Richard Boucher
Richard Boucher
Professor of Medicine, University of NC at Chapel Hill
Verified email at - Homepage
Cited by
Cited by
Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients
D Worlitzsch, R Tarran, M Ulrich, U Schwab, A Cekici, KC Meyer, P Birrer, ...
The Journal of clinical investigation 109 (3), 317-325, 2002
Mucus clearance as a primary innate defense mechanism for mammalian airways
MR Knowles, RC Boucher
The Journal of clinical investigation 109 (5), 571-577, 2002
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
H Matsui, BR Grubb, R Tarran, SH Randell, JT Gatzy, CW Davis, ...
Cell 95 (7), 1005-1015, 1998
CFTR as a cAMP-dependent regulator of sodium channels
MJ Stutts, CM Canessa, JC Olsen, M Hamrick, JA Cohn, BC Rossier, ...
Science 269 (5225), 847-850, 1995
An animal model for cystic fibrosis made by gene targeting
JN Snouwaert, KK Brigman, AM Latour, NN Malouf, RC Boucher, ...
Science 257 (5073), 1083-1088, 1992
Early death due to defective neonatal lung liquid clearance in α ENaC-deficient mice
E Hummler, P Barker, J Gatzy, F Beermann, C Verdumo, A Schmidt, ...
Nature genetics 12 (3), 325-328, 1996
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice
M Mall, BR Grubb, JR Harkema, WK O'Neal, RC Boucher
Nature medicine 10 (5), 487-493, 2004
Submucosal glands are the predominant site of CFTR expression in the human bronchus
JF Engelhardt, JR Yankaskas, SA Ernst, Y Yang, CR Marino, RC Boucher, ...
Nature genetics 2 (3), 240-248, 1992
Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.
B Sarkadi, EM Price, RC Boucher, UA Germann, GA Scarborough
Journal of Biological Chemistry 267 (7), 4854-4858, 1992
New concepts of the pathogenesis of cystic fibrosis lung disease
RC Boucher
European Respiratory Journal 23 (1), 146-158, 2004
Mucus clearance and lung function in cystic fibrosis with hypertonic saline
SH Donaldson, WD Bennett, KL Zeman, MR Knowles, R Tarran, ...
New England Journal of Medicine 354 (3), 241-250, 2006
Increased bioelectric potential difference across respiratory epithelia in cystic fibrosis
M Knowles, J Gatzy, R Boucher
New England Journal of Medicine 305 (25), 1489-1495, 1981
A controlled study of adenoviral-vector–mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
MR Knowles, KW Hohneker, Z Zhou, JC Olsen, TL Noah, PC Hu, ...
New England Journal of Medicine 333 (13), 823-831, 1995
Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation.
RC Boucher, MJ Stutts, MR Knowles, L Cantley, JT Gatzy
The Journal of clinical investigation 78 (5), 1245-1252, 1986
Mechanisms of release of nucleotides and integration of their action as P2X-and P2Y-receptor activating molecules
ER Lazarowski, RC Boucher, TK Harden
Molecular pharmacology 64 (4), 785-795, 2003
Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis
SS Yoon, RF Hennigan, GM Hilliard, UA Ochsner, K Parvatiyar, ...
Developmental cell 3 (4), 593-603, 2002
A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia
B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, ...
Science 337 (6097), 937-941, 2012
SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract
YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon III, ...
Cell 182 (2), 429-446. e14, 2020
Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology
L Zhang, ME Peeples, RC Boucher, PL Collins, RJ Pickles
Journal of virology 76 (11), 5654-5666, 2002
Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis
MR Knowles, LL Clarke, RC Boucher
New England Journal of Medicine 325 (8), 533-538, 1991
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