Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts W Sha, J Moore, K Chen, AD Lassaletta, CS Yi, JJ Tyson, JC Sible Proc Natl Acad Sci 100 (3), 975, 2003 | 565 | 2003 |
Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1 J Yang, ESG Bardes, JD Moore, J Brennan, MA Powers, S Kornbluth Genes & development 12 (14), 2131-2143, 1998 | 444 | 1998 |
Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1 JD Moore, J Yang, R Truant, S Kornbluth The Journal of cell biology 144 (2), 213-224, 1999 | 287 | 1999 |
Kinesin proteins: A phylum of motors for microtubule‐based motility JD Moore, SA Endow Bioessays 18 (3), 207-219, 1996 | 218 | 1996 |
Unmasking the S-phase-promoting potential of cyclin B1 JD Moore, JA Kirk, T Hunt Science 300 (5621), 987-990, 2003 | 162 | 2003 |
The Ran‐GTPase and cell‐cycle control JD Moore Bioessays 23 (1), 77-85, 2001 | 139 | 2001 |
Pin1 inhibitors: Pitfalls, progress and cellular pharmacology JD Moore, A Potter Bioorganic & medicinal chemistry letters 23 (15), 4283-4291, 2013 | 119 | 2013 |
Review Article: The pre-chorismate (shikimate) and quinate pathways in filamentous fungi: theoretical and practical aspects AR Hawkins, HK Lamb, JD Moore, IG Charles, CF Roberts Journal of general microbiology 139 (12), 2891-2899, 1993 | 106 | 1993 |
Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution A Potter, V Oldfield, C Nunns, C Fromont, S Ray, CJ Northfield, CJ Bryant, ... Bioorganic & medicinal chemistry letters 20 (22), 6483-6488, 2010 | 100 | 2010 |
Triazolo [1, 5-a] pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR CM Richardson, DS Williamson, MJ Parratt, J Borgognoni, AD Cansfield, ... Bioorganic & medicinal chemistry letters 16 (5), 1353-1357, 2006 | 97 | 2006 |
Synthetic lethal targeting of ARID1A-mutant ovarian clear cell tumors with dasatinib RE Miller, R Brough, I Bajrami, CT Williamson, S McDade, J Campbell, ... Molecular cancer therapeutics, 2016 | 95 | 2016 |
Structure-guided design of pyrazolo [1, 5-a] pyrimidines as inhibitors of human cyclin-dependent kinase 2 DS Williamson, MJ Parratt, JF Bower, JD Moore, CM Richardson, ... Bioorganic & medicinal chemistry letters 15 (4), 863-867, 2005 | 95 | 2005 |
Structure-guided design of α-amino acid-derived Pin1 inhibitors AJ Potter, S Ray, L Gueritz, CL Nunns, CJ Bryant, SF Scrace, ... Bioorganic & medicinal chemistry letters 20 (2), 586-590, 2010 | 94 | 2010 |
Structure-guided design of α-amino acid-derived Pin1 inhibitors AJ Potter, S Ray, L Gueritz, CL Nunns, CJ Bryant, SF Scrace, ... Bioorganic & medicinal chemistry letters 20 (2), 586-590, 2010 | 94 | 2010 |
The impact of CRISPR–Cas9 on target identification and validation JD Moore Drug discovery today 20 (4), 450-457, 2015 | 70 | 2015 |
Fragment screening by weak affinity chromatography: comparison with established techniques for screening against HSP90 E Meiby, H Simmonite, L le Strat, B Davis, N Matassova, JD Moore, ... Analytical chemistry 85 (14), 6756-6766, 2013 | 70 | 2013 |
Identification of the Nuclear Localization Signal inXenopus Cyclin E and Analysis of Its Role in Replication and Mitosis JD Moore, S Kornbluth, T Hunt Molecular biology of the cell 13 (12), 4388-4400, 2002 | 62 | 2002 |
Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping CM Richardson, CL Nunns, DS Williamson, MJ Parratt, P Dokurno, ... Bioorganic & medicinal chemistry letters 17 (14), 3880-3885, 2007 | 57 | 2007 |
Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance C Sage, S Lawo, P Panicker, TME Scales, SA Rahman, AS Little, ... Scientific reports 7 (1), 17693, 2017 | 52 | 2017 |
VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells JD Moore, A Staniszewska, T Shaw, J D'Alessandro, B Davis, A Surgenor, ... Oncotarget 5 (24), 12862, 2014 | 50 | 2014 |