The selectivity of protein kinase inhibitors: a further update J Bain, L Plater, M Elliott, N Shpiro, C Hastie, H Mclauchlan, I Klevernic, ... Biochem. J 408, 297-315, 2007 | 3051 | 2007 |
Mitogen-activated protein kinases in innate immunity JSC Arthur, SC Ley Nature Reviews Immunology 13 (9), 679-692, 2013 | 1869 | 2013 |
MSK2 and MSK1 mediate the mitogen-and stress-induced phosphorylation of histone H3 and HMG-14 A Soloaga, S Thomson, GR Wiggin, N Rampersaud, MH Dyson, ... The EMBO journal 22 (11), 2788-2797, 2003 | 614 | 2003 |
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells MR Williams, JSC Arthur, A Balendran, J van der Kaay, V Poli, P Cohen, ... Current Biology 10 (8), 439-448, 2000 | 596 | 2000 |
MSK1 and MSK2 are required for the mitogen-and stress-induced phosphorylation of CREB and ATF1 in fibroblasts GR Wiggin, A Soloaga, JM Foster, V Murray-Tait, P Cohen, JSC Arthur Molecular and cellular biology 22 (8), 2871-2881, 2002 | 538 | 2002 |
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains CH Emmerich, A Ordureau, S Strickson, JSC Arthur, PGA Pedrioli, ... Proceedings of the National Academy of Sciences 110 (38), 15247-15252, 2013 | 495 | 2013 |
Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division JSC Arthur, JS Elce, C Hegadorn, K Williams, PA Greer Molecular and cellular biology 20 (12), 4474-4481, 2000 | 438 | 2000 |
The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice MB Greenblatt, JH Shim, W Zou, D Sitara, M Schweitzer, D Hu, S Lotinun, ... The Journal of clinical investigation 120 (7), 2457, 2010 | 436 | 2010 |
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling O Ananieva, J Darragh, C Johansen, JM Carr, J McIlrath, JM Park, ... Nature immunology 9 (9), 1028-1036, 2008 | 401 | 2008 |
Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis—CREB and NF-κB as key regulators JM Park, FR Greten, A Wong, RJ Westrick, JSC Arthur, K Otsu, ... Immunity 23 (3), 319-329, 2005 | 391 | 2005 |
The kinase p38α serves cell type–specific inflammatory functions in skin injury and coordinates pro-and anti-inflammatory gene expression C Kim, Y Sano, K Todorova, BA Carlson, L Arpa, A Celada, T Lawrence, ... Nature immunology 9 (9), 1019-1027, 2008 | 341 | 2008 |
Parsing molecular and behavioral effects of cocaine in mitogen-and stress-activated protein kinase-1-deficient mice K Brami-Cherrier, E Valjent, D Hervé, J Darragh, JC Corvol, C Pages, ... The Journal of neuroscience 25 (49), 11444-11454, 2005 | 337 | 2005 |
Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase … M Brook, CR Tchen, T Santalucia, J McIlrath, JSC Arthur, J Saklatvala, ... Molecular and cellular biology 26 (6), 2408-2418, 2006 | 331 | 2006 |
Generation and characterization of p38β (MAPK11) gene-targeted mice VA Beardmore, HJ Hinton, C Eftychi, M Apostolaki, M Armaka, J Darragh, ... Molecular and cellular biology 25 (23), 10454-10464, 2005 | 329 | 2005 |
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90RSK and cAMP-dependent protein kinase, but not its farnesylation at … GP Sapkota, A Kieloch, JM Lizcano, S Lain, JSC Arthur, MR Williams, ... Journal of Biological Chemistry 276 (22), 19469-19482, 2001 | 325 | 2001 |
Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts N Dourdin, AK Bhatt, P Dutt, PA Greer, JSC Arthur, JS Elce, ... Journal of Biological Chemistry 276 (51), 48382-48388, 2001 | 323 | 2001 |
The nuclear kinase mitogen-and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation WB Chwang, JS Arthur, A Schumacher, JD Sweatt The Journal of Neuroscience 27 (46), 12732-12742, 2007 | 301 | 2007 |
p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP G Sabio, JSC Arthur, Y Kuma, M Peggie, J Carr, V Murray-Tait, F Centeno, ... The EMBO journal 24 (6), 1134-1145, 2005 | 300 | 2005 |
Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling Z Zhou, AT Tang, WY Wong, S Bamezai, LM Goddard, R Shenkar, S Zhou, ... Nature 532 (7597), 122-126, 2016 | 290 | 2016 |
Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages K Clark, KF MacKenzie, K Petkevicius, Y Kristariyanto, J Zhang, HG Choi, ... Proceedings of the National Academy of Sciences 109 (42), 16986-16991, 2012 | 288 | 2012 |