| Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability S Sharma, KM Doherty, RM Brosh Biochemical Journal 398 (3), 319-337, 2006 | 247 | 2006 |
| The FANCJ/MutLα interaction is required for correction of the cross‐link response in FA‐J cells M Peng, R Litman, J Xie, S Sharma, RM Brosh Jr, SB Cantor The EMBO journal 26 (13), 3238-3249, 2007 | 171 | 2007 |
| Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1 S Sharma, JA Sommers, S Choudhary, JK Faulkner, S Cui, L Andreoli, ... Journal of Biological Chemistry 280 (30), 28072-28084, 2005 | 161 | 2005 |
| WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork S Sharma, M Otterlei, JA Sommers, HC Driscoll, GL Dianov, HI Kao, ... Molecular biology of the cell 15 (2), 734-750, 2004 | 141 | 2004 |
| Analysis of the DNA Substrate Specificity of the Human BACH1 HelicaseAssociated with BreastCancer R Gupta, S Sharma, JA Sommers, Z Jin, SB Cantor, RM Brosh Jr Journal of Biological Chemistry 280 (27), 25450-25460, 2005 | 128 | 2005 |
| RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability S Sharma, DJ Stumpo, AS Balajee, CB Bock, PM Lansdorp, RM Brosh, ... Molecular and cellular biology 27 (5), 1784-1794, 2007 | 108 | 2007 |
| FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein R Gupta, S Sharma, JA Sommers, MK Kenny, SB Cantor, RM Brosh Blood 110 (7), 2390-2398, 2007 | 103 | 2007 |
| Stimulation of flap endonuclease-1 by the Bloom's syndrome protein S Sharma, JA Sommers, L Wu, VA Bohr, ID Hickson, RM Brosh Jr Journal of Biological Chemistry 279 (11), 9847-9856, 2004 | 103 | 2004 |
| Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges S Sharma, RM Brosh Jr PloS one 2 (12), e1297, 2007 | 99 | 2007 |
| RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination KM Doherty, S Sharma, LA Uzdilla, TM Wilson, S Cui, A Vindigni, ... Journal of Biological Chemistry 280 (30), 28085-28094, 2005 | 89 | 2005 |
| Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome AN Suhasini, NA Rawtani, Y Wu, JA Sommers, S Sharma, G Mosedale, ... The EMBO journal 30 (4), 692-705, 2011 | 86 | 2011 |
| A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster XL Li, T Hara, Y Choi, M Subramanian, P Francis, S Bilke, RL Walker, ... Molecular and cellular biology 34 (3), 533-550, 2014 | 80 | 2014 |
| DNA helicases as targets for anti-cancer drugs S Sharma, KM Doherty, RM Brosh Jr Current Medicinal Chemistry-Anti-Cancer Agents 5 (3), 183-199, 2005 | 77 | 2005 |
| A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis M Subramanian, P Francis, S Bilke, XL Li, T Hara, X Lu, MF Jones, ... Oncogene 34 (9), 1094-1104, 2015 | 65 | 2015 |
| Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer XL Li, M Subramanian, MF Jones, R Chaudhary, DK Singh, X Zong, ... Cell reports 20 (10), 2408-2423, 2017 | 63 | 2017 |
| p53 modulates RPA-dependent and RPA-independent WRN helicase activity JA Sommers, S Sharma, KM Doherty, P Karmakar, Q Yang, MK Kenny, ... Cancer research 65 (4), 1223-1233, 2005 | 60 | 2005 |
| The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein S Sharma, JA Sommers, HC Driscoll, L Uzdilla, TM Wilson, RM Brosh Jr Journal of Biological Chemistry 278 (26), 23487-23496, 2003 | 60 | 2003 |
| The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA S Sharma, JA Sommers, RK Gary, E Friedrich-Heineken, U Hübscher, ... Nucleic acids research 33 (21), 6769-6781, 2005 | 59 | 2005 |
| Human RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaks S Parvathaneni, A Stortchevoi, JA Sommers, RM Brosh Jr, S Sharma PLoS One 8 (5), e62481, 2013 | 50 | 2013 |
| In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication S Sharma, JA Sommers, RM Brosh Jr Human molecular genetics 13 (19), 2247-2261, 2004 | 48 | 2004 |
