Alexander Cameron
Alexander Cameron
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Overcoming the challenges of membrane protein crystallography
EP Carpenter, K Beis, AD Cameron, S Iwata
Current opinion in structural biology 18 (5), 581-586, 2008
Structure and molecular mechanism of a nucleobase–cation–symport-1 family transporter
S Weyand, T Shimamura, S Yajima, S Suzuki, O Mirza, K Krusong, ...
Science 322 (5902), 709-713, 2008
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
T Hino, T Arakawa, H Iwanari, T Yurugi-Kobayashi, C Ikeda-Suno, ...
Nature 482 (7384), 237-240, 2012
Crystal structure of a prokaryotic homologue of the mammalian oligopeptide–proton symporters, PepT1 and PepT2
S Newstead, D Drew, AD Cameron, VLG Postis, X Xia, PW Fowler, ...
The EMBO journal 30 (2), 417-426, 2011
Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1
T Shimamura, S Weyand, O Beckstein, NG Rutherford, JM Hadden, ...
Science 328 (5977), 470-473, 2010
Crystal structure of human glyoxalase I—evidence for gene duplication and 3D domain swapping
AD Cameron, B Olin, M Ridderström, B Mannervik, TA Jones
The EMBO journal 16 (12), 3386-3395, 1997
Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT
NJ Hu, S Iwata, AD Cameron, D Drew
Nature 478 (7369), 408-411, 2011
A two-domain elevator mechanism for sodium/proton antiport
C Lee, HJ Kang, C von Ballmoos, S Newstead, P Uzdavinys, DL Dotson, ...
Nature 501 (7468), 573-577, 2013
Alternating access mechanism in the POT family of oligopeptide transporters
N Solcan, J Kwok, PW Fowler, AD Cameron, D Drew, S Iwata, ...
The EMBO journal 31 (16), 3411-3421, 2012
Crystal structure of the anion exchanger domain of human erythrocyte band 3
T Arakawa, T Kobayashi-Yurugi, Y Alguel, H Iwanari, H Hatae, M Iwata, ...
Science 350 (6261), 680-684, 2015
Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography
J Foadi, P Aller, Y Alguel, A Cameron, D Axford, RL Owen, W Armour, ...
Acta Crystallographica Section D: Biological Crystallography 69 (8), 1617-1632, 2013
Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue
AD Cameron, M Ridderström, B Olin, B Mannervik
Structure 7 (9), 1067-1078, 1999
1, 4, 5, 6-tetrahydropyrrolo [3, 4-c] pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile
D Fancelli, J Moll, M Varasi, R Bravo, R Artico, D Berta, S Bindi, ...
Journal of medicinal chemistry 49 (24), 7247-7251, 2006
Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 Å resolution: insights into a new family of kinase structures
JA Sigrell, AD Cameron, TA Jones, SL Mowbray
Structure 6 (2), 183-193, 1998
Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate
AD Cameron, I Sinning, G L'Hermite, B Olin, PG Board, B Mannervik, ...
Structure 3 (7), 717-727, 1995
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
P Pevarello, MG Brasca, R Amici, P Orsini, G Traquandi, L Corti, C Piutti, ...
Journal of medicinal chemistry 47 (13), 3367-3380, 2004
Benchmarking membrane protein detergent stability for improving throughput of high-resolution X-ray structures
Y Sonoda, S Newstead, NJ Hu, Y Alguel, E Nji, K Beis, S Yashiro, C Lee, ...
Structure 19 (1), 17-25, 2011
Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition
D Fancelli, D Berta, S Bindi, A Cameron, P Cappella, P Carpinelli, ...
Journal of medicinal chemistry 48 (8), 3080-3084, 2005
Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue
AD Cameron, M Ridderström, B Olin, MJ Kavarana, DJ Creighton, ...
Biochemistry 38 (41), 13480-13490, 1999
Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans
K Ito, S Ito, T Shimamura, S Weyand, Y Kawarasaki, T Misaka, K Abe, ...
Journal of molecular biology 408 (2), 177-186, 2011
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