Direct knock-on of desolvated ions governs strict ion selectivity in K+ channels W Kopec, DA Köpfer, ON Vickery, AS Bondarenko, TLC Jansen, ... Nature chemistry 10 (8), 813-820, 2018 | 183 | 2018 |
Molecular dynamics simulations of the interactions of medicinal plant extracts and drugs with lipid bilayer membranes W Kopeć, J Telenius, H Khandelia The FEBS journal 280 (12), 2785-2805, 2013 | 142 | 2013 |
Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling W Kopec, BS Rothberg, BL de Groot Nature communications 10 (1), 5366, 2019 | 93 | 2019 |
A β-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL T Schubeis, T Le Marchand, C Daday, W Kopec, K Tekwani Movellan, ... Proceedings of the National Academy of Sciences 117 (35), 21014-21021, 2020 | 62 | 2020 |
The N terminus of sarcolipin plays an important role in uncoupling sarco-endoplasmic reticulum Ca2+-ATPase (SERCA) ATP hydrolysis from Ca2+ transport SK Sahoo, SA Shaikh, DH Sopariwala, NC Bal, DS Bruhn, W Kopec, ... Journal of Biological Chemistry 290 (22), 14057-14067, 2015 | 61 | 2015 |
The persistent question of potassium channel permeation mechanisms A Mironenko, U Zachariae, BL de Groot, W Kopec Journal of Molecular Biology 433 (17), 167002, 2021 | 56 | 2021 |
The conduction pathway of potassium channels is water free under physiological conditions C Öster, K Hendriks, W Kopec, V Chevelkov, C Shi, D Michl, S Lange, ... Science Advances 5 (7), eaaw6756, 2019 | 52 | 2019 |
Tuning of the Na, K-ATPase by the beta subunit F Hilbers, W Kopec, TJ Isaksen, TH Holm, K Lykke-Hartmann, P Nissen, ... Scientific Reports 6 (1), 20442, 2016 | 48 | 2016 |
The Molecular Mechanism of Na+, K+-ATPase Malfunction in Mutations Characteristic for Adrenal Hypertension W Kopec, B Loubet, H Poulsen, H Khandelia Biophysical Journal 106 (2), 582a-583a, 2014 | 40 | 2014 |
Accelerating all-atom MD simulations of lipids using a modified virtual-sites technique B Loubet, W Kopec, H Khandelia Journal of chemical theory and computation 10 (12), 5690-5695, 2014 | 39 | 2014 |
The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management L Tranebjærg, N Strenzke, S Lindholm, ND Rendtorff, H Poulsen, ... Human Genetics 137, 111-127, 2018 | 35 | 2018 |
Effect of polycation structure on interaction with lipid membranes N Wilkosz, D Jamróz, W Kopec, K Nakai, S Yusa, M Wytrwal-Sarna, ... The Journal of Physical Chemistry B 121 (30), 7318-7326, 2017 | 34 | 2017 |
Molecular mechanism of polycation-induced pore formation in biomembranes N Awasthi, W Kopec, N Wilkosz, D Jamróz, JS Hub, M Zatorska, R Petka, ... ACS Biomaterials Science & Engineering 5 (2), 780-794, 2018 | 30 | 2018 |
Polycation–anionic lipid membrane interactions W Kopec, A Zak, D Jamróz, R Nakahata, S Yusa, V Gapsys, M Kepczynski Langmuir 36 (42), 12435-12450, 2020 | 25 | 2020 |
Reinforcing the membrane-mediated mechanism of action of the anti-tuberculosis candidate drug thioridazine with molecular simulations W Kopec, H Khandelia Journal of computer-aided molecular design 28, 123-134, 2014 | 23 | 2014 |
Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels S Cordeiro, RK Finol-Urdaneta, D Köpfer, A Markushina, J Song, ... Proceedings of the National Academy of Sciences 116 (3), 1059-1064, 2019 | 18 | 2019 |
Membrane accessibility of glutathione A Garcia, ND Eljack, MA Sani, F Separovic, HH Rasmussen, W Kopec, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (10), 2430-2436, 2015 | 18 | 2015 |
In silico assessment of the conduction mechanism of the Ryanodine Receptor 1 reveals previously unknown exit pathways LP Heinz, W Kopec, BL de Groot, RHA Fink Scientific Reports 8 (1), 6886, 2018 | 16 | 2018 |
Conformations of double-headed, triple-tailed phospholipid oxidation lipid products in model membranes A Hermetter, W Kopec, H Khandelia Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (8), 1700-1706, 2013 | 14 | 2013 |
K+ binding and proton redistribution in the E2P state of the H+, K+-ATPase V Dubey, M Han, W Kopec, IA Solov’yov, K Abe, H Khandelia Scientific Reports 8 (1), 12732, 2018 | 12 | 2018 |