Lymphocyte-activation gene 3 (LAG3): The next immune checkpoint receptor E Ruffo, RC Wu, TC Bruno, CJ Workman, DAA Vignali Seminars in immunology 42, 101305, 2019 | 244 | 2019 |
Germline hypomorphic CARD11 mutations in severe atopic disease CA Ma, JR Stinson, Y Zhang, JK Abbott, MA Weinreich, PJ Hauk, ... Nature genetics 49 (8), 1192-1201, 2017 | 196 | 2017 |
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 E Ruffo, V Malacarne, SE Larsen, R Das, L Patrussi, C Wülfing, C Biskup, ... Science translational medicine 8 (321), 321ra7-321ra7, 2016 | 47 | 2016 |
The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness E Rainero, C Cianflone, PE Porporato, F Chianale, V Malacarne, V Bettio, ... Plos one 9 (6), e97144, 2014 | 39 | 2014 |
Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting E Ruffo, AA Butchy, Y Tivon, V So, M Kvorjak, A Parikh, EL Adams, ... Nature Communications 14 (1), 2463, 2023 | 23 | 2023 |
Identification of a novel DGKα inhibitor for XLP-1 therapy by virtual screening S Velnati, E Ruffo, A Massarotti, M Talmon, KSS Varma, A Gesu, LG Fresu, ... European journal of medicinal chemistry 164, 378-390, 2019 | 23 | 2019 |
Conditional control of universal CAR T cells by cleavable OFF-switch adaptors M Kvorjak, E Ruffo, Y Tivon, V So, A Parikh, A Deiters, J Lohmueller ACS Synthetic Biology 12 (10), 2996-3007, 2023 | 3 | 2023 |
Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction S Velnati, S Centonze, G Rossino, B Purghè, A Antona, L Racca, S Mula, ... Frontiers in Immunology 14, 1043603, 2023 | 3 | 2023 |
Preclinical development of universal SNAP-CAR T cell therapy E Ruffo, M Kvorjak, E Adams, J Lohmueller The Journal of Immunology 206 (1_Supplement), 67.11-67.11, 2021 | 1 | 2021 |
CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under control of antigen sensing in microwell arrays Y Cho, M Laird, T Bishop, R Li, E Ruffo, J Lohmueller, IK Zervantonakis bioRxiv, 2024.03. 14.585033, 2024 | | 2024 |
299 SNAP CAR T cells for programmable antigen targeting E Ruffo, V So, M Kvorjak, OJ Finn, A Deiters, J Lohmueller Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
Pre-assembled universal SNAP-CARs show potent anti-tumor function E Ruffo, M Kvorjak, E Adams, J Lohmueller The Journal of Immunology 208 (1_Supplement), 63.09-63.09, 2022 | | 2022 |
Germline hypomorphic CARD11 mutations in severe atopic disease (vol 49, pg 1192, 2017) CA Ma, JR Stinson, Y Zhang, JK Abbott, MA Weinreich, PJ Hauk, ... Nature Genetics 49 (11), 1661-1661, 2017 | | 2017 |
Germline hypomorphic, dominant interfering CARD11 mutations drive severe atopic disease AL Snow, C Ma, JR Stinson, Y Zhang, JK Abbott, MA Weinrich, PJ Hauk, ... The Journal of Immunology 198 (1_Supplement), 59.6-59.6, 2017 | | 2017 |
GERMLINE HYPOMORPHIC, DOMINANT NEGATIVE CARD11 MUTATIONS IN SEVERE ATOPIC DISEASE. CA Ma, JR Stinson, Y Zhang, JK Abbott, PJ Hauk, PR Reynolds, ... JOURNAL OF CLINICAL IMMUNOLOGY 37 (2), 243-243, 2017 | | 2017 |
Regulation of Diacylglycerol Kinase alpha in controlling activated T cell fate E Ruffo Università del Piemonte Orientale, 2017 | | 2017 |
Regulation of Diacylglycerol Kinase alpha in controlling activated T cell fate R Elisa | | 2017 |
NOVEL DIACYLGLYCEROL KINASE ALPHA INHIBITORS FOR X-LINKED LYMPHOPROLIFERATIVE DISEASE 1 THERAPY G Baldanzi, S Velnati, A Massarotti, E Ruffo, GC Tron, S Andrew, ... SIB 2017, 2017 | | 2017 |
INHIBITION OF DIACYLGLYCEROL KINASE ALPHA RESTORES SENSITIVITY TO TCR-INDUCED CELL DEATH AND LESSENS IMMUNOPATHOLOGY IN A MURINE MODEL OF XLP-ASSOCIATED HEMOPHAGOCYTIC … KE Nichols, E Ruffo, V Malacarne, S Larsen, R Das, L Patrussi, ... PEDIATRIC BLOOD & CANCER 62, S134-S134, 2015 | | 2015 |
Sintesi e caratterizzazione di nuovi inibitori di DGKα V Malacarne, E Ruffo, A Massarotti, G Baldanzi, GC Tron, A Graziani ., 2014 | | 2014 |