| Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein P Desplats, HJ Lee, EJ Bae, C Patrick, E Rockenstein, L Crews, ... Proceedings of the National Academy of Sciences 106 (31), 13010-13015, 2009 | 1734 | 2009 |
| Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein P Desplats, HJ Lee, EJ Bae, C Patrick, E Rockenstein, L Crews, ... Proceedings of the National Academy of Sciences 106 (31), 13010-13015, 2009 | 1731 | 2009 |
| Molecular mechanisms of neurodegeneration in Alzheimer's disease L Crews, E Masliah Human molecular genetics 19 (R1), R12-R20, 2010 | 881 | 2010 |
| Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study MA Lemp, LA Crews, AJ Bron, GN Foulks, BD Sullivan Cornea 31 (5), 472-478, 2012 | 791 | 2012 |
| Effects of α-synuclein immunization in a mouse model of Parkinson’s disease E Masliah, E Rockenstein, A Adame, M Alford, L Crews, M Hashimoto, ... Neuron 46 (6), 857-868, 2005 | 710 | 2005 |
| Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer’s and Parkinson’s diseases M Hashimoto, E Rockenstein, L Crews, E Masliah Neuromolecular medicine 4, 21-35, 2003 | 664 | 2003 |
| Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model O Singer, RA Marr, E Rockenstein, L Crews, NG Coufal, FH Gage, ... Nature neuroscience 8 (10), 1343-1349, 2005 | 522 | 2005 |
| Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease E Masliah, E Rockenstein, M Mante, L Crews, B Spencer, A Adame, ... PloS one 6 (4), e19338, 2011 | 495 | 2011 |
| Aβ vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease E Masliah, L Hansen, A Adame, L Crews, F Bard, C Lee, P Seubert, ... Neurology 64 (1), 129-131, 2005 | 455 | 2005 |
| Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications BD Sullivan, LA Crews, EM Messmer, GN Foulks, KK Nichols, ... Acta ophthalmologica 92 (2), 161-166, 2014 | 435 | 2014 |
| Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of α-synucleinopathy L Crews, B Spencer, P Desplats, C Patrick, A Paulino, E Rockenstein, ... PloS one 5 (2), e9313, 2010 | 422 | 2010 |
| Deficiency in neuronal TGF-β signaling promotes neurodegeneration and Alzheimer’s pathology I Tesseur, K Zou, L Esposito, F Bard, E Berber, J Van Can, AH Lin, ... The Journal of clinical investigation 116 (11), 3060-3069, 2006 | 376 | 2006 |
| Neuroprotective effects of regulators of the glycogen synthase kinase-3β signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid … E Rockenstein, M Torrance, A Adame, M Mante, P Bar-On, JB Rose, ... Journal of Neuroscience 27 (8), 1981-1991, 2007 | 336 | 2007 |
| Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases IF Tsigelny, L Crews, P Desplats, GM Shaked, Y Sharikov, H Mizuno, ... PloS one 3 (9), e3135, 2008 | 328 | 2008 |
| Clinical utility of objective tests for dry eye disease: variability over time and implications for clinical trials and disease management BD Sullivan, LA Crews, B Sönmez, MF de la Paz, E Comert, ... Cornea 31 (9), 1000-1008, 2012 | 257 | 2012 |
| Neurological and neurodegenerative alterations in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy CW Shults, E Rockenstein, L Crews, A Adame, M Mante, G Larrea, ... Journal of Neuroscience 25 (46), 10689-10699, 2005 | 252 | 2005 |
| Progressive accumulation of amyloid‐β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations … E Pham, L Crews, K Ubhi, L Hansen, A Adame, A Cartier, D Salmon, ... The FEBS journal 277 (14), 3051-3067, 2010 | 246 | 2010 |
| Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis L Crews, A Adame, C Patrick, A DeLaney, E Pham, E Rockenstein, ... Journal of Neuroscience 30 (37), 12252-12262, 2010 | 214 | 2010 |
| Dynamics of α‐synuclein aggregation and inhibition of pore‐like oligomer development by β‐synuclein IF Tsigelny, P Bar‐On, Y Sharikov, L Crews, M Hashimoto, MA Miller, ... The FEBS journal 274 (7), 1862-1877, 2007 | 214 | 2007 |
| Role of α‐synuclein penetration into the membrane in the mechanisms of oligomer pore formation IF Tsigelny, Y Sharikov, W Wrasidlo, T Gonzalez, PA Desplats, L Crews, ... The FEBS journal 279 (6), 1000-1013, 2012 | 208 | 2012 |
Catriona JamiesonProfessor of Medicine and Chief, Division of Regenerative Medicine, UC San DiegoVerified email at ucsd.edu
