Luca Gattinoni
Luca Gattinoni
Principal Investigator, National Cancer Institute
Verified email at mail.nih.gov - Homepage
TitleCited byYear
Adoptive immunotherapy for cancer: building on success
L Gattinoni, DJ Powell, SA Rosenberg, NP Restifo
Nature Reviews Immunology 6 (5), 383-393, 2006
10622006
A human memory T cell subset with stem cell-like properties
L Gattinoni, E Lugli, Y Ji, Z Pos, CM Paulos, MF Quigley, JR Almeida, ...
Nature medicine 17 (10), 1290-1297, 2011
9232011
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
L Gattinoni, SE Finkelstein, CA Klebanoff, PA Antony, DC Palmer, ...
Journal of Experimental Medicine 202 (7), 907-912, 2005
8122005
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells
L Gattinoni, CA Klebanoff, DC Palmer, C Wrzesinski, K Kerstann, Z Yu, ...
The Journal of clinical investigation 115 (6), 1616-1626, 2005
7772005
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
CA Klebanoff, L Gattinoni, P Torabi-Parizi, K Kerstann, AR Cardones, ...
Proceedings of the National Academy of Sciences 102 (27), 9571-9576, 2005
7362005
Tumor-specific Th17-polarized cells eradicate large established melanoma
P Muranski, A Boni, PA Antony, L Cassard, KR Irvine, A Kaiser, ...
Blood 112 (2), 362-373, 2008
7172008
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
L Gattinoni, XS Zhong, DC Palmer, Y Ji, CS Hinrichs, Z Yu, C Wrzesinski, ...
Nature medicine 15 (7), 808-813, 2009
5572009
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
CA Klebanoff, SE Finkelstein, DR Surman, MK Lichtman, L Gattinoni, ...
Proceedings of the National Academy of Sciences 101 (7), 1969-1974, 2004
4862004
CD8+ T‐cell memory in tumor immunology and immunotherapy
CA Klebanoff, L Gattinoni, NP Restifo
Immunological reviews 211 (1), 214-224, 2006
4382006
IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy
CS Hinrichs, R Spolski, CM Paulos, L Gattinoni, KW Kerstann, DC Palmer, ...
Blood 111 (11), 5326-5333, 2008
3222008
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling
CM Paulos, C Wrzesinski, A Kaiser, CS Hinrichs, M Chieppa, L Cassard, ...
The Journal of clinical investigation 117 (8), 2197-2204, 2007
3182007
Paths to stemness: building the ultimate antitumour T cell
L Gattinoni, CA Klebanoff, NP Restifo
Nature Reviews Cancer 12 (10), 671-684, 2012
3092012
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
M Sukumar, J Liu, Y Ji, M Subramanian, JG Crompton, Z Yu, ...
The Journal of clinical investigation 123 (10), 4479-4488, 2013
3072013
Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity
CS Hinrichs, ZA Borman, L Cassard, L Gattinoni, R Spolski, Z Yu, ...
Proceedings of the National Academy of Sciences, pnas. 0907448106, 2009
3002009
Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature
P Muranski, ZA Borman, SP Kerkar, CA Klebanoff, Y Ji, L Sanchez-Perez, ...
Immunity 35 (6), 972-985, 2011
2772011
High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation
Y Zhao, Z Zheng, CJ Cohen, L Gattinoni, DC Palmer, NP Restifo, ...
Molecular therapy 13 (1), 151-159, 2006
2222006
Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells
C Wrzesinski, CM Paulos, A Kaiser, P Muranski, DC Palmer, L Gattinoni, ...
Journal of immunotherapy (Hagerstown, Md.: 1997) 33 (1), 1, 2010
2112010
Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy
CS Hinrichs, ZA Borman, L Gattinoni, Z Yu, WR Burns, J Huang, ...
Blood 117 (3), 808-814, 2011
2082011
Safety and efficacy of two different doses of capecitabine in the treatment of advanced breast cancer in older women
E Bajetta, G Procopio, L Celio, L Gattinoni, S Della Torre, L Mariani, ...
Journal of clinical oncology 23 (10), 2155-2161, 2005
2072005
BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis
R Roychoudhuri, K Hirahara, K Mousavi, D Clever, CA Klebanoff, ...
Nature 498 (7455), 506-510, 2013
2032013
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