| Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition BI Pereira, OP Devine, M Vukmanovic-Stejic, ES Chambers, ... Nature communications 10 (1), 2387, 2019 | 339 | 2019 |
| Human coronavirus OC43 associated with fatal encephalitis S Morfopoulou, JR Brown, EG Davies, G Anderson, A Virasami, W Qasim, ... New England Journal of Medicine 375 (5), 497-498, 2016 | 319 | 2016 |
| Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy L Al-Olabi, S Polubothu, K Dowsett, KA Andrews, P Stadnik, AP Joseph, ... The Journal of clinical investigation 128 (4), 1496-1508, 2018 | 254 | 2018 |
| Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants D Gibbons, P Fleming, A Virasami, ML Michel, NJ Sebire, K Costeloe, ... Nature medicine 20 (10), 1206-1210, 2014 | 222 | 2014 |
| Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes M Clarke, A Mackay, B Ismer, JC Pickles, RG Tatevossian, S Newman, ... Cancer discovery 10 (7), 942-963, 2020 | 206 | 2020 |
| Astrovirus VA1/HMO-C: an increasingly recognized neurotropic pathogen in immunocompromised patients JR Brown, S Morfopoulou, J Hubb, WA Emmett, W Ip, D Shah, T Brooks, ... Clinical Infectious Diseases 60 (6), 881-888, 2015 | 200 | 2015 |
| Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK … JR Apps, G Carreno, JM Gonzalez-Meljem, S Haston, R Guiho, ... Acta neuropathologica 135, 757-777, 2018 | 117 | 2018 |
| Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma JM Gonzalez-Meljem, S Haston, G Carreno, JR Apps, S Pozzi, C Stache, ... Nature communications 8 (1), 1819, 2017 | 100 | 2017 |
| Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors L Urbani, C Camilli, DE Phylactopoulos, C Crowley, D Natarajan, ... Nature communications 9 (1), 4286, 2018 | 88 | 2018 |
| MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma S Haston, S Pozzi, G Carreno, S Manshaei, L Panousopoulos, ... Development 144 (12), 2141-2152, 2017 | 88 | 2017 |
| Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours TJ Stone, A Keeley, A Virasami, W Harkness, M Tisdall, ... Acta neuropathologica 135, 115-129, 2018 | 70 | 2018 |
| Molecular analyses reveal inflammatory mediators in the solid component and cyst fluid of human adamantinomatous craniopharyngioma AM Donson, J Apps, AM Griesinger, V Amani, DA Witt, RCE Anderson, ... Journal of Neuropathology & Experimental Neurology 76 (9), 779-788, 2017 | 65 | 2017 |
| Proteomic analysis of the myocardium in hypertrophic obstructive cardiomyopathy CJ Coats, WE Heywood, A Virasami, N Ashrafi, P Syrris, C Dos Remedios, ... Circulation: Genomic and Precision Medicine 11 (12), e001974, 2018 | 61 | 2018 |
| Vps33b is crucial for structural and functional hepatocyte polarity J Hanley, DK Dhar, F Mazzacuva, R Fiadeiro, JJ Burden, AM Lyne, ... Journal of Hepatology 66 (5), 1001-1011, 2017 | 53 | 2017 |
| Imaging Invasion: Micro-CT imaging of adamantinomatous craniopharyngioma highlights cell type specific spatial relationships of tissue invasion JR Apps, JC Hutchinson, OJ Arthurs, A Virasami, A Joshi, ... Acta neuropathologica communications 4, 1-4, 2016 | 50 | 2016 |
| Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis S Morfopoulou, ET Mee, SM Connaughton, JR Brown, K Gilmour, ... Acta Neuropathologica 133, 139-147, 2017 | 45 | 2017 |
| Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation E Papaioannou, DC Yánez, S Ross, CI Lau, A Solanki, MM Chawda, ... The Journal of Clinical Investigation 129 (8), 3153-3170, 2019 | 44 | 2019 |
| Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer J Baruteau, DP Perocheau, J Hanley, M Lorvellec, E Rocha-Ferreira, ... Nature Communications 9 (1), 3505, 2018 | 43 | 2018 |
| Micro-CT and histological investigation of the spatial pattern of feto-placental vascular density R Aughwane, C Schaaf, JC Hutchinson, A Virasami, MA Zuluaga, ... Placenta 88, 36-43, 2019 | 42 | 2019 |
| Generation and clinical application of gene-modified autologous epidermal sheets in Netherton syndrome: lessons learned from a phase 1 trial WL Di, SM Lwin, A Petrova, C Bernadis, F Syed, F Farzaneh, D Moulding, ... Human gene therapy 30 (9), 1067-1078, 2019 | 35 | 2019 |
Thomas JacquesUCL Great Ormond Street Institute of Child HealthVerified email at ucl.ac.uk
