Jeffrey Carroll
Jeffrey Carroll
Associate Professor, Behavioral Neuroscience, Department of Psychology, Western Washington
Verified email at wwu.edu - Homepage
TitleCited byYear
Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene/allele-specific silencing of mutant huntingtin
JB Carroll, SC Warby, AL Southwell, CN Doty, S Greenlee, N Skotte, ...
Molecular Therapy 19 (12), 2178-2185, 2011
1962011
CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup
SC Warby, A Montpetit, AR Hayden, JB Carroll, SL Butland, H Visscher, ...
The American Journal of Human Genetics 84 (3), 351-366, 2009
1922009
Automated deformation analysis in the YAC128 Huntington disease mouse model
JP Lerch, JB Carroll, S Spring, LN Bertram, C Schwab, MR Hayden, ...
Neuroimage 39 (1), 32-39, 2008
1482008
Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease
PR Joshi, NP Wu, VM André, DM Cummings, C Cepeda, JA Joyce, ...
Journal of Neuroscience 29 (8), 2414-2427, 2009
1332009
Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus
SC Warby, CN Doty, RK Graham, JB Carroll, YZ Yang, RR Singaraja, ...
Human molecular genetics 17 (15), 2390-2404, 2008
1222008
Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes
M Valenza, V Leoni, JM Karasinska, L Petricca, J Fan, J Carroll, ...
Journal of Neuroscience 30 (32), 10844-10850, 2010
1062010
Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo
RK Graham, Y Deng, J Carroll, K Vaid, C Cowan, MA Pouladi, M Metzler, ...
Journal of Neuroscience 30 (45), 15019-15029, 2010
1032010
Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease
JP Lerch, JB Carroll, A Dorr, S Spring, AC Evans, MR Hayden, JG Sled, ...
Neuroimage 41 (2), 243-251, 2008
972008
Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients
NH Skotte, AL Southwell, ME Østergaard, JB Carroll, SC Warby, CN Doty, ...
PloS one 9 (9), e107434, 2014
922014
Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain
JM Van Raamsdonk, M Metzler, E Slow, J Pearson, C Schwab, J Carroll, ...
Neurobiology of disease 26 (1), 189-200, 2007
922007
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation
M Valenza, JB Carroll, V Leoni, LN Bertram, I Björkhem, RR Singaraja, ...
Human molecular genetics 16 (18), 2187-2198, 2007
832007
Treating the whole body in Huntington's disease
JB Carroll, GP Bates, J Steffan, C Saft, SJ Tabrizi
The Lancet Neurology 14 (11), 1135-1142, 2015
812015
In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides
AL Southwell, NH Skotte, HB Kordasiewicz, ME Østergaard, AT Watt, ...
Molecular Therapy 22 (12), 2093-2106, 2014
802014
Parvoviral nuclear import: bypassing the host nuclear-transport machinery
S Cohen, AR Behzad, JB Carroll, N Pante
Journal of General Virology 87 (11), 3209-3213, 2006
662006
Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease
JB Carroll, JP Lerch, S Franciosi, A Spreeuw, N Bissada, RM Henkelman, ...
Neurobiology of disease 43 (1), 257-265, 2011
642011
A fully humanized transgenic mouse model of Huntington disease
AL Southwell, SC Warby, JB Carroll, CN Doty, NH Skotte, W Zhang, ...
Human molecular genetics 22 (1), 18-34, 2012
602012
Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14
K Huang, SS Sanders, R Kang, JB Carroll, L Sutton, J Wan, R Singaraja, ...
Human molecular genetics 20 (17), 3356-3365, 2011
582011
Cerebrospinal fluid levels of orexin‐A are not a clinically useful biomarker for Huntington disease
M Björkqvist, Å Petersén, J Nielsen, D Ecker, H Mulder, MR Hayden, ...
Clinical genetics 70 (1), 78-79, 2006
402006
Methods and compositions for the treatment of Huntington'S disease
M Hayden, J Carroll, S Warby
US Patent 8,679,750, 2014
352014
Selective reduction of allelic variants
CF Bennett, M Hayden, SM Freier, S Greenlee, J Carroll, S Warby, ...
US Patent 9,006,198, 2015
232015
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Articles 1–20