CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage J Sun, J Carlson-Stevermer, U Das, M Shen, M Delenclos, AM Snead, ... Nature communications 10 (1), 53, 2019 | 93 | 2019 |
Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice M Shen, F Wang, M Li, N Sah, ME Stockton, JJ Tidei, Y Gao, ... Nature neuroscience 22 (3), 386-400, 2019 | 75 | 2019 |
Hippocampal deficits in neurodevelopmental disorders Y Li, M Shen, ME Stockton, X Zhao Neurobiology of learning and memory 165, 106945, 2019 | 54 | 2019 |
Mesolimbic leptin signaling negatively regulates cocaine-conditioned reward M Shen, C Jiang, P Liu, F Wang, L Ma Translational psychiatry 6 (12), e972-e972, 2016 | 51 | 2016 |
Optogenetic activation of GABAergic neurons in the nucleus accumbens decreases the activity of the ventral pallidum and the expression of cocaine-context-associated memory L Wang, M Shen, Y Yu, Y Tao, P Zheng, F Wang, L Ma International Journal of Neuropsychopharmacology 17 (5), 753-763, 2014 | 35 | 2014 |
Loss of MeCP2 in immature neurons leads to impaired network integration Y Sun, Y Gao, JJ Tidei, M Shen, JT Hoang, DF Wagner, X Zhao Human molecular genetics 28 (2), 245-257, 2019 | 34 | 2019 |
RGS6 mediates effects of voluntary running on adult hippocampal neurogenesis Y Gao, M Shen, JC Gonzalez, Q Dong, S Kannan, JT Hoang, BE Eisinger, ... Cell reports 32 (5), 2020 | 30 | 2020 |
GRK5 ablation contributes to insulin resistance L Wang, M Shen, F Wang, L Ma Biochemical and biophysical research communications 429 (1-2), 99-104, 2012 | 28 | 2012 |
GRK5 regulates social behavior via suppression of mTORC1 signaling in medial prefrontal cortex B Niu, P Liu, M Shen, C Liu, L Wang, F Wang, L Ma Cerebral cortex 28 (2), 421-432, 2018 | 24 | 2018 |
Parvalbumin interneurons of central amygdala regulate the negative affective states and the expression of corticotrophin-releasing hormone during morphine withdrawal L Wang, M Shen, C Jiang, L Ma, F Wang International Journal of Neuropsychopharmacology 19 (11), pyw060, 2016 | 23 | 2016 |
FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors M Shen, Y Guo, Q Dong, Y Gao, ME Stockton, M Li, S Kannan, ... Molecular Psychiatry 26 (11), 6845–6867, 2021 | 22 | 2021 |
GRK5 deficiency decreases diet-induced obesity and adipogenesis F Wang, L Wang, M Shen, L Ma Biochemical and Biophysical Research Communications 421 (2), 312-317, 2012 | 15 | 2012 |
Regulation of adult neurogenesis by the fragile X family of RNA binding proteins NE Patzlaff, M Shen, X Zhao Brain Plasticity 3 (2), 205-223, 2018 | 13 | 2018 |
A CRISPR/Cas9 based strategy to manipulate the Alzheimer’s amyloid pathway J Sun, J Carlson-Stevermer, U Das, M Shen, M Delenclos, AM Snead, ... BioRxiv, 310193, 2018 | 9 | 2018 |
Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway Y Guo, M Shen, Q Dong, NM Méndez-Albelo, SX Huang, CL Sirois, J Le, ... Nature Communications 14 (1), 3801, 2023 | 5 | 2023 |
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development M Shen, CL Sirois, Y Guo, M Li, Q Dong, NM Méndez-Albelo, Y Gao, ... Neuron 111 (24), 3988-4005. e11, 2023 | 2 | 2023 |
Rgs6 mediates effects of voluntary running on adult hippocampal neurogenesis XZ Y. GAO, M. SHEN, J. GONZALEZ, Q. DONG, S. KANNAN, B. EISINGER, Q. CHANG ... Neuroscience 2021, P009.10, 2021 | | 2021 |
Fxr1 knockout alters electrophysiological properties of parvalbumin-positive interneurons in somatosensory cortex MBJ K. SCHEUER, M. SHEN, X. ZHAO Neuroscience 2021, P055.08, 2021 | | 2021 |
Mitochondrial deficits contribute to impaired dendritic maturation in FXS human and mouse neurons XZ M. SHEN Neuroscience 2019, 366.03 / A60, 2019 | | 2019 |
O5‐05‐01: A CRISPR/CAS9 BASED STRATEGY TO ATTENUATE THE β‐AMYLOID PATHWAY J Sun, J Carlson-Stevermer, U Das, M Shen, L Wang, J Loi, A Petersen, ... Alzheimer's & Dementia 14 (7S_Part_31), P1655-P1655, 2018 | | 2018 |