David H. Spencer
David H. Spencer
Assistant Professor, Division of Oncology, Department of Medicine, Washington University
Verified email at wustl.edu
TitleCited byYear
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
CK Stover, XQ Pham, AL Erwin, SD Mizoguchi, P Warrener, MJ Hickey, ...
Nature 406 (6799), 959, 2000
43532000
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Cancer Genome Atlas Research Network
New England Journal of Medicine 368 (22), 2059-2074, 2013
22802013
Comprehensive transposon mutant library of Pseudomonas aeruginosa
MA Jacobs, A Alwood, I Thaipisuttikul, D Spencer, E Haugen, S Ernst, ...
Proceedings of the National Academy of Sciences 100 (24), 14339-14344, 2003
9952003
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients
DA D'Argenio, M Wu, LR Hoffman, HD Kulasekara, E Déziel, EE Smith, ...
Molecular microbiology 64 (2), 512-533, 2007
2922007
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia
JM Klco, DH Spencer, CA Miller, M Griffith, TL Lamprecht, M O’Laughlin, ...
Cancer cell 25 (3), 379-392, 2014
2752014
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers
DA Russler-Germain, DH Spencer, MA Young, TL Lamprecht, CA Miller, ...
Cancer cell 25 (4), 442-454, 2014
2442014
Whole-genome sequence variation among multiple isolates of Pseudomonas aeruginosa
DH Spencer, A Kas, EE Smith, CK Raymond, EH Sims, M Hastings, ...
Journal of bacteriology 185 (4), 1316-1325, 2003
2302003
Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia
JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ...
Jama 314 (8), 811-822, 2015
2122015
Evidence for diversifying selection at the pyoverdine locus of Pseudomonas aeruginosa
EE Smith, EH Sims, DH Spencer, R Kaul, MV Olson
Journal of bacteriology 187 (6), 2138-2147, 2005
1602005
Genetic variation at the O-antigen biosynthetic locus in Pseudomonas aeruginosa
CK Raymond, EH Sims, A Kas, DH Spencer, TV Kutyavin, RG Ivey, ...
Journal of bacteriology 184 (13), 3614-3622, 2002
1602002
Validation of a next-generation sequencing assay for clinical molecular oncology
CE Cottrell, H Al-Kateb, AJ Bredemeyer, EJ Duncavage, DH Spencer, ...
The Journal of molecular diagnostics 16 (1), 89-105, 2014
1482014
Clinical next‐generation sequencing in patients with non–small cell lung cancer
IS Hagemann, S Devarakonda, CM Lockwood, DH Spencer, K Guebert, ...
Cancer 121 (4), 631-639, 2015
1382015
Comparison of clinical targeted next-generation sequence data from formalin-fixed and fresh-frozen tissue specimens
DH Spencer, JK Sehn, HJ Abel, MA Watson, JD Pfeifer, EJ Duncavage
The Journal of molecular diagnostics 15 (5), 623-633, 2013
1242013
Genomic impact of transient low-dose decitabine treatment on primary AML cells
JM Klco, DH Spencer, TL Lamprecht, SM Sarkaria, T Wylie, V Magrini, ...
Blood, The Journal of the American Society of Hematology 121 (9), 1633-1643, 2013
1192013
Genome mosaicism is conserved but not unique in Pseudomonas aeruginosa isolates from the airways of young children with cystic fibrosis
RK Ernst, DA D′ Argenio, JK Ichikawa, MG Bangera, S Selgrade, ...
Environmental microbiology 5 (12), 1341-1349, 2003
1122003
Detection of FLT3 internal tandem duplication in targeted, short-read-length, next-generation sequencing data
DH Spencer, HJ Abel, CM Lockwood, JE Payton, P Szankasi, TW Kelley, ...
The Journal of molecular diagnostics 15 (1), 81-93, 2013
972013
Performance of common analysis methods for detecting low-frequency single nucleotide variants in targeted next-generation sequence data
DH Spencer, M Tyagi, F Vallania, AJ Bredemeyer, JD Pfeifer, RD Mitra, ...
The Journal of Molecular Diagnostics 16 (1), 75-88, 2014
902014
CpG island hypermethylation mediated by DNMT3A is a consequence of AML progression
DH Spencer, DA Russler-Germain, S Ketkar, NM Helton, TL Lamprecht, ...
Cell 168 (5), 801-816. e13, 2017
732017
Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells
DH Spencer, MA Young, TL Lamprecht, NM Helton, R Fulton, ...
Leukemia 29 (6), 1279-1289, 2015
552015
IFRD1 is a candidate gene for SMNA on chromosome 7q22-q23
Z Brkanac, D Spencer, J Shendure, PD Robertson, M Matsushita, T Vu, ...
The American Journal of Human Genetics 84 (5), 692-697, 2009
522009
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Articles 1–20