CCL20/CCR6-mediated migration of regulatory T cells to the Helicobacter pylori-infected human gastric mucosa KW Cook, DP Letley, RJM Ingram, E Staples, H Skjoldmose, JC Atherton, ... Gut 63 (10), 1550-1559, 2014 | 156 | 2014 |
Citrullinated vimentin presented on MHC-II in tumor cells is a target for CD4+ T-cell–mediated antitumor immunity VA Brentville, RL Metheringham, B Gunn, P Symonds, I Daniels, M Gijon, ... Cancer research 76 (3), 548-560, 2016 | 101 | 2016 |
A Role for the Vacuolating Cytotoxin, VacA, in Colonization and Helicobacter pylori–Induced Metaplasia in the Stomach JA Winter, DP Letley, KW Cook, JL Rhead, AAM Zaitoun, RJM Ingram, ... The Journal of infectious diseases 210 (6), 954-963, 2014 | 100 | 2014 |
Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis KW Cook, J Crooks, K Hussain, K O’Brien, M Braitch, H Kareem, ... Frontiers in microbiology 6, 123776, 2015 | 72 | 2015 |
Helicobacter pylori downregulates expression of human β‐defensin 1 in the gastric mucosa in a type IV secretion‐dependent fashion SR Patel, K Smith, DP Letley, KW Cook, AA Memon, RJM Ingram, ... Cellular microbiology 15 (12), 2080-2092, 2013 | 58 | 2013 |
Citrullinated α-enolase is an effective target for anti-cancer immunity K Cook, I Daniels, P Symonds, T Pitt, M Gijon, W Xue, R Metheringham, ... Oncoimmunology 7 (2), e1390642, 2018 | 48 | 2018 |
Combination vaccine based on citrullinated vimentin and enolase peptides induces potent CD4-mediated anti-tumor responses VA Brentville, RL Metheringham, I Daniels, S Atabani, P Symonds, ... Journal for ImmunoTherapy of Cancer 8 (1), 2020 | 43 | 2020 |
SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors W Xue, VA Brentville, P Symonds, KW Cook, H Yagita, RL Metheringham, ... Oncotarget 7 (50), 83088, 2016 | 23 | 2016 |
T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; targeting of citrullinated self-peptides presented by HLA-DP4 for … VA Brentville, P Symonds, KW Cook, I Daniels, T Pitt, M Gijon, P Vaghela, ... Oncoimmunology 8 (5), e1576490, 2019 | 20 | 2019 |
Current strategies to enhance anti-tumour immunity KW Cook, LG Durrant, VA Brentville Biomedicines 6 (2), 37, 2018 | 17 | 2018 |
Novel tumour antigens and the development of optimal vaccine design VA Brentville, S Atabani, K Cook, LG Durrant Therapeutic advances in vaccines and immunotherapy 6 (2), 31-47, 2018 | 14 | 2018 |
PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy RH Choudhury, P Symonds, SJ Paston, I Daniels, KW Cook, M Gijon, ... Journal for Immunotherapy of Cancer 10 (2), 2022 | 12 | 2022 |
Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy KW Cook, W Xue, P Symonds, I Daniels, M Gijon, D Boocock, C Coveney, ... Journal for immunotherapy of cancer 9 (7), 2021 | 12 | 2021 |
Citrullinated epitopes identified on tumour MHC class II by peptide elution stimulate both regulatory and Th1 responses and require careful selection for optimal anti-tumour … P Symonds, A Marcu, KW Cook, RL Metheringham, LG Durrant, ... Frontiers in Immunology 12, 764462, 2021 | 11 | 2021 |
Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity K Cook, W Xue, S Atabani, P Symonds, A Al Omari, I Daniels, S Shah, ... Frontiers in Immunology 13, 873947, 2022 | 5 | 2022 |
A novel bivalent DNA vaccine encoding both spike protein receptor-binding domain and nucleocapsid protein of SARS-CoV-2 to elicit T cell and neutralising antibody responses … VA Brentville, M Vankemmelbeke, RL Methingham, P Symonds, KW Cook, ... Cold Spring Harbor Laboratory, 2021 | 5 | 2021 |
Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis. Front Microbiol. 2015; 6: 52 KW Cook, J Crooks, K Hussain, K O'Brien, M Braitch, H Kareem, ... External Resources Pubmed/Medline (NLM) Crossref (DOI), 2015 | 4 | 2015 |
What do cancer-specific T cells ‘see’? S Shah, A Al-Omari, KW Cook, SJ Paston, LG Durrant, VA Brentville Discovery Immunology 2 (1), kyac011, 2023 | 3 | 2023 |
Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy VA Brentville, P Symonds, JX Chua, A Skinner, I Daniels, KW Cook, ... Frontiers in Immunology 13, 1066185, 2022 | 2 | 2022 |
Immune responses to citrullinated and homocitrullinated peptides in healthy donors are not restricted to the HLA SE shared allele and can be selected into the memory pool RH Choudhury, I Daniels, P Vaghela, S Atabani, T Kirk, P Symonds, ... Immunology 169 (4), 467-486, 2023 | 1 | 2023 |