Non-neuronal cells in amyotrophic lateral sclerosis—from pathogenesis to biomarkers BF Vahsen, E Gray, AG Thompson, O Ansorge, DC Anthony, SA Cowley, ... Nature Reviews Neurology 17 (6), 333-348, 2021 | 126 | 2021 |
Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation E Giacomelli, BF Vahsen, EL Calder, Y Xu, J Scaber, E Gray, R Dafinca, ... Cell Stem Cell 29 (1), 11-35, 2022 | 70 | 2022 |
Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing BF Vahsen, VT Ribas, J Sundermeyer, A Boecker, V Dambeck, C Lenz, ... Cell Death & Differentiation 27 (10), 2810-2827, 2020 | 48 | 2020 |
Human iPSC co-culture model to investigate the interaction between microglia and motor neurons BF Vahsen, E Gray, A Candalija, KML Cramb, J Scaber, R Dafinca, ... Scientific Reports 12 (1), 12606, 2022 | 23 | 2022 |
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9 BF Vahsen, S Nalluru, GR Morgan, L Farrimond, E Carroll, Y Xu, ... Nature Communications 14 (1), 5898, 2023 | 21 | 2023 |
AAV-mediated expression of dominant-negative ULK1 increases neuronal survival and enhances motor performance in the MPTP mouse model of Parkinson’s disease D Balke, L Tatenhorst, V Dambeck, VT Ribas, BF Vahsen, U Michel, ... Molecular Neurobiology 57 (2), 685-697, 2020 | 20 | 2020 |
AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo VT Ribas, BF Vahsen, L Tatenhorst, V Estrada, V Dambeck, RA Almeida, ... Cell Death & Disease 12 (2), 213, 2021 | 9 | 2021 |
ULK1 as a novel therapeutic target in neurodegeneration BF Vahsen, P Lingor Neural Regeneration Research 16 (6), 1212-1213, 2021 | 4 | 2021 |
Role of autophagic protein ULK1 in axonal degeneration and regeneration in rat cortical neurons in vitro BF Vahsen Georg-August-Universität Göttingen, 2021 | 2 | 2021 |
Dynactin-1 mediates rescue of impaired axonal transport due to reduced mitochondrial bioenergetics in amyotrophic lateral sclerosis motor neurons R Dafinca, C Tosat-Bitrian, E Carroll, BF Vahsen, J Gilbert-Jaramillo, ... Brain Communications 6 (5), fcae350, 2024 | 1 | 2024 |
Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons J Scaber, I Thomas-Wright, AJ Clark, Y Xu, BF Vahsen, M Carcolé, ... Stem Cell Reports, 2024 | | 2024 |
Recent insights from human induced pluripotent stem cell models into the role of microglia in amyotrophic lateral sclerosis LM Nikel, K Talbot, BF Vahsen BioEssays, 2400054, 2024 | | 2024 |
Neuro‐immune interactions in health and disease: Insights from FENS‐Hertie 2022 Winter School LB Binder, PB Rosa, BM de Sousa, LS Chagas, O Dubljević, ... European Journal of Neuroscience 59 (8), 1977-1992, 2024 | | 2024 |
Understanding the role of microglia in the pathogenesis of amyotrophic lateral sclerosis BF Vahsen University of Oxford, 2022 | | 2022 |