David Ochoa

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Pedro BeltraoAssociate Professor, ETH ZurichVerified email at ethz.ch
Ian DunhamEMBL-EBIVerified email at ebi.ac.uk
Mohd Anisul Karim, MD, MRCP, DPhilDirector, Medical Biology (Variant Bio)Verified email at variantbio.com
Jeremy SchwartzentruberIllumina Artificial Intelligence LabVerified email at illumina.com
Maya GhoussainiResearch Associate, Department of Oncology, University of CambridgeVerified email at medschl.cam.ac.uk
Cristina ViéitezInstitute of Funcional Biology and Genomics (IBFG) CSIC-University of SalamancaVerified email at usal.es
Andrew LeachHead of Chemical Biology, European Bioinformatics InstituteVerified email at ebi.ac.uk
André MateusAssistant Professor at Umeå University | Team Leader at Molecular Infection Medicine Sweden (MIMS)Verified email at umu.se
Mikhail SavitskiEMBLVerified email at embl.de
Florencio PazosComputational Systems Biology Group. Spanish National Biotechnology Center (CNB-CSIC)Verified email at cnb.csic.es
Alfonso ValenciaICREA Professor. Barcelona Supercomputing Center.Verified email at bsc.es
David JuanSpanish National Centre for BiotechnologyVerified email at cnb.csic.es
Pablo Porras MillánEMBL-EBIVerified email at ebi.ac.uk
Nassos TypasGroup Leader, EMBLVerified email at embl.de
Emanuel GonçalvesIST - Universidade de Lisboa & INESC-IDVerified email at tecnico.ulisboa.pt
Omar WagihDeep GenomicsVerified email at deepgenomics.com
Julio Saez RodriguezHeidelberg UniversityVerified email at uni-heidelberg.de
ENRIQUE CARRILLO DE SANTA PAU...IMDEA Food Institute (ROR 04g4ezh90). Madrid. SPAINVerified email at imdea.org
Juliane PernerComputational biologist, Novartis Institutes for BioMedical Research (NIBR)Verified email at novartis.com
Daniel RicoCABIMERVerified email at cabimer.es

David Ochoa

Platform Coordinator in OpenTargets (EMBL-EBI)

Verified email at ebi.ac.uk - Homepage

Computational Biology Drug Discovery Systems Biology Bioinformatics


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Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics M Ghoussaini, E Mountjoy, M Carmona, G Peat, EM Schmidt, A Hercules, ... Nucleic acids research 49 (D1), D1311-D1320, 2021	501	2021
An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci E Mountjoy, EM Schmidt, M Carmona, J Schwartzentruber, G Peat, ... Nature genetics 53 (11), 1527-1533, 2021	435	2021
The functional landscape of the human phosphoproteome D Ochoa, AF Jarnuczak, C Viéitez, M Gehre, M Soucheray, A Mateus, ... Nature biotechnology 38 (3), 365-373, 2020	410	2020
Open Targets Platform: supporting systematic drug–target identification and prioritisation D Ochoa, A Hercules, M Carmona, D Suveges, A Gonzalez-Uriarte, ... Nucleic acids research 49 (D1), D1302-D1310, 2021	381	2021
The next-generation Open Targets Platform: reimagined, redesigned, rebuilt D Ochoa, A Hercules, M Carmona, D Suveges, J Baker, C Malangone, ... Nucleic acids research 51 (D1), D1353-D1359, 2023	265	2023
The protactable genome M Schneider, CJ Radoux, A Hercules, D Ochoa, I Dunham, LP Zalmas, ... Nature reviews Drug discovery 20 (10), 789-797, 2021	185	2021
Human genetics evidence supports two-thirds of the 2021 FDA-approved drugs D Ochoa, M Karim, M Ghoussaini, DG Hulcoop, EM McDonagh, I Dunham Nat Rev Drug Discov 21 (8), 551, 2022	157	2022
An atlas of human kinase regulation D Ochoa, M Jonikas, RT Lawrence, B El Debs, J Selkrig, A Typas, J Villén, ... Molecular systems biology 12 (12), 888, 2016	121	2016
Benchmarking substrate-based kinase activity inference using phosphoproteomic data C Hernandez-Armenta, D Ochoa, E Gonçalves, J Saez-Rodriguez, ... Bioinformatics 33 (12), 1845-1851, 2017	88	2017
Studying the co-evolution of protein families with the Mirrortree web server D Ochoa, F Pazos Bioinformatics 26 (10), 1370-1371, 2010	88	2010
Mondo: unifying diseases for the world, by the world NA Vasilevsky, NA Matentzoglu, S Toro, JE Flack IV, H Hegde, DR Unni, ... MedRxiv, 2022.04. 13.22273750, 2022	86	2022
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set N Del-Toro, M Duesbury, M Koch, L Perfetto, A Shrivastava, D Ochoa, ... Nature communications 10 (1), 10, 2019	66	2019
Epigenomic co-localization and co-evolution reveal a key role for 5hmC as a communication hub in the chromatin network of ESCs D Juan, J Perner, EC de Santa Pau, S Marsili, D Ochoa, HR Chung, ... Cell reports 14 (5), 1246-1257, 2016	61	2016
Network expansion of genetic associations defines a pleiotropy map of human cell biology I Barrio-Hernandez, J Schwartzentruber, A Shrivastava, N Del-Toro, ... Nature genetics 55 (3), 389-398, 2023	60	2023
Conserved phosphorylation hotspots in eukaryotic protein domain families MJ Strumillo, M Oplová, C Viéitez, D Ochoa, M Shahraz, BP Busby, ... Nature communications 10 (1), 1977, 2019	54	2019
Democratizing knowledge representation with BioCypher S Lobentanzer, P Aloy, J Baumbach, B Bohar, VJ Carey, P Charoentong, ... Nature Biotechnology 41 (8), 1056-1059, 2023	49	2023
High-throughput functional characterization of protein phosphorylation sites in yeast C Viéitez, BP Busby, D Ochoa, A Mateus, D Memon, M Galardini, U Yildiz, ... Nature Biotechnology 40 (3), 382-390, 2022	48*	2022
Systematic analysis of transcriptional and post-transcriptional regulation of metabolism in yeast E Gonçalves, Z Raguz Nakic, M Zampieri, O Wagih, D Ochoa, U Sauer, ... PLoS computational biology 13 (1), e1005297, 2017	46	2017
Practical aspects of protein co-evolution D Ochoa, F Pazos Frontiers in cell and developmental biology 2, 14, 2014	40	2014
Detection of significant protein coevolution D Ochoa, D Juan, A Valencia, F Pazos Bioinformatics 31 (13), 2166-2173, 2015	34	2015

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