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Wanyin Deng, Ph.D.
Wanyin Deng, Ph.D.
Michael Smith Laboratories, University of British Columbia
Verified email at msl.ubc.ca
Title
Cited by
Cited by
Year
Dissecting virulence: systematic and functional analyses of a pathogenicity island
W Deng, JL Puente, S Gruenheid, Y Li, BA Vallance, A Vázquez, J Barba, ...
Proceedings of the National Academy of Sciences 101 (10), 3597-3602, 2004
7312004
Assembly, structure, function and regulation of type III secretion systems
W Deng, NC Marshall, JL Rowland, JM McCoy, LJ Worrall, AS Santos, ...
Nature Reviews Microbiology 15 (6), 323-337, 2017
5242017
Locus of enterocyte effacement from Citrobacter rodentium: sequence analysis and evidence for horizontal transfer among attaching and effacing pathogens
W Deng, Y Li, BA Vallance, BB Finlay
Infection and Immunity 69 (10), 6323, 2001
2902001
Identification and characterization of NleA, a non‐LEE‐encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157: H7
S Gruenheid, I Sekirov, NA Thomas, W Deng, P O'Donnell, D Goode, Y Li, ...
Molecular Microbiology 51 (5), 1233-1249, 2004
2732004
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system
T Spreter, CK Yip, S Sanowar, I André, TG Kimbrough, M Vuckovic, ...
Nature Structural & Molecular Biology 16 (5), 468-476, 2009
2362009
Attaching and effacing pathogen‐induced tight junction disruption in vivo
JA Guttman, Y Li, ME Wickham, W Deng, AW Vogl, BB Finlay
Cellular Microbiology 8 (4), 634-645, 2006
2292006
Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium
BA Vallance, W Deng, K Jacobson, BB Finlay
Infection and Immunity 71 (6), 3443, 2003
2292003
Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice
W Deng, BA Vallance, Y Li, JL Puente, BB Finlay
Molecular Microbiology 48 (1), 95-115, 2003
2192003
Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens
W Deng, Y Li, PR Hardwidge, EA Frey, RA Pfuetzner, S Lee, S Gruenheid, ...
Infection and Immunity 73 (4), 2135, 2005
2132005
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice
MA Khan, C Ma, LA Knodler, Y Valdez, CM Rosenberger, W Deng, ...
Infection and Immunity 74 (5), 2522, 2006
1942006
A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA
J Barba, VH Bustamante, MA Flores-Valdez, W Deng, BB Finlay, ...
Journal of Bacteriology 187 (23), 7918, 2005
1842005
Bacterial effector binding to ribosomal protein s3 subverts NF-κB function
X Gao, F Wan, K Mateo, E Callegari, D Wang, W Deng, J Puente, F Li, ...
PLoS Pathogens 5 (12), e1000708, 2009
1772009
Structural analysis of a prototypical ATPase from the type III secretion system
R Zarivach, M Vuckovic, W Deng, BB Finlay, NCJ Strynadka
Nature Structural & Molecular Biology 14 (2), 131-137, 2007
1772007
Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection
BA Vallance, W Deng, LA Knodler, BB Finlay
Infection and Immunity 70 (4), 2070, 2002
1692002
Aquaporins contribute to diarrhoea caused by attaching and effacing bacterial pathogens
JA Guttman, FN Samji, Y Li, W Deng, A Lin, BB Finlay
Cellular Microbiology 9 (1), 131-141, 2007
1632007
Agrobacterium VirD2 protein interacts with plant host cyclophilins
W Deng, L Chen, DW Wood, T Metcalfe, X Liang, MP Gordon, L Comai, ...
Proceedings of the National Academy of Sciences 95 (12), 7040-7045, 1998
1591998
Role of inflammasomes in host defense against Citrobacter rodentium infection
Z Liu, MH Zaki, P Vogel, P Gurung, BB Finlay, W Deng, M Lamkanfi, ...
Journal of Biological chemistry 287 (20), 16955-16964, 2012
1582012
Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS
R Zarivach, W Deng, M Vuckovic, HB Felise, HV Nguyen, SI Miller, ...
Nature 453 (7191), 124-127, 2008
1562008
Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map)
C Ma, ME Wickham, JA Guttman, W Deng, J Walker, KL Madsen, ...
Cellular Microbiology 8 (10), 1669-1686, 2006
1552006
Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body
LJ Worrall, C Hong, M Vuckovic, W Deng, JRC Bergeron, DD Majewski, ...
Nature 540 (7634), 597-601, 2016
1462016
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