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adrian thrasher
adrian thrasher
UCL/GOSH
Verified email at ucl.ac.uk
Title
Cited by
Cited by
Year
Effect of gene therapy on visual function in Leber's congenital amaurosis
JWB Bainbridge, AJ Smith, SS Barker, S Robbie, R Henderson, ...
New England Journal of Medicine 358 (21), 2231-2239, 2008
22202008
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
S Hacein-Bey-Abina, F Le Deist, F Carlier, C Bouneaud, C Hue, ...
New england journal of medicine 346 (16), 1185-1193, 2002
13672002
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
MG Ott, M Schmidt, K Schwarzwaelder, S Stein, U Siler, U Koehl, H Glimm, ...
Nature medicine 12 (4), 401-409, 2006
12962006
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
SJ Howe, MR Mansour, K Schwarzwaelder, C Bartholomae, M Hubank, ...
The Journal of clinical investigation 118 (9), 2008
12582008
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
S Stein, MG Ott, S Schultze-Strasser, A Jauch, B Burwinkel, A Kinner, ...
Nature medicine 16 (2), 198-204, 2010
8142010
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
HB Gaspar, KL Parsley, S Howe, D King, KC Gilmour, J Sinclair, G Brouns, ...
The Lancet 364 (9452), 2181-2187, 2004
7732004
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells
W Qasim, H Zhan, S Samarasinghe, S Adams, P Amrolia, S Stafford, ...
Science translational medicine 9 (374), eaaj2013, 2017
7272017
High-level transduction and gene expression in hematopoietic repopulating cells using a human imunodeficiency virus type 1-based lentiviral vector containing an internal spleen†…
C Demaison, K Parsley, G Brouns, M Scherr, K Battmer, C Kinnon, M Grez, ...
Human gene therapy 13 (7), 803-813, 2002
5832002
The cytoplasm of living cells behaves as a poroelastic material
E Moeendarbary, L Valon, M Fritzsche, AR Harris, DA Moulding, ...
Nature materials 12 (3), 253-261, 2013
5542013
Effective gene therapy with nonintegrating lentiviral vectors
RJ YŠnez-Munoz, KS Balaggan, A MacNeil, SJ Howe, M Schmidt, ...
Nature medicine 12 (3), 348-353, 2006
5232006
A robust model for read count data in exome sequencing experiments and implications for copy number variant calling
V Plagnol, J Curtis, M Epstein, KY Mok, E Stebbings, S Grigoriadou, ...
Bioinformatics 28 (21), 2747-2754, 2012
5142012
The wiskott-aldrich syndrome
HD Ochs, AJ Thrasher
Journal of Allergy and Clinical Immunology 117 (4), 725-738, 2006
4732006
Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency
C Picard, H Von Bernuth, P Ghandil, M Chrabieh, O Levy, PD Arkwright, ...
Medicine 89 (6), 403, 2010
4202010
Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors
U Modlich, S Navarro, D Zychlinski, T Maetzig, S Knoess, MH Brugman, ...
Molecular Therapy 17 (11), 1919-1928, 2009
4112009
WASP: a key immunological multitasker
AJ Thrasher, SO Burns
Nature Reviews Immunology 10 (3), 182-192, 2010
4022010
A modified γ-retrovirus vector for X-linked severe combined immunodeficiency
S Hacein-Bey-Abina, SY Pai, HB Gaspar, M Armant, CC Berry, S Blanche, ...
New England Journal of Medicine 371 (15), 1407-1417, 2014
3832014
Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy
RR Ali, GM Sarra, C Stephens, M Alwis, JWB Bainbridge, PM Munro, ...
Nature genetics 25 (3), 306-310, 2000
3742000
Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation
S Burns, AJ Thrasher, MP Blundell, L Machesky, GE Jones
Blood, The Journal of the American Society of Hematology 98 (4), 1142-1149, 2001
3692001
Hematopoietic stem-cell gene therapy for cerebral adrenoleukodystrophy
F Eichler, C Duncan, PL Musolino, PJ Orchard, S De Oliveira, AJ Thrasher, ...
New England Journal of Medicine 377 (17), 1630-1638, 2017
3672017
Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome
SHB Abina, HB Gaspar, J Blondeau, L Caccavelli, S Charrier, K Buckland, ...
Jama 313 (15), 1550-1563, 2015
3572015
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