Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75 P Casaccia-Bonnefil, BD Carter, RT Dobrowsky, MV Chao Nature 383 (6602), 716-719, 1996 | 997 | 1996 |
Ceramide activates heterotrimeric protein phosphatase 2A RT Dobrowsky, C Kamibayashi, MC Mumby, YA Hannun Journal of Biological Chemistry 268 (21), 15523-15530, 1993 | 818 | 1993 |
Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor RT Dobrowsky, MH Werner, AM Castellino, MV Chao, YA Hannun Science 265 (5178), 1596-1599, 1994 | 759 | 1994 |
A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids JA Chavez, TA Knotts, LP Wang, G Li, RT Dobrowsky, GL Florant, ... Journal of Biological Chemistry 278 (12), 10297-10303, 2003 | 726 | 2003 |
Ceramide stimulates a cytosolic protein phosphatase. RT Dobrowsky, YA Hannun Journal of Biological Chemistry 267 (8), 5048-5051, 1992 | 494 | 1992 |
Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction. RA Wolff, RT Dobrowsky, A Bielawska, LM Obeid, YA Hannun Journal of Biological Chemistry 269 (30), 19605-19609, 1994 | 347 | 1994 |
Neurotrophins Induce Sphingomyelin Hydrolysis: MODULATION BY CO-EXPRESSION OF p75NTR WITH Trk RECEPTORS (∗) RT Dobrowsky, GM Jenkins, YA Hannun Journal of Biological Chemistry 270 (38), 22135-22142, 1995 | 324 | 1995 |
Association of p75NTR with caveolin and localization of neurotrophin-induced sphingomyelin hydrolysis to caveolae TR Bilderback, RJ Grigsby, RT Dobrowsky Journal of Biological Chemistry 272 (16), 10922-10927, 1997 | 205 | 1997 |
Caveolin interacts with Trk A and p75NTR and regulates neurotrophin signaling pathways TR Bilderback, VR Gazula, MP Lisanti, RT Dobrowsky Journal of Biological Chemistry 274 (1), 257-263, 1999 | 201 | 1999 |
Ceramide-mediated growth inhibition and CAPP are conserved in Saccharomyces cerevisiae JD Fishbein, RT Dobrowsky, A Bielawska, S Garrett, YA Hannun Journal of Biological Chemistry 268 (13), 9255-9261, 1993 | 187 | 1993 |
Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats E Akude, E Zherebitskaya, SKR Chowdhury, DR Smith, RT Dobrowsky, ... Diabetes 60 (1), 288-297, 2011 | 179 | 2011 |
Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab) GJ Biessels, V Bril, NA Calcutt, NE Cameron, MA Cotter, R Dobrowsky, ... Journal of the peripheral nervous system 19 (2), 77-87, 2014 | 174 | 2014 |
The Dlk1-Gtl2 locus preserves LT-HSC function by inhibiting the PI3K-mTOR pathway to restrict mitochondrial metabolism P Qian, XC He, A Paulson, Z Li, F Tao, JM Perry, F Guo, M Zhao, L Zhi, ... Cell stem cell 18 (2), 214-228, 2016 | 170 | 2016 |
Ceramide displaces cholesterol from lipid rafts and decreases the association of the cholesterol binding protein caveolin-1 C Yu, M Alterman, RT Dobrowsky Journal of lipid research 46 (8), 1678-1691, 2005 | 149 | 2005 |
Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach? KL Farmer, C Li, RT Dobrowsky Pharmacological reviews 64 (4), 880-900, 2012 | 144 | 2012 |
Sphingolipid signalling domains floating on rafts or buried in caves? RT Dobrowsky Cellular Signalling 12 (2), 81-90, 2000 | 141 | 2000 |
Ceramide-activated protein phosphatase: partial purification and relationship to protein phosphatase 2A RT Dobrowsky, YA Hannun Advances in lipid research 25, 91-104, 1993 | 133 | 1993 |
Neurotrophic modulation of myelinated cutaneous innervation and mechanical sensory loss in diabetic mice JA Christianson, JM Ryals, MS Johnson, RT Dobrowsky, DE Wright Neuroscience 145 (1), 303-313, 2007 | 128 | 2007 |
Stabilization of the cyclin‐dependent kinase 5 activator, p35, by paclitaxel decreases β‐amyloid toxicity in cortical neurons G Li, A Faibushevich, BJ Turunen, SO Yoon, G Georg, ML Michaelis, ... Journal of neurochemistry 84 (2), 347-362, 2003 | 108 | 2003 |
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice MJ Urban, C Li, C Yu, Y Lu, JM Krise, MP McIntosh, RA Rajewski, ... ASN neuro 2 (4), AN20100015, 2010 | 106 | 2010 |