An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates JH Erasmus, AP Khandhar, MA O’Connor, AC Walls, EA Hemann, ... Science translational medicine 12 (555), eabc9396, 2020 | 207 | 2020 |
A chikungunya fever vaccine utilizing an insect-specific virus platform JH Erasmus, AJ Auguste, JT Kaelber, H Luo, SL Rossi, K Fenton, G Leal, ... Nature medicine 23 (2), 192-199, 2017 | 138 | 2017 |
A nanostructured lipid carrier for delivery of a replicating viral RNA provides single, low-dose protection against Zika JH Erasmus, AP Khandhar, J Guderian, B Granger, J Archer, M Archer, ... Molecular Therapy 26 (10), 2507-2522, 2018 | 131 | 2018 |
Chikungunya virus strains show lineage-specific variations in virulence and cross-protective ability in murine and nonhuman primate models RM Langsjoen, SL Haller, CJ Roy, H Vinet-Oliphant, NA Bergren, ... MBio 9 (2), 10.1128/mbio. 02449-17, 2018 | 88 | 2018 |
Eilat virus induces both homologous and heterologous interference F Nasar, JH Erasmus, AD Haddow, RB Tesh, SC Weaver Virology 484, 51-58, 2015 | 86 | 2015 |
Status of research and development of vaccines for chikungunya C Smalley, JH Erasmus, CB Chesson, DWC Beasley Vaccine 34 (26), 2976-2981, 2016 | 85 | 2016 |
Intramuscular delivery of replicon RNA encoding ZIKV-117 human monoclonal antibody protects against Zika virus infection JH Erasmus, J Archer, J Fuerte-Stone, AP Khandhar, E Voigt, B Granger, ... Molecular Therapy-Methods & Clinical Development 18, 402-414, 2020 | 83 | 2020 |
Chikungunya virus as cause of febrile illness outbreak, Chiapas, Mexico, 2014 TF Kautz, EE Díaz-González, JH Erasmus, IR Malo-García, RM Langsjoen, ... Emerging infectious diseases 21 (11), 2070, 2015 | 74 | 2015 |
Development of vaccines for chikungunya fever JH Erasmus, SL Rossi, SC Weaver The Journal of infectious diseases 214 (suppl_5), S488-S496, 2016 | 72 | 2016 |
Utilization of an Eilat virus-based chimera for serological detection of chikungunya infection JH Erasmus, J Needham, S Raychaudhuri, MS Diamond, DWC Beasley, ... PLoS neglected tropical diseases 9 (10), e0004119, 2015 | 64 | 2015 |
Heterologous Immunization With Defined RNA and Subunit Vaccines Enhances T Cell Responses That Protect Against Leishmania donovani MS Duthie, N Van Hoeven, Z MacMillen, A Picone, R Mohamath, ... Frontiers in immunology 9, 2420, 2018 | 55 | 2018 |
Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics P Gilchuk, RG Bombardi, JH Erasmus, Q Tan, R Nargi, C Soto, P Abbink, ... Nature biomedical engineering 4 (11), 1030-1043, 2020 | 54 | 2020 |
Novel insect-specific eilat virus-based chimeric vaccine candidates provide durable, mono-and multivalent, single-dose protection against lethal alphavirus challenge JH Erasmus, RL Seymour, JT Kaelber, DY Kim, G Leal, MB Sherman, ... Journal of virology 92 (4), 10.1128/jvi. 01274-17, 2018 | 53 | 2018 |
A newly isolated reovirus has the simplest genomic and structural organization of any reovirus AJ Auguste, JT Kaelber, EB Fokam, H Guzman, CVF Carrington, ... Journal of virology 89 (1), 676-687, 2015 | 53 | 2015 |
Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates JH Erasmus, AP Khandhar, AC Walls, EA Hemann, MA O’Connor, ... bioRxiv, 2020.05. 28.121640, 2020 | 37 | 2020 |
Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine DW Hawman, K Meade-White, C Clancy, J Archer, T Hinkley, ... EBioMedicine 83, 2022 | 35 | 2022 |
Replicating RNA vaccination elicits an unexpected immune response that efficiently protects mice against lethal Crimean-Congo hemorrhagic fever virus challenge SS Leventhal, K Meade-White, D Rao, E Haddock, J Leung, D Scott, ... EBioMedicine 82, 2022 | 26 | 2022 |
SARS-CoV2 variant-specific replicating RNA vaccines protect from disease following challenge with heterologous variants of concern DW Hawman, K Meade-White, J Archer, SS Leventhal, D Wilson, C Shaia, ... Elife 11, e75537, 2022 | 22 | 2022 |
Molecular virologic and clinical characteristics of a chikungunya fever outbreak in La Romana, Dominican Republic, 2014 RM Langsjoen, RJ Rubinstein, TF Kautz, AJ Auguste, JH Erasmus, ... PLoS neglected tropical diseases 10 (12), e0005189, 2016 | 22 | 2016 |
Isolation of a novel insect-specific flavivirus with immunomodulatory effects in vertebrate systems AJ Auguste, RM Langsjoen, DL Porier, JH Erasmus, NA Bergren, ... Virology 562, 50-62, 2021 | 17 | 2021 |