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Barbara van Loon
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Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine
B van Loon, E Markkanen, U Hübscher
DNA repair 9 (6), 604-616, 2010
3632010
Pharmacological Inhibition of poly (ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle
E Pirinen, C Canto, YS Jo, L Morato, H Zhang, KJ Menzies, EG Williams, ...
Cell metabolism 19 (6), 1034-1041, 2014
2772014
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase λ
B van Loon, U Hübscher
Proceedings of the National Academy of Sciences 106 (43), 18201-18206, 2009
1302009
HUWE1 variants cause dominant X-linked intellectual disability: a clinical study of 21 patients
S Moortgat, S Berland, I Aukrust, I Maystadt, L Baker, V Benoit, ...
European Journal of Human Genetics 26 (1), 64-74, 2018
932018
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination
E Markkanen, B van Loon, E Ferrari, JL Parsons, GL Dianov, U Hübscher
Proceedings of the National Academy of Sciences 109 (2), 437-442, 2012
862012
Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair
G Maga, E Crespan, U Wimmer, B van Loon, A Amoroso, C Mondello, ...
Proceedings of the National Academy of Sciences 105 (52), 20689-20694, 2008
802008
HUWE1 mutations in Juberg-Marsidi and Brooks syndromes: the results of an X-chromosome exome sequencing study
MJ Friez, SS Brooks, RE Stevenson, M Field, MJ Basehore, LC Adès, ...
BMJ open 6 (4), e009537, 2016
612016
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7, 8-dihydroguanine bypass
G Maga, E Crespan, E Markkanen, R Imhof, A Furrer, G Villani, ...
Proceedings of the National Academy of Sciences 110 (47), 18850-18855, 2013
562013
Regulation of oxidative DNA damage repair: the adenine: 8-oxo-guanine problem
E Markkanen, U Hübscher, B van Loon
Cell Cycle 11 (6), 1070-1075, 2012
472012
Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair
E Crespan, A Furrer, M Rösinger, F Bertoletti, E Mentegari, G Chiapparini, ...
Nature communications 7 (1), 10805, 2016
452016
Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB)
B Van Loon, LD Samson
DNA repair 12 (3), 177-187, 2013
432013
The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase δ
N Selak, CZ Bachrati, I Shevelev, T Dietschy, B Loon, A Jacob, ...
Nucleic acids research 36 (16), 5166-5179, 2008
432008
Base excision repair in physiology and pathology of the central nervous system
M Bosshard, E Markkanen, B Van Loon
International journal of molecular sciences 13 (12), 16172-16222, 2012
402012
Base excision repair in physiology and pathology of the central nervous system
M Bosshard, E Markkanen, B Van Loon
International journal of molecular sciences 13 (12), 16172-16222, 2012
402012
Genotype–phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies
V Simonelli, S Camerini, F Mazzei, B Van Loon, A Allione, M D'Errico, ...
Free Radical Biology and Medicine 63, 401-409, 2013
372013
Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint
E Zucca, F Bertoletti, U Wimmer, E Ferrari, G Mazzini, S Khoronenkova, ...
Nucleic acids research 41 (1), 229-241, 2013
362013
Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity
E Mentegari, E Crespan, L Bavagnoli, M Kissova, F Bertoletti, ...
Nucleic acids research 45 (5), 2600-2614, 2017
342017
Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions
A Martín-Pardillos, A Tsaalbi-Shtylik, S Chen, S Lazare, RP Os, ...
Blood, The Journal of the American Society of Hematology 130 (13), 1523-1534, 2017
332017
The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants
D Fu, LD Samson, U Hübscher, B van Loon
DNA repair 35, 13-18, 2015
332015
The block of DNA polymerase δ strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase β and flap endonuclease 1
G Maga, B van Loon, E Crespan, G Villani, U Hubscher
Journal of biological chemistry 284 (21), 14267-14275, 2009
332009
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