| Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus patients P Coit, M Jeffries, N Altorok, MG Dozmorov, KA Koelsch, JD Wren, ... Journal of autoimmunity 43, 78-84, 2013 | 318 | 2013 |
| COVID-19: A review of therapeutic strategies and vaccine candidates V Izda, MA Jeffries, AH Sawalha Clinical Immunology 222, 108634, 2021 | 301 | 2021 |
| Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus M Jeffries, M Dozmorov, Y Tang, JT Merrill, JD Wren, AH Sawalha Epigenetics 6 (5), 593-601, 2011 | 247 | 2011 |
| Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients AH Sawalha, M Jeffries, R Webb, Q Lu, G Gorelik, D Ray, J Osban, ... Genes & Immunity 9 (4), 368-378, 2008 | 162 | 2008 |
| Genome‐wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage MA Jeffries, M Donica, LW Baker, ME Stevenson, AC Annan, ... Arthritis & rheumatology 66 (10), 2804-2815, 2014 | 161 | 2014 |
| Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells P Coit, P Renauer, MA Jeffries, JT Merrill, WJ McCune, ... Journal of autoimmunity 61, 29-35, 2015 | 123 | 2015 |
| Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic … R Webb, JD Wren, M Jeffries, JA Kelly, KM Kaufman, Y Tang, MB Frank, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 100 | 2009 |
| Uric acid directly promotes human T-cell activation R Webb, M Jeffries, AH Sawalha The American journal of the medical sciences 337 (1), 23-27, 2009 | 92 | 2009 |
| DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus P Renauer, P Coit, MA Jeffries, JT Merrill, WJ McCune, ... Lupus science & medicine 2 (1), e000101, 2015 | 88 | 2015 |
| Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve? MA Jeffries, AH Sawalha Expert review of clinical immunology 11 (1), 45-58, 2015 | 83 | 2015 |
| Epigenetics in systemic lupus erythematosus: leading the way for specific therapeutic agents MA Jeffries, AH Sawalha International journal of clinical rheumatology 6 (4), 423, 2011 | 82 | 2011 |
| Haemolytic anaemia in a multi-ethnic cohort of lupus patients: a clinical and serological perspective M Jeffries, F Hamadeh, T Aberle, S Glenn, DL Kamen, JA Kelly, ... Lupus 17 (8), 739-743, 2008 | 77 | 2008 |
| Epigenetics and bone remodeling A Husain, MA Jeffries Current osteoporosis reports 15, 450-458, 2017 | 76 | 2017 |
| Defective DNA methylation and CD70 overexpression in CD4+ T cells in MRL/lpr lupus‐prone mice AH Sawalha, M Jeffries European journal of immunology 37 (5), 1407-1413, 2007 | 70 | 2007 |
| Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse KA Koelsch, R Webb, M Jeffries, MG Dozmorov, MB Frank, JM Guthridge, ... Journal of autoimmunity 41, 168-174, 2013 | 62 | 2013 |
| Genome‐wide DNA methylation study identifies significant epigenomic changes in osteoarthritic subchondral bone and similarity to overlying cartilage MA Jeffries, M Donica, LW Baker, ME Stevenson, AC Annan, ... Arthritis & rheumatology 68 (6), 1403-1414, 2016 | 60 | 2016 |
| Identification of cartilage microbial DNA signatures and associations with knee and hip osteoarthritis CM Dunn, C Velasco, A Rivas, M Andrews, C Garman, PB Jacob, ... Arthritis & Rheumatology 72 (7), 1111-1122, 2020 | 59 | 2020 |
| Osteoarthritis year in review 2018: genetics and epigenetics MA Jeffries Osteoarthritis and cartilage 27 (3), 371-377, 2019 | 57 | 2019 |
| The epigenomic landscape in osteoarthritis TC Simon, MA Jeffries Current rheumatology reports 19, 1-10, 2017 | 48 | 2017 |
| Epigenetic editing: How cutting-edge targeted epigenetic modification might provide novel avenues for autoimmune disease therapy MA Jeffries Clinical Immunology 196, 49-58, 2018 | 41 | 2018 |
Amr SawalhaProfessor, University of PittsburghVerified email at pitt.edu
