| Human skeletal muscle possesses an epigenetic memory of hypertrophy RA Seaborne, J Strauss, M Cocks, S Shepherd, TD O’Brien, ... Scientific reports 8 (1), 1898, 2018 | 292 | 2018 |
| Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake AP Sharples, DC Hughes, CS Deane, A Saini, C Selman, CE Stewart Aging cell 14 (4), 511-523, 2015 | 226 | 2015 |
| Does skeletal muscle have an ‘epi’‐memory? The role of epigenetics in nutritional programming, metabolic disease, aging and exercise AP Sharples, CE Stewart, RA Seaborne Aging cell 15 (4), 603-616, 2016 | 212 | 2016 |
| A systems-based investigation into vitamin D and skeletal muscle repair, regeneration, and hypertrophy DJ Owens, AP Sharples, I Polydorou, N Alwan, T Donovan, J Tang, ... American Journal of Physiology-Endocrinology and Metabolism, 2015 | 188 | 2015 |
| Fuel for the work required: a practical approach to amalgamating train‐low paradigms for endurance athletes SG Impey, KM Hammond, SO Shepherd, AP Sharples, C Stewart, M Limb, ... Physiological reports 4 (10), e12803, 2016 | 135 | 2016 |
| Comparative transcriptome and methylome analysis in human skeletal muscle anabolism, hypertrophy and epigenetic memory DC Turner, RA Seaborne, AP Sharples Scientific reports 9 (1), 4251, 2019 | 111 | 2019 |
| Factors affecting the structure and maturation of human tissue engineered skeletal muscle NRW Martin, SL Passey, DJ Player, A Khodabukus, RA Ferguson, ... Biomaterials 34 (23), 5759-5765, 2013 | 96 | 2013 |
| Modelling in vivo skeletal muscle ageing in vitro using three‐dimensional bioengineered constructs AP Sharples, DJ Player, NRW Martin, V Mudera, CE Stewart, MP Lewis Aging cell 11 (6), 986-995, 2012 | 85 | 2012 |
| DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity DC Turner, PP Gorski, MF Maasar, RA Seaborne, P Baumert, AD Brown, ... Scientific Reports 10 (1), 15360, 2020 | 84 | 2020 |
| An epigenetic clock for human skeletal muscle S Voisin, NR Harvey, LM Haupt, LR Griffiths, KJ Ashton, VG Coffey, ... Journal of cachexia, sarcopenia and muscle 11 (4), 887-898, 2020 | 83 | 2020 |
| C2 and C2C12 murine skeletal myoblast models of atrophic and hypertrophic potential: Relevance to disease and ageing? AP Sharples, N Al‐Shanti, CE Stewart Journal of cellular physiology 225 (1), 240-250, 2010 | 80 | 2010 |
| Methylome of human skeletal muscle after acute & chronic resistance exercise training, detraining & retraining RA Seaborne, J Strauss, M Cocks, S Shepherd, TD O’brien, ... Scientific data 5 (1), 1-9, 2018 | 77 | 2018 |
| Skeletal muscle cells possess a ‘memory’of acute early life TNF-α exposure: role of epigenetic adaptation AP Sharples, I Polydorou, DC Hughes, DJ Owens, TM Hughes, ... Biogerontology 17, 603-617, 2016 | 76 | 2016 |
| Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training B Egan, AP Sharples Physiological Reviews, 2023 | 70 | 2023 |
| Reduction of myoblast differentiation following multiple population doublings in mouse C2C12 cells: A model to investigate ageing? AP Sharples, N Al‐Shanti, MP Lewis, CE Stewart Journal of cellular biochemistry 112 (12), 3773-3785, 2011 | 68 | 2011 |
| The interplay between exercise metabolism, epigenetics, and skeletal muscle remodeling RA Seaborne, AP Sharples Exercise and sport sciences reviews 48 (4), 188-200, 2020 | 67 | 2020 |
| UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy RA Seaborne, DC Hughes, DC Turner, DJ Owens, LM Baehr, P Gorski, ... The Journal of physiology 597 (14), 3727-3749, 2019 | 66 | 2019 |
| Post‐exercise carbohydrate and energy availability induce independent effects on skeletal muscle cell signalling and bone turnover: implications for training adaptation KM Hammond, C Sale, W Fraser, J Tang, SO Shepherd, JA Strauss, ... The Journal of physiology 597 (18), 4779-4796, 2019 | 61 | 2019 |
| Transcriptomic and epigenetic regulation of disuse atrophy and the return to activity in skeletal muscle A Fisher, RA Seaborne, TM Hughes, A Gutteridge, CE Stewart, ... FASEB journal, 2017 | 57 | 2017 |
| Testosterone enables growth and hypertrophy in fusion impaired myoblasts that display myotube atrophy: deciphering the role of androgen and IGF-I receptors DC Hughes, CE Stewart, N Sculthorpe, HF Dugdale, F Yousefian, ... Biogerontology 17, 619-639, 2016 | 56 | 2016 |
David C. HughesAging & Metabolism Program, Oklahoma Medical Research FoundationVerified email at omrf.org
