Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and-independent pathways H Hochrein, B Schlatter, M O'Keeffe, C Wagner, F Schmitz, M Schiemann, ... Proceedings of the National Academy of Sciences 101 (31), 11416-11421, 2004 | 589 | 2004 |
The DNA sugar backbone 2′ deoxyribose determines toll-like receptor 9 activation T Haas, J Metzger, F Schmitz, A Heit, T Müller, E Latz, H Wagner Immunity 28 (3), 315-323, 2008 | 410 | 2008 |
Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and-independent pathways K Yasuda, P Yu, CJ Kirschning, B Schlatter, F Schmitz, A Heit, S Bauer, ... The Journal of Immunology 174 (10), 6129-6136, 2005 | 333 | 2005 |
Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice B Spies, H Hochrein, M Vabulas, K Huster, DH Busch, F Schmitz, A Heit, ... The Journal of Immunology 171 (11), 5908-5912, 2003 | 275 | 2003 |
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells F Schmitz, A Heit, S Dreher, K Eisenächer, J Mages, T Haas, A Krug, ... European journal of immunology 38 (11), 2981-2992, 2008 | 254 | 2008 |
CpG-DNA aided cross-priming by cross-presenting B cells A Heit, KM Huster, F Schmitz, M Schiemann, DH Busch, H Wagner The Journal of Immunology 172 (3), 1501-1507, 2004 | 198 | 2004 |
Interferon‐regulatory‐factor 1 controls Toll‐like receptor 9‐mediated IFN‐β production in myeloid dendritic cells F Schmitz, A Heit, S Guggemoos, A Krug, J Mages, M Schiemann, H Adler, ... European journal of immunology 37 (2), 315-327, 2007 | 197 | 2007 |
Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2. 1-specific TCR J Kuball, FW Schmitz, RH Voss, EA Ferreira, R Engel, P Guillaume, ... Immunity 22 (1), 117-129, 2005 | 194 | 2005 |
Antigen co‐encapsulated with adjuvants efficiently drive protective T cell immunity A Heit, F Schmitz, T Haas, DH Busch, H Wagner European journal of immunology 37 (8), 2063-2074, 2007 | 186 | 2007 |
CpG motif‐independent activation of TLR9 upon endosomal translocation of “natural” phosphodiester DNA K Yasuda, M Rutz, B Schlatter, J Metzger, PB Luppa, F Schmitz, T Haas, ... European journal of immunology 36 (2), 431-436, 2006 | 175 | 2006 |
A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses V Litvak, AV Ratushny, AE Lampano, F Schmitz, AC Huang, A Raman, ... Nature 490 (7420), 421-425, 2012 | 167 | 2012 |
Control of dual‐specificity phosphatase‐1 expression in activated macrophages by IL‐10 M Hammer, J Mages, H Dietrich, F Schmitz, F Striebel, PJ Murray, ... European journal of immunology 35 (10), 2991-3001, 2005 | 162 | 2005 |
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection C Schliehe, EK Flynn, B Vilagos, U Richson, S Swaminathan, B Bosnjak, ... Nature immunology 16 (1), 67-74, 2015 | 133 | 2015 |
Protective CD8 T cell immunity triggered by CpG-protein conjugates competes with the efficacy of live vaccines A Heit, F Schmitz, M O’Keeffe, C Staib, DH Busch, H Wagner, KM Huster The Journal of Immunology 174 (7), 4373-4380, 2005 | 126 | 2005 |
Vaccination establishes clonal relatives of germinal center T cells in the blood of humans A Heit, F Schmitz, S Gerdts, B Flach, MS Moore, JA Perkins, HS Robins, ... Journal of Experimental Medicine 214 (7), 2139-2152, 2017 | 113 | 2017 |
Transcriptional activation induced in macrophages by Toll‐like receptor (TLR) ligands: from expression profiling to a model of TLR signaling F Schmitz, J Mages, A Heit, R Lang, H Wagner European journal of immunology 34 (10), 2863-2873, 2004 | 110 | 2004 |
Insulin-like growth factor-I serum concentrations and patterns of insulin-like growth factor binding proteins in patients with chronic liver disease JG Scharf, F Schmitz, J Frystyk, C Skjaerbaek, H Moesus, WF Blum, ... Journal of hepatology 25 (5), 689-699, 1996 | 86 | 1996 |
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses DE Zak, F Schmitz, ES Gold, AH Diercks, JJ Peschon, JS Valvo, ... Proceedings of the National Academy of Sciences 108 (28), 11536-11541, 2011 | 76 | 2011 |
Avadomide monotherapy in relapsed/refractory DLBCL: safety, efficacy, and a predictive gene classifier C Carpio, R Bouabdallah, L Ysebaert, JM Sancho, G Salles, R Cordoba, ... Blood, The Journal of the American Society of Hematology 135 (13), 996-1007, 2020 | 57 | 2020 |
The IFN regulatory factor 7‐dependent type I IFN response is not essential for early resistance against murine cytomegalovirus infection C Steinberg, K Eisenächer, O Gross, W Reindl, F Schmitz, J Ruland, ... European journal of immunology 39 (4), 1007-1018, 2009 | 55 | 2009 |