, ML Bittner, Y Chen, PS Meltzer, JM Trent
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1423 (2), M17-M28, 1999
Expression profiling in cancer using cDNA microarrays
J Khan, LH Saal, ML Bittner, Y Chen, JM Trent, PS Meltzer
ELECTROPHORESIS: An International Journal 20 (2), 223-229, 1999
Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents
JA Khan, X Tao, L Tong
Nature structural & molecular biology 13 (7), 582-588, 2006
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