Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair K Lee, M Conboy, HM Park, F Jiang, HJ Kim, MA Dewitt, VA Mackley, ... Nature biomedical engineering 1 (11), 889-901, 2017 | 748 | 2017 |
Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours B Lee, K Lee, S Panda, R Gonzales-Rojas, A Chong, V Bugay, HM Park, ... Nature biomedical engineering 2 (7), 497-507, 2018 | 354 | 2018 |
Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering K Lee, VA Mackley, A Rao, AT Chong, MA Dewitt, JE Corn, N Murthy elife 6, e25312, 2017 | 152 | 2017 |
Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo HM Park, H Liu, J Wu, A Chong, V Mackley, C Fellmann, A Rao, F Jiang, ... Nature communications 9 (1), 3313, 2018 | 92 | 2018 |
In vivo delivery of transcription factors with multifunctional oligonucleotides K Lee, M Rafi, X Wang, K Aran, X Feng, C Lo Sterzo, R Tang, ... Nature materials 14 (7), 701-706, 2015 | 71 | 2015 |
Shape effect in the design of nanowire-coated microparticles as transepithelial drug delivery devices V Uskokovic, K Lee, PP Lee, KE Fischer, TA Desai ACS nano 6 (9), 7832-7841, 2012 | 64 | 2012 |
Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells K Lee, P Yu, N Lingampalli, HJ Kim, R Tang, N Murthy International journal of nanomedicine, 1841-1854, 2015 | 62 | 2015 |
Recent developments in intracellular protein delivery Y Zhang, JJ Rĝise, K Lee, J Li, N Murthy Current opinion in biotechnology 52, 25-31, 2018 | 61 | 2018 |
An oral microjet vaccination system elicits antibody production in rabbits K Aran, M Chooljian, J Paredes, M Rafi, K Lee, AY Kim, J An, JF Yau, ... Science translational medicine 9 (380), eaaf6413, 2017 | 52 | 2017 |
Optical imaging of intracellular reactive oxygen species for the assessment of the cytotoxicity of nanoparticles K Lee, H Lee, KW Lee, TG Park Biomaterials 32 (10), 2556-2565, 2011 | 45 | 2011 |
All-in-one nanowire-decorated multifunctional membrane for rapid cell lysis and direct DNA isolation H So, K Lee, N Murthy, AP Pisano ACS Applied Materials & Interfaces 6 (23), 20693-20699, 2014 | 37 | 2014 |
Physical delivery of macromolecules using high-aspect ratio nanostructured materials K Lee, N Lingampalli, AP Pisano, N Murthy, H So ACS applied materials & interfaces 7 (42), 23387-23397, 2015 | 23 | 2015 |
Hierarchical silicon nanospikes membrane for rapid and high-throughput mechanical cell lysis H So, K Lee, YH Seo, N Murthy, AP Pisano ACS applied materials & interfaces 6 (10), 6993-6997, 2014 | 22 | 2014 |
Gene editing therapeutics based on mRNA delivery J Popovitz, R Sharma, R Hoshyar, BS Kim, N Murthy, K Lee Advanced Drug Delivery Reviews, 115026, 2023 | 16 | 2023 |
Active agent delivery devices and methods of using the same K Aran, J Paredes, N Murthy, D Liepmann, K Lee US Patent 10,729,895, 2020 | 7 | 2020 |
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair. Nat Biomed Eng. 2017; 1: 889–901 K Lee, M Conboy, HM Park, F Jiang, HJ Kim, MA Dewitt, VA Mackley, ... | 6 | |
Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours. Nat Biomed Eng 2018; 2 (7): 497-507 B Lee, K Lee, S Panda, R Gonzales-Rojas, A Chong, V Bugay | 6 | |
TAxI-peptide targeted Cas12a ribonuclease protein nanoformulations increase genome editing in hippocampal neurons DL Sellers, K Lee, N Murthy, SH Pun Journal of Controlled Release 354, 188-195, 2023 | 5 | 2023 |
Dejad de propagar el mito de los estilos de aprendizaje P Kirschner Computers & Education 106 (1), 166-171, 2017 | 3 | 2017 |
Compositions and methods for target nucleic acid modification N Murthy, K Lee, IM Conboy, MJ Conboy US Patent App. 15/754,488, 2018 | 2 | 2018 |