|Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability|
S Sharma, KM Doherty, RM Brosh
Biochemical Journal 398 (3), 319-337, 2006
|The FANCJ/MutLα interaction is required for correction of the cross‐link response in FA‐J cells|
M Peng, R Litman, J Xie, S Sharma, RM Brosh Jr, SB Cantor
The EMBO journal 26 (13), 3238-3249, 2007
|Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1|
S Sharma, JA Sommers, S Choudhary, JK Faulkner, S Cui, L Andreoli, ...
Journal of Biological Chemistry 280 (30), 28072-28084, 2005
|WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork|
S Sharma, M Otterlei, JA Sommers, HC Driscoll, GL Dianov, HI Kao, ...
Molecular biology of the cell 15 (2), 734-750, 2004
|Analysis of the DNA Substrate Specificity of the Human BACH1 HelicaseAssociated with BreastCancer|
R Gupta, S Sharma, JA Sommers, Z Jin, SB Cantor, RM Brosh Jr
Journal of Biological Chemistry 280 (27), 25450-25460, 2005
|RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability|
S Sharma, DJ Stumpo, AS Balajee, CB Bock, PM Lansdorp, RM Brosh, ...
Molecular and cellular biology 27 (5), 1784-1794, 2007
|FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein|
R Gupta, S Sharma, JA Sommers, MK Kenny, SB Cantor, RM Brosh
Blood 110 (7), 2390-2398, 2007
|Stimulation of flap endonuclease-1 by the Bloom's syndrome protein|
S Sharma, JA Sommers, L Wu, VA Bohr, ID Hickson, RM Brosh Jr
Journal of Biological Chemistry 279 (11), 9847-9856, 2004
|Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges|
S Sharma, RM Brosh Jr
PloS one 2 (12), e1297, 2007
|RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination|
KM Doherty, S Sharma, LA Uzdilla, TM Wilson, S Cui, A Vindigni, ...
Journal of Biological Chemistry 280 (30), 28085-28094, 2005
|Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome|
AN Suhasini, NA Rawtani, Y Wu, JA Sommers, S Sharma, G Mosedale, ...
The EMBO journal 30 (4), 692-705, 2011
|A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster|
XL Li, T Hara, Y Choi, M Subramanian, P Francis, S Bilke, RL Walker, ...
Molecular and cellular biology 34 (3), 533-550, 2014
|DNA helicases as targets for anti-cancer drugs|
S Sharma, KM Doherty, RM Brosh Jr
Current Medicinal Chemistry-Anti-Cancer Agents 5 (3), 183-199, 2005
|A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis|
M Subramanian, P Francis, S Bilke, XL Li, T Hara, X Lu, MF Jones, ...
Oncogene 34 (9), 1094-1104, 2015
|Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer|
XL Li, M Subramanian, MF Jones, R Chaudhary, DK Singh, X Zong, ...
Cell reports 20 (10), 2408-2423, 2017
|p53 modulates RPA-dependent and RPA-independent WRN helicase activity|
JA Sommers, S Sharma, KM Doherty, P Karmakar, Q Yang, MK Kenny, ...
Cancer research 65 (4), 1223-1233, 2005
|The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein|
S Sharma, JA Sommers, HC Driscoll, L Uzdilla, TM Wilson, RM Brosh Jr
Journal of Biological Chemistry 278 (26), 23487-23496, 2003
|The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA|
S Sharma, JA Sommers, RK Gary, E Friedrich-Heineken, U Hübscher, ...
Nucleic acids research 33 (21), 6769-6781, 2005
|Human RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaks|
S Parvathaneni, A Stortchevoi, JA Sommers, RM Brosh Jr, S Sharma
PLoS One 8 (5), e62481, 2013
|In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication|
S Sharma, JA Sommers, RM Brosh Jr
Human molecular genetics 13 (19), 2247-2261, 2004