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John G. Cumming, PhD
John G. Cumming, PhD
Experienced medicinal chemist, AstraZeneca Pharmaceuticals
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Chemical predictive modelling to improve compound quality
JG Cumming, AM Davis, S Muresan, M Haeberlein, H Chen
Nature reviews Drug discovery 12 (12), 948-962, 2013
2682013
The total synthesis of swinholide A. Part 2: A stereocontrolled synthesis of a c1–c15 segment
I Paterson, JD Smith, RA Ward
Tetrahedron 51 (34), 9413-9436, 1995
1751995
Heterocyclic compounds useful as pharmaceutical agents
D Waterson, ESE Stokes, GR Brown, JG Cumming, NJ Newcombe, ...
US Patent 6,313,127, 2001
1102001
The total synthesis of swinholide A. Part 4: Synthesis of swinholide A and isoswinholide A from the protected monomeric seco acid, pre-swinholide A
I Paterson, KS Yeung, RA Ward, JD Smith, JG Cuimming, S Lamboley
Tetrahedron 51 (34), 9467-9486, 1995
1061995
Total synthesis of swinholide A and hemiswinholide A
I Paterson, KS Yeung, RA Ward, JG Cumming, JD Smith
Journal of the American Chemical Society 116 (20), 9391-9392, 1994
951994
Subcutaneous calcium heparin versus intravenous sodium heparin in treatment of established acute deep vein thrombosis of the legs: a multicentre prospective randomised trial.
MG Walker, JW Shaw, GJ Thomson, JG Cumming, ML Thomas
Br Med J (Clin Res Ed) 294 (6581), 1189-1192, 1987
801987
Novel, potent and selective anilinoquinazoline and anilinopyrimidine inhibitors of p38 MAP kinase
JG Cumming, CL McKenzie, SG Bowden, D Campbell, DJ Masters, ...
Bioorganic & medicinal chemistry letters 14 (21), 5389-5394, 2004
752004
Pharmaceutically active piperidine derivatives, in particular as modulators of chemokine receptor activity
J Burrows, A Cooper, J Cumming, T McInally, H Tucker
US Patent App. 10/276,430, 2004
722004
Studies in marine macrolide synthesis: Boron and silicon-mediated coupling strategies for Swinholide A
I Paterson, JG Cumming, JD Smith, RA Ward
Tetrahedron letters 35 (3), 441-444, 1994
711994
Synthesis and antiviral evaluation of enantiomeric 2′, 3′-dideoxy-and 2′, 3′-didehydro-2′, 3′-dideoxy-4′-thionucleosides
RJ Young, S Shaw-Ponter, JB Thomson, JA Miller, JG Cumming, ...
Bioorganic & Medicinal Chemistry Letters 5 (22), 2599-2604, 1995
691995
The total synthesis of swinholide A. Part 3: A stereocontrolled synthesis of (−)-pre-swinholide A.
I Paterson, RA Ward, JD Smith, JG Cumming, KS Yeung
Tetrahedron 51 (34), 9437-9466, 1995
691995
Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3, 3-diphenylpropyl)-piperidinyl amides and ureas
JN Burrows, JG Cumming, SM Fillery, GA Hamlin, JA Hudson, RJ Jackson, ...
Bioorganic & medicinal chemistry letters 15 (1), 25-28, 2005
582005
Substituted anilino-quinazoline (or quinoline) compounds and use thereof
JG Cumming, A AB, Morgan, L Bockius LLP, RL Raymond, TN Truong
US Patent 6,593,333, 2003
572003
A stereocontrolled synthesis of a C19-C32/C17-C30 Segment for swinholide A and misakinolide A, Cytotoxic dimeric macrolides from theonella swinhoei.
I Paterson, JG Cumming
Tetrahedron letters 33 (20), 2847-2850, 1992
531992
Dynamically resolved peri-substituted 2-formyl naphthamides: a new class of atropisomeric chiral auxiliary
J Clayden, C McCarthy, JG Cumming
Tetrahedron Letters 41 (18), 3279-3283, 2000
522000
Total Synthesis of (-)-Preswinholide A
I Paterson, JD Smith, RA Ward, JG Cumming
Journal of the American Chemical Society 116 (6), 2615-2616, 1994
471994
Automated QSAR with a hierarchy of global and local models
DJ Wood, D Buttar, JG Cumming, AM Davis, U Norinder, SL Rodgers
Molecular informatics 30 (11‐12), 960-972, 2011
452011
Towards the synthesis of swinholide A and scytophycin C. A highly stereocontrolled synthesis of (−)-pre-swinholide A
I Paterson, JG Cumming, JD Smith, RA Ward, KS Yeung
Tetrahedron letters 35 (20), 3405-3408, 1994
431994
Stereocontrolled assembly of tetrasubstituted tetrahydrofurans: a concise synthesis of virgatusin
T Akindele, SP Marsden, JG Cumming
Organic Letters 7 (17), 3685-3688, 2005
422005
Modulators of the human CCR5 receptor. Part 2: SAR of substituted 1-(3, 3-diphenylpropyl)-piperidinyl phenylacetamides
JG Cumming, AE Cooper, K Grime, CJ Logan, S McLaughlin, J Oldfield, ...
Bioorganic & medicinal chemistry letters 15 (22), 5012-5015, 2005
322005
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