Kyle Upton
Kyle Upton
Senior Research Officer, Mater Research Institute - University of Queensland
Verified email at mater.uq.edu.au
TitleCited byYear
Somatic retrotransposition alters the genetic landscape of the human brain
JK Baillie, MW Barnett, KR Upton, DJ Gerhardt, TA Richmond, F De Sapio, ...
Nature 479 (7374), 534, 2011
5742011
Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma
R Shukla, KR Upton, M Muñoz-Lopez, DJ Gerhardt, ME Fisher, T Nguyen, ...
Cell 153 (1), 101-111, 2013
2662013
Extensive somatic L1 retrotransposition in colorectal tumors
S Solyom, AD Ewing, EP Rahrmann, T Doucet, HH Nelson, MB Burns, ...
Genome research 22 (12), 2328-2338, 2012
2132012
Ubiquitous L1 mosaicism in hippocampal neurons
KR Upton, DJ Gerhardt, JS Jesuadian, SR Richardson, ...
Cell 161 (2), 228-239, 2015
1862015
The efficient generation of induced pluripotent stem (iPS) cells from adult mouse adipose tissue-derived and neural stem cells
PA Tat, H Sumer, KL Jones, K Upton, PJ Verma
Cell transplantation 19 (5), 525-536, 2010
852010
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells
S Klawitter, NV Fuchs, KR Upton, M Munoz-Lopez, R Shukla, J Wang, ...
Nature communications 7, 10286, 2016
802016
Reprogramming of somatic cells after fusion with induced pluripotent stem cells and nuclear transfer embryonic stem cells
H Sumer, KL Jones, J Liu, C Heffernan, PA Tat, KR Upton, PJ Verma
Stem cells and development 19 (2), 239-246, 2010
252010
Late passage human fibroblasts induced to pluripotency are capable of directed neuronal differentiation
J Liu, H Sumer, J Leung, K Upton, M Dottori, A Pébay, PJ Verma
Cell transplantation 20 (2), 193-204, 2011
242011
Is somatic retrotransposition a parasitic or symbiotic phenomenon?
KR Upton, JK Baillie, GJ Faulkner
Mobile genetic elements 1 (4), 279-328, 2011
152011
Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme
PE Carreira, AD Ewing, G Li, SN Schauer, KR Upton, AC Fagg, S Morell, ...
Mobile DNA 7 (1), 21, 2016
132016
L1 retrotransposon heterogeneity in ovarian tumor cell evolution
THM Nguyen, PE Carreira, FJ Sanchez-Luque, SN Schauer, AC Fagg, ...
Cell reports 23 (13), 3730-3740, 2018
112018
Pleiotropic Impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus
C Pridans, A Raper, GM Davis, J Alves, KA Sauter, L Lefevre, T Regan, ...
The Journal of Immunology 201 (9), 2683-2699, 2018
102018
Blood from ‘junk’: the LTR chimeric transcript Pu. 2 promotes erythropoiesis
KR Upton, GJ Faulkner
Mobile DNA 5 (1), 15, 2014
32014
Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines
JC Jiang, KR Upton
Mobile DNA 10 (1), 16, 2019
12019
Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells
S Klawitter, NV Fuchs, KR Upton, M Muñoz-Lopez, R Shukla, J Wang, ...
Nature communications 9 (1), 5398, 2018
12018
Proceedings of the Frontiers of Retrovirology Conference 2016
I Zurnic, S Hütter, U Lehmann, N Stanke, J Reh, T Kern, F Lindel, ...
Retrovirology 13 (1), 68, 2016
12016
Correction: Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus
C Pridans, A Raper, GM Davis, J Alves, KA Sauter, L Lefevre, T Regan, ...
The Journal of Immunology Author Choice 202 (11), 3334, 2019
2019
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells (vol 7, 10286, 2018)
S Klawitter, NV Fuchs, KR Upton, M Munoz-Lopez, R Shukla, J Wang, ...
NATURE COMMUNICATIONS 9, 2018
2018
Reprogramming triggers mobilisation of endogenous retrotransposons in human induced pluripotent stem cells with genotoxic effects on host gene expression
S Jung-Klawitter, NV Fuchs, KR Upton, A Froemmrich, C Miskey, ...
HUMAN GENE THERAPY 28 (12), A2-A2, 2017
2017
Reprogramming initiates mobilization of endogenous mutagenic LINE-1, Alu and SVA retrotransposons in human induced pluripotent stem cells with consequences for host gene expression
G Schumann, S Jung-Klawitter, NV Fuchs, KR Upton, M Munoz-Lopez, ...
Retrovirology 13, 2016
2016
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