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Stephen Yant
Stephen Yant
Director, Gilead Sciences
Verified email at gilead.com
Title
Cited by
Cited by
Year
Sarcoma derived from cultured mesenchymal stem cells
J Tolar, AJ Nauta, MJ Osborn, A Panoskaltsis Mortari, RT McElmurry, ...
Stem cells 25 (2), 371-379, 2007
8112007
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
SR Yant, L Meuse, W Chiu, Z Ivics, Z Izsvak, MA Kay
Nature genetics 25 (1), 35-41, 2000
6292000
Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo
H Nakai, SR Yant, TA Storm, S Fuess, L Meuse, MA Kay
Journal of virology 75 (15), 6969-6976, 2001
5622001
The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9
B Akache, D Grimm, K Pandey, SR Yant, H Xu, MA Kay
Journal of virology 80 (19), 9831-9836, 2006
5522006
High-resolution genome-wide mapping of transposon integration in mammals
SR Yant, X Wu, Y Huang, B Garrison, SM Burgess, MA Kay
Molecular and cellular biology, 2005
3812005
Antiviral activity of bictegravir (GS-9883), a novel potent HIV-1 integrase strand transfer inhibitor with an improved resistance profile
M Tsiang, GS Jones, J Goldsmith, A Mulato, D Hansen, E Kan, L Tsai, ...
Antimicrobial agents and chemotherapy 60 (12), 7086-7097, 2016
2802016
Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo
SR Yant, A Ehrhardt, JG Mikkelsen, L Meuse, T Pham, MA Kay
Nature biotechnology 20 (10), 999-1005, 2002
2462002
Clinical targeting of HIV capsid protein with a long-acting small molecule
JO Link, MS Rhee, WC Tse, J Zheng, JR Somoza, W Rowe, R Begley, ...
Nature 584 (7822), 614-618, 2020
2422020
Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver
ZY Chen, SR Yant, CY He, L Meuse, S Shen, MA Kay
Molecular Therapy 3 (3), 403-410, 2001
2332001
Distinct pathways of genomic progression to benign and malignant tumors of the liver
AD Tward, KD Jones, S Yant, ST Cheung, ST Fan, X Chen, MA Kay, ...
Proceedings of the National Academy of Sciences 104 (37), 14771-14776, 2007
2232007
Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid
K Peng, W Muranyi, B Glass, V Laketa, SR Yant, L Tsai, T Cihlar, B Müller, ...
Elife 3, e04114, 2014
1962014
Helper-independent Sleeping Beauty transposon–transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo
JG Mikkelsen, SR Yant, L Meuse, Z Huang, H Xu, MA Kay
Molecular Therapy 8 (4), 654-665, 2003
1882003
Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells
SR Yant, J Park, Y Huang, JG Mikkelsen, MA Kay
Molecular and cellular biology 24 (20), 9239-9247, 2004
1862004
High affinity YY1 binding motifs: identification of two core types (ACAT and CCAT) and distribution of potential binding sites within the human β globin cluster
SR Yant, W Zhu, D Millinoff, JL Slightom, M Goodman, DL Gumucio
Nucleic acids research 23 (21), 4353-4362, 1995
1831995
In vivo correction of murine tyrosinemia type I by DNA-mediated transposition
E Montini, PK Held, M Noll, N Morcinek, M Al-Dhalimy, M Finegold, ...
Molecular Therapy 6 (6), 759-769, 2002
1722002
Site-directed transposon integration in human cells
SR Yant, Y Huang, B Akache, MA Kay
Nucleic acids research 35 (7), e50, 2007
1642007
Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer
S Ortiz-Urda, Q Lin, SR Yant, D Keene, MA Kay, PA Khavari
Gene therapy 10 (13), 1099-1104, 2003
1612003
Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells
M Balakrishnan, SR Yant, L Tsai, C O’Sullivan, RA Bam, A Tsai, ...
PloS one 8 (9), e74163, 2013
1522013
Tenofovir alafenamide is not a substrate for renal organic anion transporters (OATs) and does not exhibit OAT-dependent cytotoxicity
RA Bam, SR Yant, T Cihlar
Antiviral therapy 19 (7), 687-692, 2014
1292014
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model
SR Yant, A Mulato, D Hansen, WC Tse, A Niedziela-Majka, JR Zhang, ...
Nature medicine 25 (9), 1377-1384, 2019
1182019
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