| Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 113 | 2020 |
| TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw CC Gomes, T Gayden, A Bajic, OF Harraz, J Pratt, H Nikbakht, E Bareke, ... Nature communications 9 (1), 4572, 2018 | 73 | 2018 |
| DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis B Rivera, J Nadaf, S Fahiminiya, M Apellaniz-Ruiz, A Saskin, AS Chong, ... The Journal of clinical investigation 130 (3), 1479-1490, 2020 | 37 | 2020 |
| Structural analysis of the tobramycin and gentamicin clinical resistome reveals limitations for next-generation aminoglycoside design AV Bassenden, D Rodionov, K Shi, AM Berghuis ACS chemical biology 11 (5), 1339-1346, 2016 | 35 | 2016 |
| Drug-target networks in aminoglycoside resistance: hierarchy of priority in structural drug design VR Bacot-Davis, AV Bassenden, AM Berghuis MedChemComm 7 (1), 103-113, 2016 | 34 | 2016 |
| Structural basis for plazomicin antibiotic action and resistance T Golkar, AV Bassenden, K Maiti, DP Arya, TM Schmeing, AM Berghuis Communications Biology 4 (1), 729, 2021 | 12 | 2021 |
| De novo TRPV4 Leu619Pro variant causes a new channelopathy characterised by giant cell lesions of the jaws and skull, skeletal abnormalities and polyneuropathy A Ragamin, CC Gomes, K Bindels-de Heus, R Sandoval, AV Bassenden, ... Journal of medical genetics 59 (3), 305-312, 2022 | 11 | 2022 |
| Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC (2′) enzymes AV Bassenden, L Dumalo, J Park, J Blanchet, K Maiti, DP Arya, ... Scientific Reports 11 (1), 11614, 2021 | 10 | 2021 |
| Bisphosphoglycerate mutase deficiency protects against cerebral malaria and severe malaria-induced anemia G Xu, R Van Bruggen, CO Gualtieri, N Moradin, A Fois, D Vallerand, ... Cell reports 32 (12), 2020 | 7 | 2020 |
| ZBTB7B (ThPOK) is required for pathogenesis of cerebral malaria and protection against pulmonary tuberculosis JM Kennedy, A Georges, AV Bassenden, SM Vidal, AM Berghuis, ... Infection and Immunity 88 (2), 10.1128/iai. 00845-19, 2020 | 6 | 2020 |
| Effect of solvent and protein dynamics in ligand recognition and inhibition of aminoglycoside adenyltransferase 2 ″‐Ia VR Bacot‐Davis, AV Bassenden, T Sprules, AM Berghuis Protein Science 26 (9), 1852-1863, 2017 | 2 | 2017 |
| Revisiting the Catalytic Cycle and Kinetic Mechanism of Aminoglycoside O-Nucleotidyltransferase(2″): A Structural and Kinetic Study AV Bassenden, J Park, D Rodionov, AM Berghuis ACS Chemical Biology 15 (3), 686-694, 2020 | 1 | 2020 |
| Association of novel mutation in TRPV4 with familial nonsyndromic craniosynostosis with complete penetrance and variable expressivity T Gayden, G Crevier-Sorbo, W Jawhar, C Saint-Martin, R Eveleigh, ... Journal of Neurosurgery: Pediatrics 31 (6), 584-592, 2023 | | 2023 |
| Towards structure-guided design of next-generation aminoglycoside antibiotics A Bassenden McGill University, 2021 | | 2021 |
| Structural characterization of aminoglycoside modifying enzyme ANT (2"")-Ia A Bassenden, D Rodionov, N Sabet-Kassouf, T Haji, K Shi, A Berghuis Acta Crystallographica Section A: Foundations and Advances 70, C702-C702, 2014 | | 2014 |
