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James Hewitson
James Hewitson
Unknown affiliation
Verified email at york.ac.uk
Title
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Cited by
Year
Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity
JP Hewitson, JR Grainger, RM Maizels
Molecular and biochemical parasitology 167 (1), 1-11, 2009
8652009
Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway
JR Grainger, KA Smith, JP Hewitson, HJ McSorley, Y Harcus, KJ Filbey, ...
Journal of Experimental Medicine 207 (11), 2331-2341, 2010
5602010
IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1
SJ Jenkins, D Ruckerl, GD Thomas, JP Hewitson, S Duncan, ...
Journal of Experimental Medicine 210 (11), 2477-2491, 2013
4482013
Immunomodulation by helminth parasites: defining mechanisms and mediators
HJ McSorley, JP Hewitson, RM Maizels
International journal for parasitology 43 (3-4), 301-310, 2013
3652013
The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory–secretory products
JP Hewitson, YM Harcus, RS Curwen, AA Dowle, AK Atmadja, PD Ashton, ...
Molecular and biochemical parasitology 160 (1), 8-21, 2008
2802008
Susceptibility and immunity to helminth parasites
RM Maizels, JP Hewitson, KA Smith
Current opinion in immunology 24 (4), 459-466, 2012
2672012
Commensal-pathogen interactions in the intestinal tract: lactobacilli promote infection with, and are promoted by, helminth parasites
LA Reynolds, KA Smith, KJ Filbey, Y Harcus, JP Hewitson, SA Redpath, ...
Gut microbes 5 (4), 522-532, 2014
2562014
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells
CJC Johnston, DJ Smyth, RB Kodali, MPJ White, Y Harcus, KJ Filbey, ...
Nature communications 8 (1), 1741, 2017
1782017
Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) proteins
JP Hewitson, Y Harcus, J Murray, M van Agtmaal, KJ Filbey, JR Grainger, ...
Journal of proteomics 74 (9), 1573-1594, 2011
1782011
Immunity induced by the radiation‐attenuated schistosome vaccine
JP Hewitson, PA Hamblin, AP Mountford
Parasite immunology 27 (7‐8), 271-280, 2005
1752005
Modulation of the host's immune response by schistosome larvae
SJ Jenkins, JP Hewitson, GR Jenkins, AP Mountford
Parasite immunology 27 (10‐11), 385-393, 2005
1712005
HpARI protein secreted by a helminth parasite suppresses interleukin-33
M Osbourn, DC Soares, F Vacca, ES Cohen, IC Scott, WF Gregory, ...
Immunity 47 (4), 739-751. e5, 2017
1652017
Vaccination against helminth parasite infections
JP Hewitson, RM Maizels
Expert review of vaccines 13 (4), 473-487, 2014
1562014
Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection
KJ Filbey, JR Grainger, KA Smith, L Boon, N Van Rooijen, Y Harcus, ...
Immunology and cell biology 92 (5), 436-448, 2014
1492014
Immune modulation and modulators in Heligmosomoides polygyrus infection
RM Maizels, JP Hewitson, J Murray, YM Harcus, B Dayer, KJ Filbey, ...
Experimental parasitology 132 (1), 76-89, 2012
1452012
Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and-independent pathways
SJ Jenkins, JP Hewitson, S Ferret-Bernard, AP Mountford
International immunology 17 (11), 1409-1418, 2005
992005
Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens …
JP Hewitson, KJ Filbey, J Esser-von Bieren, M Camberis, C Schwartz, ...
PLoS pathogens 11 (3), e1004676, 2015
802015
Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths
KA Smith, KJ Filbey, LA Reynolds, JP Hewitson, Y Harcus, L Boon, ...
Mucosal immunology 9 (2), 428-443, 2016
742016
The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an ‘M2’phenotype in response to Th2 …
KJ Mylonas, SJ Jenkins, RFP Castellan, D Ruckerl, K McGregor, ...
Immunobiology 220 (7), 924-933, 2015
662015
Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity
JP Hewitson, AC Ivens, Y Harcus, KJ Filbey, HJ McSorley, J Murray, ...
PLoS pathogens 9 (8), e1003492, 2013
662013
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