| Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells G Gallina, L Dolcetti, P Serafini, C De Santo, I Marigo, MP Colombo, ... The Journal of clinical investigation 116 (10), 2777-2790, 2006 | 969 | 2006 |
| IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice V Bronte, P Serafini, C De Santo, I Marigo, V Tosello, A Mazzoni, ... The Journal of Immunology 170 (1), 270-278, 2003 | 642 | 2003 |
| Derangement of immune responses by myeloid suppressor cells P Serafini, C De Santo, I Marigo, S Cingarlini, L Dolcetti, G Gallina, ... Cancer Immunology, Immunotherapy 53, 64-72, 2004 | 436 | 2004 |
| Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans C De Santo, M Salio, SH Masri, LYH Lee, T Dong, AO Speak, S Porubsky, ... The Journal of clinical investigation 118 (12), 4036-4048, 2008 | 404 | 2008 |
| Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination C De Santo, P Serafini, I Marigo, L Dolcetti, M Bolla, P Del Soldato, ... Proceedings of the National Academy of Sciences 102 (11), 4185-4190, 2005 | 366 | 2005 |
| Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A C De Santo, R Arscott, S Booth, I Karydis, M Jones, R Asher, M Salio, ... Nature immunology 11 (11), 1039-1046, 2010 | 353 | 2010 |
| Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment F Mussai, C De Santo, I Abu-Dayyeh, S Booth, L Quek, ... Blood, The Journal of the American Society of Hematology 122 (5), 749-758, 2013 | 315 | 2013 |
| B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo P Barral, J Eckl-Dorna, NE Harwood, C De Santo, M Salio, P Illarionov, ... Proceedings of the National Academy of Sciences 105 (24), 8345-8350, 2008 | 242 | 2008 |
| Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target F Mussai, S Egan, J Higginbotham-Jones, T Perry, A Beggs, E Odintsova, ... Blood, The Journal of the American Society of Hematology 125 (15), 2386-2396, 2015 | 182 | 2015 |
| MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers L Fultang, S Panetti, M Ng, P Collins, S Graef, N Rizkalla, S Booth, ... EBioMedicine 47, 235-246, 2019 | 135 | 2019 |
| Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity L Fultang, S Booth, O Yogev, B Martins da Costa, V Tubb, S Panetti, ... Blood, The Journal of the American Society of Hematology 136 (10), 1155-1160, 2020 | 106 | 2020 |
| Neuroblastoma arginase activity creates an immunosuppressive microenvironment that impairs autologous and engineered immunity F Mussai, S Egan, S Hunter, H Webber, J Fisher, R Wheat, C McConville, ... Cancer research 75 (15), 3043-3053, 2015 | 105 | 2015 |
| Molecular basis and current strategies of therapeutic arginine depletion for cancer L Fultang, A Vardon, C De Santo, F Mussai International Journal of Cancer 139 (3), 501-509, 2016 | 101 | 2016 |
| In vivo Administration of Artificial Antigen-Presenting Cells Activates Low-Avidity T Cells for Treatment of Cancer S Ugel, A Zoso, C De Santo, Y Li, I Marigo, P Zanovello, E Scarselli, ... Cancer research 69 (24), 9376-9384, 2009 | 83 | 2009 |
| Targeting the arginine metabolic brake enhances immunotherapy for leukaemia F Mussai, R Wheat, E Sarrou, S Booth, V Stavrou, L Fultang, T Perry, ... International journal of cancer 145 (8), 2201-2208, 2019 | 70 | 2019 |
| Combination lenalidomide and azacitidine: a novel salvage therapy in patients who relapse after allogeneic stem-cell transplantation for acute myeloid leukemia C Craddock, D Slade, C De Santo, R Wheat, P Ferguson, A Hodgkinson, ... Journal of Clinical Oncology 37 (7), 580, 2019 | 63 | 2019 |
| The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated‐recombinant arginase I BCT‐100 C De Santo, S Booth, A Vardon, A Cousins, V Tubb, T Perry, B Noyvert, ... International journal of cancer 142 (7), 1490-1502, 2018 | 60 | 2018 |
| Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma C De Santo, P Cheng, A Beggs, S Egan, A Bessudo, F Mussai Journal of hematology & oncology 11, 1-5, 2018 | 56 | 2018 |
| Macrophage-derived IL1β and TNFα regulate arginine metabolism in neuroblastoma L Fultang, LD Gamble, L Gneo, AM Berry, SA Egan, F De Bie, O Yogev, ... Cancer research 79 (3), 611-624, 2019 | 51 | 2019 |
| Tumor-derived GM-CSF promotes granulocyte immunosuppression in mesothelioma patients S Khanna, S Graef, F Mussai, A Thomas, N Wali, BG Yenidunya, C Yuan, ... Clinical Cancer Research 24 (12), 2859-2872, 2018 | 51 | 2018 |
