Maria Carla PARRINI
Maria Carla PARRINI
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Fibroblast heterogeneity and immunosuppressive environment in human breast cancer
A Costa, Y Kieffer, A Scholer-Dahirel, F Pelon, B Bourachot, M Cardon, ...
Cancer cell 33 (3), 463-479. e10, 2018
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch
M Lei, W Lu, W Meng, MC Parrini, MJ Eck, BJ Mayer, SC Harrison
Cell 102 (3), 387-397, 2000
Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells
M Reffay, MC Parrini, O Cochet-Escartin, B Ladoux, A Buguin, S Coscoy, ...
Nature cell biology 16 (3), 217-223, 2014
Oxidative stress promotes myofibroblast differentiation and tumour spreading
A Toullec, D Gerald, G Despouy, B Bourachot, M Cardon, S Lefort, ...
EMBO molecular medicine 2 (6), 211-230, 2010
Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1
MC Parrini, M Lei, SC Harrison, BJ Mayer
Molecular cell 9 (1), 73-83, 2002
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
F Pelon, B Bourachot, Y Kieffer, I Magagna, F Mermet-Meillon, I Bonnet, ...
Nature communications 11 (1), 404, 2020
Cdc42 is required for PIP2-induced actin polymerization and early development but not for cell viability
F Chen, L Ma, MC Parrini, X Mao, M Lopez, C Wu, PW Marks, L Davidson, ...
Current biology 10 (13), 758-765, 2000
RalB mobilizes the exocyst to drive cell migration
C Rossť, A Hatzoglou, MC Parrini, MA White, P Chavrier, J Camonis
Molecular and cellular biology, 2006
Cell type-specific regulation of RhoA activity during cytokinesis
H Yoshizaki, Y Ohba, MC Parrini, NG Dulyaninova, AR Bresnick, ...
Journal of Biological Chemistry 279 (43), 44756-44762, 2004
Dissecting effects of anti-cancer drugs and cancer-associated fibroblasts by on-chip reconstitution of immunocompetent tumor microenvironments
M Nguyen, A De Ninno, A Mencattini, F Mermet-Meillon, G Fornabaio, ...
Cell reports 25 (13), 3884-3893. e3, 2018
RASSF1A suppresses the invasion and metastatic potential of human non–small cell lung cancer cells by inhibiting YAP activation through the GEF-H1/RhoB pathway
F Dubois, M Keller, O Calvayrac, F Soncin, L Hoa, A Hergovich, ...
Cancer research 76 (6), 1627-1640, 2016
Gradients of Rac1 nanoclusters support spatial patterns of Rac1 signaling
A Remorino, S De Beco, F Cayrac, F Di Federico, G Cornilleau, ...
Cell reports 21 (7), 1922-1935, 2017
SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility
MC Parrini, A Sadou-Dubourgnoux, K Aoki, K Kunida, M Biondini, ...
Molecular cell 42 (5), 650-661, 2011
Automated velocity mapping of migrating cell populations (AVeMap)
M Deforet, MC Parrini, L Petitjean, M Biondini, A Buguin, J Camonis, ...
Nature methods 9 (11), 1081-1083, 2012
Dissecting activation of the PAK1 kinase at protrusions in living cells
MC Parrini, J Camonis, M Matsuda, J de Gunzburg
Journal of Biological Chemistry 284 (36), 24133-24143, 2009
Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments
A Mencattini, D Di Giuseppe, MC Comes, P Casti, F Corsi, FR Bertani, ...
Scientific reports 10 (1), 7653, 2020
Spatiotemporal regulation of the Pak1 kinase
MC Parrini, M Matsuda, J De Gunzburg
Biochemical Society Transactions 33 (4), 646-648, 2005
STK 38 kinase acts as XPO 1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes
APJ Martin, M Jacquemyn, J Lipecka, C Chhuon, VN Aushev, B Meunier, ...
EMBO reports 20 (11), e48150, 2019
RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1
M Biondini, G Duclos, N Meyer-Schaller, P Silberzan, J Camonis, ...
Scientific reports 5 (1), 11759, 2015
A family affair: A Ral-exocyst-centered network links Ras, Rac, Rho signaling to control cell migration
G Zago, M Biondini, J Camonis, MC Parrini
Small GTPases 10 (5), 323-330, 2019
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