| RING domain E3 ubiquitin ligases RJ Deshaies, CAP Joazeiro Annual review of biochemistry 78, 399-434, 2009 | 3112 | 2009 |
| Function and regulation of cullin–RING ubiquitin ligases MD Petroski, RJ Deshaies Nature reviews Molecular cell biology 6 (1), 9-20, 2005 | 2487 | 2005 |
| Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation KM Sakamoto, KB Kim, A Kumagai, F Mercurio, CM Crews, RJ Deshaies Proceedings of the National Academy of Sciences 98 (15), 8554-8559, 2001 | 1807 | 2001 |
| A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides RJ Deshaies, BD Koch, M Werner-Washburne, EA Craig, R Schekman Nature 332 (6167), 800-805, 1988 | 1793 | 1988 |
| How proteolysis drives the cell cycle RW King, RJ Deshaies, JM Peters, MW Kirschner Science 274 (5293), 1652-1659, 1996 | 1738 | 1996 |
| SCF and Cullin/Ring H2-based ubiquitin ligases RJ Deshaies Annual review of cell and developmental biology 15 (1), 435-467, 1999 | 1689 | 1999 |
| Role of Rpn11 Metalloprotease in Deubiquitination and Degradation by the 26S Proteasome R Verma, L Aravind, R Oania, WH McDonald, JR Yates III, EV Koonin, ... Science 298 (5593), 611-615, 2002 | 1333 | 2002 |
| A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p RMR Feldman, CC Correll, KB Kaplan, RJ Deshaies Cell 91 (2), 221-230, 1997 | 1066 | 1997 |
| Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex W Shou, JH Seol, A Shevchenko, C Baskerville, D Moazed, ZWS Chen, ... Cell 97 (2), 233-244, 1999 | 899 | 1999 |
| Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1 GA Cope, GSB Suh, L Aravind, SE Schwarz, SL Zipursky, EV Koonin, ... Science 298 (5593), 608-611, 2002 | 838 | 2002 |
| Promotion of NEDD8-CUL1 conjugate cleavage by COP9 signalosome S Lyapina, G Cope, A Shevchenko, G Serino, T Tsuge, C Zhou, DA Wolf, ... Science 292 (5520), 1382-1385, 2001 | 823 | 2001 |
| Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes R Verma, S Chen, R Feldman, D Schieltz, J Yates, J Dohmen, ... Molecular biology of the cell 11 (10), 3425-3439, 2000 | 674 | 2000 |
| Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase R Verma, RS Annan, MJ Huddleston, SA Carr, G Reynard, RJ Deshaies Science 278 (5337), 455-460, 1997 | 636 | 1997 |
| Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4 Z Skrott, M Mistrik, KK Andersen, S Friis, D Majera, J Gursky, T Ozdian, ... Nature 552 (7684), 194-199, 2017 | 591 | 2017 |
| Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIR1 in mediating auxin response C Schwechheimer, G Serino, J Callis, WL Crosby, S Lyapina, ... Science 292 (5520), 1379-1382, 2001 | 573 | 2001 |
| Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system R Verma, R Oania, J Graumann, RJ Deshaies Cell 118 (1), 99-110, 2004 | 550 | 2004 |
| Cdc53/cullin and the essential Hrt1 RING–H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34 JH Seol, RMR Feldman, W Zachariae, A Shevchenko, CC Correll, ... Genes & development 13 (12), 1614-1626, 1999 | 538 | 1999 |
| A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. RJ Deshaies, R Schekman The Journal of cell biology 105 (2), 633-645, 1987 | 532 | 1987 |
| Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells SK Radhakrishnan, CS Lee, P Young, A Beskow, JY Chan, RJ Deshaies Molecular cell 38 (1), 17-28, 2010 | 526 | 2010 |
| Chemical genetic control of protein levels: selective in vivo targeted degradation JS Schneekloth Jr, FN Fonseca, M Koldobskiy, A Mandal, R Deshaies, ... Journal of the American Chemical Society 126 (12), 3748-3754, 2004 | 507 | 2004 |
