| PARP-3 and APLF function together to accelerate nonhomologous end-joining SL Rulten, AEO Fisher, I Robert, MC Zuma, M Rouleau, L Ju, G Poirier, ... Molecular cell 41 (1), 33-45, 2011 | 359 | 2011 |
| XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia NC Hoch, H Hanzlikova, SL Rulten, M Tétreault, E Komulainen, L Ju, ... Nature 541 (7635), 87-91, 2017 | 244 | 2017 |
| PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage SL Rulten, A Rotheray, RL Green, GJ Grundy, DAQ Moore, ... Nucleic acids research 42 (1), 307-314, 2014 | 196 | 2014 |
| APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks N Iles, S Rulten, SF El-Khamisy, KW Caldecott Molecular and cellular biology, 2007 | 190 | 2007 |
| APLF promotes the assembly and activity of non‐homologous end joining protein complexes GJ Grundy, SL Rulten, Z Zeng, R Arribas‐Bosacoma, N Iles, K Manley, ... The EMBO journal 32 (1), 112-125, 2013 | 174 | 2013 |
| TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function F Gómez-Herreros, JHM Schuurs-Hoeijmakers, M McCormack, ... Nature genetics 46 (5), 516-521, 2014 | 153 | 2014 |
| Molecular cloning and expression of human cGMP-binding cGMP-specific phosphodiesterase (PDE5) P Stacey, S Rulten, A Dapling, SC Phillips Biochemical and biophysical research communications 247 (2), 249-254, 1998 | 120 | 1998 |
| The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function C Breslin, P Hornyak, A Ridley, SL Rulten, H Hanzlikova, AW Oliver, ... Nucleic acids research 43 (14), 6934-6944, 2015 | 111 | 2015 |
| APLF (C2orf13) is a novel component of poly (ADP-ribose) signaling in mammalian cells SL Rulten, F Cortes-Ledesma, L Guo, NJ Iles, KW Caldecott Molecular and cellular biology, 2008 | 107 | 2008 |
| DNA strand break repair and neurodegeneration SL Rulten, KW Caldecott DNA repair 12 (8), 558-567, 2013 | 91 | 2013 |
| One ring to bring them all—the role of Ku in mammalian non-homologous end joining GJ Grundy, HA Moulding, KW Caldecott, SL Rulten DNA repair 17, 30-38, 2014 | 87 | 2014 |
| The PARP inhibitor AZD2461 provides insights into the role of PARP3 inhibition for both synthetic lethality and tolerability with chemotherapy in preclinical models. SL Rulten, AN Cranston, R Odedra, H Brown, JE Jaspers, L Jones, ... Cancer Research 76 (20), 6084-6094, 2016 | 83 | 2016 |
| PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2BGlu2 GJ Grundy, LM Polo, Z Zeng, SL Rulten, NC Hoch, P Paomephan, Y Xu, ... Nature communications 7 (1), 12404, 2016 | 76 | 2016 |
| The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins GJ Grundy, SL Rulten, R Arribas-Bosacoma, K Davidson, Z Kozik, ... Nature communications 7 (1), 11242, 2016 | 73 | 2016 |
| The human FK506-binding proteins: characterization of human FKBP19 SL Rulten, RA Kinloch, H Tateossian, C Robinson, L Gettins, JE Kay Mammalian genome 17, 322-331, 2006 | 73 | 2006 |
| Identification of eukaryotic parvulin homologues: a new subfamily of peptidylprolyl cis–trans isomerases S Rulten, J Thorpe, J Kay Biochemical and biophysical research communications 259 (3), 557-562, 1999 | 53 | 1999 |
| Non‐homologous end joining: common interaction sites and exchange of multiple factors in the DNA repair process SL Rulten, GJ Grundy Bioessays 39 (3), 1600209, 2017 | 51 | 2017 |
| Shortfalls in the peptidyl-prolyl cis–trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias JR Thorpe, S Mosaheb, L Hashemzadeh-Bonehi, NJ Cairns, JE Kay, ... Neurobiology of disease 17 (2), 237-249, 2004 | 49 | 2004 |
| Utilizing the Peptidyl-Prolyl Cis-Trans Isomerase Pin1 as a Probe of Its Phosphorylated Target Proteins: Examples of Binding to Nuclear Proteins in a Human … JR Thorpe, SJ Morley, SL Rulten Journal of Histochemistry & Cytochemistry 49 (1), 97-107, 2001 | 43 | 2001 |
| Sp1 and NFκB pathways are regulated in brain in response to acute and chronic ethanol SL Rulten, TL Ripley, CL Hunt, DN Stephens, LV Mayne Genes, Brain and Behavior 5 (3), 257-273, 2006 | 42 | 2006 |
