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Adam P Sharples
Adam P Sharples
Professor of Epigenetics and Molecular Physiology
Verified email at nih.no - Homepage
Title
Cited by
Cited by
Year
Human skeletal muscle possesses an epigenetic memory of hypertrophy
RA Seaborne, J Strauss, M Cocks, S Shepherd, TD O’Brien, ...
Scientific reports 8 (1), 1898, 2018
3002018
Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake
AP Sharples, DC Hughes, CS Deane, A Saini, C Selman, CE Stewart
Aging cell 14 (4), 511-523, 2015
2302015
Does skeletal muscle have an ‘epi’‐memory? The role of epigenetics in nutritional programming, metabolic disease, aging and exercise
AP Sharples, CE Stewart, RA Seaborne
Aging cell 15 (4), 603-616, 2016
2162016
A systems-based investigation into vitamin D and skeletal muscle repair, regeneration, and hypertrophy
DJ Owens, AP Sharples, I Polydorou, N Alwan, T Donovan, J Tang, ...
American Journal of Physiology-Endocrinology and Metabolism, 2015
1912015
Fuel for the work required: a practical approach to amalgamating train‐low paradigms for endurance athletes
SG Impey, KM Hammond, SO Shepherd, AP Sharples, C Stewart, M Limb, ...
Physiological reports 4 (10), e12803, 2016
1372016
Comparative transcriptome and methylome analysis in human skeletal muscle anabolism, hypertrophy and epigenetic memory
DC Turner, RA Seaborne, AP Sharples
Scientific reports 9 (1), 4251, 2019
1192019
Factors affecting the structure and maturation of human tissue engineered skeletal muscle
NRW Martin, SL Passey, DJ Player, A Khodabukus, RA Ferguson, ...
Biomaterials 34 (23), 5759-5765, 2013
982013
DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity
DC Turner, PP Gorski, MF Maasar, RA Seaborne, P Baumert, AD Brown, ...
Scientific Reports 10 (1), 15360, 2020
892020
Modelling in vivo skeletal muscle ageing in vitro using three‐dimensional bioengineered constructs
AP Sharples, DJ Player, NRW Martin, V Mudera, CE Stewart, MP Lewis
Aging cell 11 (6), 986-995, 2012
872012
An epigenetic clock for human skeletal muscle
S Voisin, NR Harvey, LM Haupt, LR Griffiths, KJ Ashton, VG Coffey, ...
Journal of cachexia, sarcopenia and muscle 11 (4), 887-898, 2020
862020
Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training
B Egan, AP Sharples
Physiological Reviews, 2023
832023
Methylome of human skeletal muscle after acute & chronic resistance exercise training, detraining & retraining
RA Seaborne, J Strauss, M Cocks, S Shepherd, TD O’brien, ...
Scientific data 5 (1), 1-9, 2018
812018
C2 and C2C12 murine skeletal myoblast models of atrophic and hypertrophic potential: Relevance to disease and ageing?
AP Sharples, N Al‐Shanti, CE Stewart
Journal of cellular physiology 225 (1), 240-250, 2010
812010
Skeletal muscle cells possess a ‘memory’of acute early life TNF-α exposure: role of epigenetic adaptation
AP Sharples, I Polydorou, DC Hughes, DJ Owens, TM Hughes, ...
Biogerontology 17, 603-617, 2016
782016
The interplay between exercise metabolism, epigenetics, and skeletal muscle remodeling
RA Seaborne, AP Sharples
Exercise and sport sciences reviews 48 (4), 188-200, 2020
732020
UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy
RA Seaborne, DC Hughes, DC Turner, DJ Owens, LM Baehr, P Gorski, ...
The Journal of physiology 597 (14), 3727-3749, 2019
692019
Reduction of myoblast differentiation following multiple population doublings in mouse C2C12 cells: A model to investigate ageing?
AP Sharples, N Al‐Shanti, MP Lewis, CE Stewart
Journal of cellular biochemistry 112 (12), 3773-3785, 2011
682011
Post‐exercise carbohydrate and energy availability induce independent effects on skeletal muscle cell signalling and bone turnover: implications for training adaptation
KM Hammond, C Sale, W Fraser, J Tang, SO Shepherd, JA Strauss, ...
The Journal of physiology 597 (18), 4779-4796, 2019
652019
Transcriptomic and epigenetic regulation of disuse atrophy and the return to activity in skeletal muscle
A Fisher, RA Seaborne, TM Hughes, A Gutteridge, CE Stewart, ...
FASEB journal, 2017
572017
Testosterone enables growth and hypertrophy in fusion impaired myoblasts that display myotube atrophy: deciphering the role of androgen and IGF-I receptors
DC Hughes, CE Stewart, N Sculthorpe, HF Dugdale, F Yousefian, ...
Biogerontology 17, 619-639, 2016
562016
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