|Extending healthy life span—from yeast to humans|
L Fontana, L Partridge, VD Longo
science 328 (5976), 321-326, 2010
|Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans|
BD Muegge, J Kuczynski, D Knights, JC Clemente, A González, ...
Science 332 (6032), 970-974, 2011
|Visceral fat adipokine secretion is associated with systemic inflammation in obese humans|
L Fontana, JC Eagon, ME Trujillo, PE Scherer, S Klein
Diabetes 56 (4), 1010-1013, 2007
|Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease|
S Klein, L Fontana, VL Young, AR Coggan, C Kilo, BW Patterson, ...
New England Journal of Medicine 350 (25), 2549-2557, 2004
|Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans|
L Fontana, TE Meyer, S Klein, JO Holloszy
Proceedings of the national Academy of Sciences 101 (17), 6659-6663, 2004
|Promoting Health and Longevity through Diet: from Model Organisms to Humans|
L Partridge, L Fontana
|Aging, adiposity, and calorie restriction|
L Fontana, S Klein
Jama 297 (9), 986-994, 2007
|Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population|
ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ...
Cell metabolism 19 (3), 407-417, 2014
|Caloric restriction in humans|
JO Holloszy, L Fontana
Experimental gerontology 42 (8), 709-712, 2007
|Long-term caloric restriction ameliorates the decline in diastolic function in humans|
TE Meyer, SJ Kovács, AA Ehsani, S Klein, JO Holloszy, L Fontana
Journal of the American College of Cardiology 47 (2), 398-402, 2006
|Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial|
Washington University School of Medicine CALERIE Group Weiss Edward P ...
The American journal of clinical nutrition 84 (5), 1033-1042, 2006
|Long‐term effects of calorie or protein restriction on serum IGF‐1 and IGFBP‐3 concentration in humans|
L Fontana, EP Weiss, DT Villareal, S Klein, JO Holloszy
Aging cell 7 (5), 681-687, 2008
|Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance|
J Yoshino, C Conte, L Fontana, B Mittendorfer, S Imai, KB Schechtman, ...
Cell metabolism 16 (5), 658-664, 2012
|Interventions to slow aging in humans: are we ready?|
VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ...
Aging cell 14 (4), 497-510, 2015
|Calorie restriction and cancer prevention: metabolic and molecular mechanisms|
VD Longo, L Fontana
Trends in pharmacological sciences 31 (2), 89-98, 2010
|Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults|
DT Villareal, BV Miller III, M Banks, L Fontana, DR Sinacore, S Klein
The American journal of clinical nutrition 84 (6), 1317-1323, 2006
|Bone mineral density response to caloric restriction–induced weight loss or exercise-induced weight loss: a randomized controlled trial|
DT Villareal, L Fontana, EP Weiss, SB Racette, K Steger-May, ...
Archives of internal medicine 166 (22), 2502-2510, 2006
|Fasting and cancer treatment in humans: A case series report|
FM Safdie, T Dorff, D Quinn, L Fontana, M Wei, C Lee, P Cohen, ...
Aging (Albany NY) 1 (12), 988, 2009
|Meal frequency and timing in health and disease|
MP Mattson, DB Allison, L Fontana, M Harvie, VD Longo, WJ Malaisse, ...
Proceedings of the National Academy of Sciences 111 (47), 16647-16653, 2014
|Calorie restriction and prevention of age‐associated chronic disease|
D Omodei, L Fontana
FEBS letters 585 (11), 1537-1542, 2011