A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples ME Ackerman, B Moldt, RT Wyatt, AS Dugast, E McAndrew, S Tsoukas, ... Journal of immunological methods 366 (1-2), 8-19, 2011 | 468 | 2011 |
Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines AW Chung, M Ghebremichael, H Robinson, E Brown, I Choi, S Lane, ... Science translational medicine 6 (228), 228ra38-228ra38, 2014 | 443 | 2014 |
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity ME Ackerman, M Crispin, X Yu, K Baruah, AW Boesch, DJ Harvey, ... The Journal of clinical investigation 123 (5), 2183-2192, 2013 | 404 | 2013 |
Dissecting polyclonal vaccine-induced humoral immunity against HIV using systems serology AW Chung, MP Kumar, KB Arnold, WH Yu, MK Schoen, LJ Dunphy, ... Cell 163 (4), 988-998, 2015 | 370 | 2015 |
Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys DH Barouch, G Alter, T Broge, C Linde, ME Ackerman, EP Brown, ... Science 349 (6245), 320-324, 2015 | 335 | 2015 |
Polyfunctional HIV-specific antibody responses are associated with spontaneous HIV control ME Ackerman, A Mikhailova, EP Brown, KG Dowell, BD Walker, ... PLoS pathogens 12 (1), e1005315, 2016 | 284 | 2016 |
High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples EP Brown, AF Licht, AS Dugast, I Choi, C Bailey-Kellogg, G Alter, ... Journal of immunological methods 386 (1-2), 117-123, 2012 | 235 | 2012 |
Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition M Vaccari, SN Gordon, S Fourati, L Schifanella, NPM Liyanage, ... Nature medicine 22 (7), 762-770, 2016 | 217 | 2016 |
Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles EP Brown, KG Dowell, AW Boesch, E Normandin, AE Mahan, T Chu, ... Journal of immunological methods 443, 33-44, 2017 | 189 | 2017 |
A modular IgG-scFv bispecific antibody topology KD Orcutt, ME Ackerman, M Cieslewicz, E Quiroz, AL Slusarczyk, ... Protein Engineering, Design & Selection 23 (4), 221-228, 2010 | 144 | 2010 |
Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge T Bradley, J Pollara, S Santra, N Vandergrift, S Pittala, C Bailey-Kellogg, ... Nature communications 8 (1), 15711, 2017 | 142 | 2017 |
Protein-protein fusion catalyzed by sortase A DA Levary, R Parthasarathy, ET Boder, ME Ackerman PloS one 6 (4), e18342, 2011 | 142 | 2011 |
Stability and CDR composition biases enrich binder functionality landscapes BJ Hackel, ME Ackerman, SW Howland, KD Wittrup Journal of molecular biology 401 (1), 84-96, 2010 | 141 | 2010 |
Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV ME Ackerman, J Das, S Pittala, T Broge, C Linde, TJ Suscovich, EP Brown, ... Nature medicine 24 (10), 1590-1598, 2018 | 135 | 2018 |
Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function AW Chung, M Crispin, L Pritchard, H Robinson, MK Gorny, X Yu, ... Aids 28 (17), 2523-2530, 2014 | 126 | 2014 |
Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids ME Ackerman, D Pawlowski, KD Wittrup Molecular cancer therapeutics 7 (7), 2233-2240, 2008 | 125 | 2008 |
A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis AE Mahan, J Tedesco, K Dionne, K Baruah, HD Cheng, PL De Jager, ... Journal of immunological methods 417, 34-44, 2015 | 122 | 2015 |
Mapping functional humoral correlates of protection against malaria challenge following RTS, S/AS01 vaccination TJ Suscovich, JK Fallon, J Das, AR Demas, J Crain, CH Linde, A Michell, ... Science translational medicine 12 (553), eabb4757, 2020 | 119 | 2020 |
Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b ME Ackerman, AS Dugast, EG McAndrew, S Tsoukas, AF Licht, DJ Irvine, ... Journal of virology 87 (10), 5468-5476, 2013 | 118 | 2013 |
Highly avid magnetic bead capture: an efficient selection method for de novo protein engineering utilizing yeast surface display M Ackerman, D Levary, G Tobon, B Hackel, KD Orcutt, KD Wittrup Biotechnology progress 25 (3), 774-783, 2009 | 118 | 2009 |