Jeremy C. Mottram
Jeremy C. Mottram
Professor in Pathogen Biology
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Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 8 (4), 445-544, 2012
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
autophagy 12 (1), 1-222, 2016
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
NM El-Sayed, PJ Myler, DC Bartholomeu, D Nilsson, G Aggarwal, ...
Science 309 (5733), 409, 2005
The genome of the kinetoplastid parasite, Leishmania major
AC Ivens, CS Peacock, EA Worthey, L Murphy, G Aggarwal, M Berriman, ...
Science 309 (5733), 436, 2005
Chagas disease in Latin America: an epidemiological update based on 2010 estimates
World Health Organization
Weekly Epidemiological Record= Relevé épidémiologique hebdomadaire 90 (06 …, 2015
Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis
JM Carlton, RP Hirt, JC Silva, AL Delcher, M Schatz, Q Zhao, JR Wortman, ...
Science 315 (5809), 207-212, 2007
Comparative genomic analysis of three Leishmania species that cause diverse human disease
CS Peacock, K Seeger, D Harris, L Murphy, JC Ruiz, MA Quail, N Peters, ...
Nature genetics 39 (7), 839-847, 2007
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania
MB Rogers, JD Hilley, NJ Dickens, J Wilkes, PA Bates, DP Depledge, ...
Genome research 21 (12), 2129-2142, 2011
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance
T Downing, H Imamura, S Decuypere, TG Clark, GH Coombs, JA Cotton, ...
Genome research 21 (12), 2143-2156, 2011
Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi
M Parsons, EA Worthey, PN Ward, JC Mottram
BMC genomics 6 (1), 1-19, 2005
Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets
GH Coombs, DE Goldberg, M Klemba, C Berry, J Kay, JC Mottram
TRENDS in Parasitology 17 (11), 532-537, 2001
Leishmania mexicana cysteine proteinase-deficient mutants have attenuated virulence for mice and potentiate a Th1 response
J Alexander, GH Coombs, JC Mottram
The Journal of Immunology 161 (12), 6794-6801, 1998
Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors
M Knockaert, N Gray, E Damiens, YT Chang, P Grellier, K Grant, ...
Chemistry & biology 7 (6), 411-422, 2000
Cysteine peptidases as virulence factors of Leishmania
JC Mottram, GH Coombs, J Alexander
Current opinion in microbiology 7 (4), 375-381, 2004
Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors
JC Mottram, AE Souza, JE Hutchison, R Carter, MJ Frame, GH Coombs
Proceedings of the National Academy of Sciences 93 (12), 6008-6013, 1996
Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
S Khare, AS Nagle, A Biggart, YH Lai, F Liang, LC Davis, SW Barnes, ...
Nature 537 (7619), 229-233, 2016
Protein kinases as drug targets in trypanosomes and Leishmania
C Naula, M Parsons, JC Mottram
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1754 (1-2), 151-159, 2005
Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major
S Besteiro, RAM Williams, LS Morrison, GH Coombs, JC Mottram
Journal of Biological Chemistry 281 (16), 11384-11396, 2006
Cysteine proteinases of parasitic protozoa
MJ North, JC Mottram, GH Coombs
Parasitology Today 6 (8), 270-275, 1990
Protein turnover and differentiation in Leishmania
S Besteiro, RAM Williams, GH Coombs, JC Mottram
International journal for parasitology 37 (10), 1063-1075, 2007
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